Bandet MV, Winship IR. Aberrant cortical activity, functional connectivity, and neural assembly architecture after photothrombotic stroke in mice eLife Neuroscience. eLife12:RP90080
Gupta SJ, Churchward MA, Todd KG, Winship IR. Pleiotrophin Signals Through ALK Receptor to Enhance the Growth of Neurons in the Presence of Inhibitory Chondroitin Sulfate Proteoglycans. Neurosci Insights. 2023 Jul 15;18:26331055231186993. doi: 10.1177/26331055231186993.
Bui TA, Jickling GC, Winship IR. Neutrophil dynamics and inflammaging in acute ischemic stroke: A transcriptomic review. Front. Aging Neurosci. 2022 Dec 22;14. doi: 10.3389/fnagi.2022.1041333
Abbasi-Habashi S, Jickling GC, Winship IR. Immune Modulation as a Key Mechanism for the Protective Effects of Remote Ischemic Conditioning After Stroke. Front Neurol. 2021 Dec 9;12:746486. doi: 10.3389/fneur.2021.746486.PMID: 34956045; PMCID: PMC8695500.
Nomani AZ, Kamtchum Tatuene J, Rempel JL, Jeerakathil T, Winship IR, Khan KA, Buck BH, Shuaib A, Jickling GC. Association of CT-Based Hypoperfusion Index With Ischemic Core Enlargement in Patients With Medium and Large Vessel Stroke. Neurology. 2021 Nov 23;97(21):e2079-e2087. doi: 10.1212/WNL.0000000000012855. Epub 2021 Oct 4. PMID: 34607925; PMCID: PMC8610618.
Bandet MV, Dong B, Winship IR. Distinct patterns of activity in individual cortical neurons and local networks in primary somatosensory cortex of mice evoked by square-wave mechanical limb stimulation. PLoS One. 2021 Apr 29;16(4):e0236684. doi: 10.1371/journal.pone.0236684. PMID: 33914738; PMCID: PMC8084136.
Jesudasan SJB, Gupta SJ, Churchward MA, Todd KG, Winship IR. Inflammatory Cytokine Profile and Plasticity of Brain and Spinal Microglia in Response to ATP and Glutamate. Front Cell Neurosci. 2021 Apr 6;15:634020. doi:10.3389/fncel.2021.634020. PMID: 33889075; PMCID: PMC8057348.
Georgeson P, Pope BJ, Rosty C, Clendenning M, Mahmood K, Joo JE, Walker R, Hutchinson RA, Preston S, Como J, Joseland S, Win AK, Macrae FA, Hopper JL, Mouradov D, Gibbs P, Sieber OM, O'Sullivan DE, Brenner DR, Gallinger S, Jenkins MA, Winship IM, Buchanan DD. Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers. Gut. 2021 Nov;70(11):2138-2149. doi: 10.1136/gutjnl-2019-320462. Epub 2021 Jan 7. PMID: 33414168; PMCID: PMC8260632.
Kalisvaart ACJ, Wilkinson CM, Gu S, Kung TFC, Yager J, Winship IR, van Landeghem FKH, Colbourne F. An update to the Monro-Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke. Sci Rep. 2020 Dec 16;10(1):22013. doi: 10.1038/s41598-020-78880-4. PMID: 33328490; PMCID: PMC7745016.
Faughnan ME, Mager JJ, Hetts SW, Palda VA, Lang-Robertson K, Buscarini E, Deslandres E, Kasthuri RS, Lausman A, Poetker D, Ratjen F, Chesnutt MS, Clancy M, Whitehead KJ, Al-Samkari H, Chakinala M, Conrad M, Cortes D, Crocione C, Darling J, de Gussem E, Derksen C, Dupuis-Girod S, Foy P, Geisthoff U, Gossage JR, Hammill A, Heimdal K, Henderson K, Iyer VN, Kjeldsen AD, Komiyama M, Korenblatt K, McDonald J, McMahon J, McWilliams J, Meek ME, Mei-Zahav M, Olitsky S, Palmer S, Pantalone R, Piccirillo JF, Plahn B, Porteous MEM, Post MC, Radovanovic I, Rochon PJ, Rodriguez-Lopez J, Sabba C, Serra M, Shovlin C, Sprecher D, White AJ, Winship I, Zarrabeitia R. Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia. Ann Intern Med. 2020 Dec 15;173(12):989-1001. doi: 10.7326/M20-1443. Epub 2020 Sep
Ma J, Ma Y, Shuaib A, Winship IR. Improved collateral flow and reduced damage after remote ischemic perconditioning during distal middle cerebral artery occlusion in aged rats. Sci Rep. 2020 Jul 24;10(1):12392. doi: 10.1038/s41598-020-69122-8. PMID: 32709950; PMCID: PMC7381676.
Anderson MD, Paylor JW, Scott GA, Greba Q, Winship IR, Howland JG. ChABC infusions into medial prefrontal cortex, but not posterior parietal cortex, improve the performance of rats tested on a novel, challenging delay in the touchscreen TUNL task. Learn Mem. 2020 May 15;27(6):222-235. doi: 10.1101/lm.050245.119. PMID: 32414940; PMCID: PMC7233150.
Parray A, Ma Y, Alam M, Akhtar N, Salam A, Mir F, Qadri S, Pananchikkal SV, Priyanka R, Kamran S, Winship IR, Shuaib A. An increase in AMPK/e-NOS signaling and attenuation of MMP-9 may contribute to remote ischemic perconditioning associated neuroprotection in rat model of focal ischemia. Brain Res. 2020 Aug 1;1740:146860. doi: 10.1016/j.brainres.2020.146860. Epub 2020 Apr 27. PMID:32353433.
Ma J, Ma Y, Shuaib A, Winship IR. Impaired Collateral Flow in Pial Arterioles of Aged Rats During Ischemic Stroke. Transl Stroke Res. 2020 Apr;11(2):243-253. doi: 10.1007/s12975-019-00710-1. Epub 2019 Jun 15. PMID: 31203565; PMCID: PMC7067739.
Howland JG, Greenshaw AJ, Winship IR. Practical Aspects of Animal Models of Psychiatric Disorders. Can J Psychiatry. 2019 Jan;64(1):3-4. doi:10.1177/0706743718771833. PMID: 30789052; PMCID: PMC6364137.
Catuneanu A, Paylor JW, Winship I, Colbourne F, Kerr BJ. Sex differences in central nervous system plasticity and pain in experimental autoimmune encephalomyelitis. Pain. 2019 May;160(5):1037-1049. doi: 10.1097/j.pain.0000000000001483. PMID: 30649100.
Winship IR, Dursun SM, Baker GB, Balista PA, Kandratavicius L, Maia-de- Oliveira JP, Hallak J, Howland JG. An Overview of Animal Models Related to Schizophrenia. Can J Psychiatry. 2019 Jan;64(1):5-17. doi: 10.1177/0706743718773728. Epub 2018 May 9. PMID: 29742910; PMCID: PMC6364139.
Paylor JW, Wendlandt E, Freeman TS, Greba Q, Marks WN, Howland JG, Winship IR. Impaired Cognitive Function after Perineuronal Net Degradation in the Medial Prefrontal Cortex. eNeuro. 2018 Dec 28;5(6):ENEURO.0253-18.2018. doi: 10.1523/ENEURO.0253-18.2018. PMID: 30627657; PMCID: PMC6325561.
MacKay MB, Paylor JW, Wong JTF, Winship IR, Baker GB, Dursun SM. Multidimensional Connectomics and Treatment-Resistant Schizophrenia: Linking Phenotypic Circuits to Targeted Therapeutics. Front Psychiatry. 2018 Oct 30;9:537. doi: 10.3389/fpsyt.2018.00537. PMID: 30425662; PMCID: PMC6218602.
Wiersma AM, Winship IR. In vivo Use of Dextran-based Anterograde Cortical Tracers to Assess the Integrity of the Cortical Spinal Tract. Bio Protoc. 2018 May 20;8(10):e2862. doi: 10.21769/BioProtoc.2862. PMID: 34285978; PMCID: PMC8275257.
Wiersma AM, Winship IR. Induction of Photothrombotic Stroke in the Sensorimotor Cortex of Rats andPreparation of Tissue for Analysis of Stroke Volume andTopographical Cortical Localization of Ischemic Infarct. Bio Protoc. 2018 May 20;8(10):e2861. doi: 10.21769/BioProtoc.2861. PMID: 34285977; PMCID: PMC8275251.
Wiersma AM, Fouad K, Winship IR. Enhancing Spinal Plasticity Amplifies the Benefits of Rehabilitative Training and Improves Recovery from Stroke. J Neurosci. 2017 Nov 8;37(45):10983-10997. doi: 10.1523/JNEUROSCI.0770-17.2017. Epub 2017 Oct 12. PMID: 29025926; PMCID: PMC6596489.
Radziwon-Balicka A, Lesyk G, Back V, Fong T, Loredo-Calderon EL, Dong B, El-Sikhry H, El-Sherbeni AA, El-Kadi A, Ogg S, Siraki A, Seubert JM, Santos-Martinez MJ, Radomski MW, Velazquez-Martinez CA, Winship IR, Jurasz P. Differential eNOS-signalling by platelet subpopulations regulates adhesion and aggregation. Cardiovasc Res. 2017 Dec 1;113(14):1719-1731. doi:10.1093/cvr/cvx179. PMID: 29016749; PMCID: PMC5852541.
Li Y, Lucas-Osma AM, Black S, Bandet MV, Stephens MJ, Vavrek R, Sanelli L, Fenrich KK, Di Narzo AF, Dracheva S, Winship IR, Fouad K, Bennett DJ. Pericytes impair capillary blood flow and motor function after chronic spinal cord injury. Nat Med. 2017 Jun;23(6):733-741. doi: 10.1038/nm.4331. Epub 2017 May 1. PMID: 28459438; PMCID: PMC5716958.
Ma J, Ma Y, Dong B, Bandet MV, Shuaib A, Winship IR. Prevention of the collapse of pial collaterals by remote ischemic perconditioning during acute ischemic stroke. J Cereb Blood Flow Metab. 2017 Aug;37(8):3001-3014. doi: 10.1177/0271678X16680636. Epub 2016 Jan 1. PMID: 27909265; PMCID: PMC5536804.
Paylor JW, Lins BR, Greba Q, Moen N, de Moraes RS, Howland JG, Winship IR. Developmental disruption of perineuronal nets in the medial prefrontal cortex after maternal immune activation. Sci Rep. 2016 Nov 23;6:37580. doi: 10.1038/srep37580. PMID: 27876866; PMCID: PMC5120325.
Alles SRA, Bandet MV, Eppler K, Noh MC, Winship IR, Baker G, Ballanyi K, Smith PA. Acute anti-allodynic action of gabapentin in dorsal horn and primary somatosensory cortex: Correlation of behavioural and physiological data. Neuropharmacology. 2017 Feb;113(Pt A):576-590. doi: 10.1016/j.neuropharm.2016.11.011. Epub 2016 Nov 14. PMID: 27856391.
Potter LE, Paylor JW, Suh JS, Tenorio G, Caliaperumal J, Colbourne F, Baker G, Winship I, Kerr BJ. Altered excitatory-inhibitory balance within somatosensory cortex is associated with enhanced plasticity and pain sensitivity in a mouse model of multiple sclerosis. J Neuroinflammation. 2016 Jun 10;13(1):142. doi: 10.1186/s12974-016-0609-4. PMID: 27282914; PMCID: PMC4901403.
Weilinger NL, Lohman AW, Rakai BD, Ma EM, Bialecki J, Maslieieva V, Rilea T, Bandet MV, Ikuta NT, Scott L, Colicos MA, Teskey GC, Winship IR, Thompson RJ. Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity. Nat Neurosci. 2016 Mar;19(3):432-42. doi: 10.1038/nn.4236. Epub 2016 Feb 8. PMID: 26854804.
Ramakrishnan G, Dong B, Todd KG, Shuaib A, Winship IR. Erratum to: Transient Aortic Occlusion Augments Collateral Blood Flow and Reduces Mortality During Severe Ischemia Due to Proximal Middle Cerebral Artery Occlusion. Transl Stroke Res. 2016 Jun;7(3):239-240. doi: 10.1007/s12975-016-0452-z. Erratum for: Transl Stroke Res. 2016 Apr;7(2):149-55. doi: 10.1007/s12975-015-0443-5. Epub 2015 Dec 26. PMID: 26818735; PMCID: PMC4969957.
Ramakrishnan G, Dong B, Todd KG, Shuaib A, Winship IR. Transient Aortic Occlusion Augments Collateral Blood Flow and Reduces Mortality During Severe Ischemia due to Proximal Middle Cerebral Artery Occlusion. Transl Stroke Res. 2016 Apr;7(2):149-55. doi: 10.1007/s12975-015-0443-5. Epub 2015 Dec 26. Erratum in: Transl Stroke Res. 2016 Jun;7(3):239-40. PMID: 26706246; PMCID: PMC4770060.
Thorburn KC, Paylor JW, Webber CA, Winship IR, Kerr BJ. Facial hypersensitivity and trigeminal pathology in mice with experimental autoimmun encephalomyelitis. Pain. 2016 Mar;157(3):627-642. doi: 10.1097/j.pain.0000000000000409. PMID: 26545087
Daude N, Gapeshina H, Dong B, Winship I, Westaway D. Neuroprotective properties of the PrP-like Shadoo glycoprotein assessed in the middle cerebral artery occlusion model of ischemia. Prion. 2015;9(5):376-93. doi: 10.1080/19336896.2015.1105432. PMID: 26516793; PMCID: PMC4964864.
Benson C, Paylor JW, Tenorio G, Winship I, Baker G, Kerr BJ. Voluntary wheel running delays disease onset and reduces pain hypersensitivity in early experimental autoimmune encephalomyelitis (EAE). Exp Neurol. 2015 Sep;271:279-90. doi: 10.1016/j.expneurol.2015.05.017. Epub 2015 May 29. PMID: 26033473.
Winship IR. Cerebral collaterals and collateral therapeutics for acute ischemic stroke. Microcirculation. 2015 Apr;22(3):228-36. doi: 10.1111/micc.12177. PMID: 25351102.
Baskar Jesudasan SJ, Todd KG, Winship IR. Reduced inflammatory phenotype in microglia derived from neonatal rat spinal cord versus brain. PLoS One. 2014 Jun 10;9(6):e99443. doi: 10.1371/journal.pone.0099443. PMID: 24914808; PMCID: PMC4051776.
Winship IR. Laser speckle contrast imaging to measure changes in cerebral blood flow. Methods Mol Biol. 2014;1135:223-35. doi: 10.1007/978-1-4939-0320-7_19. PMID: 24510868.
Sist B, Fouad K, Winship IR. Plasticity beyond peri-infarct cortex: spinal up regulation of structural plasticity, neurotrophins, and inflammatory cytokines during recovery from cortical stroke. Exp Neurol. 2014 Feb;252:47-56. doi: 10.1016/j.expneurol.2013.11.019. Epub 2013 Nov 26. PMID: 24291254.
Li Y, Li L, Stephens MJ, Zenner D, Murray KC, Winship IR, Vavrek R, Baker GB, Fouad K, Bennett DJ. Synthesis, transport, and metabolism of serotonin formed from exogenously applied 5-HTP after spinal cord injury in rats. J Neurophysiol. 2014 Jan;111(1):145-63. doi: 10.1152/jn.00508.2013. Epub 2013 Sep 25. PMID: 24068759; PMCID: PMC3921369.
Winship IR, Armitage GA, Ramakrishnan G, Dong B, Todd KG, Shuaib A. Augmenting collateral blood flow during ischemic stroke via transient aortic occlusion. J Cereb Blood Flow Metab. 2014 Jan;34(1):61-71. doi: 10.1038/jcbfm.2013.162. Epub 2013 Sep 18. PMID: 24045399; PMCID: PMC3887343.
Lai AY, Dibal CD, Armitage GA, Winship IR, Todd KG. Distinct activation profiles in microglia of different ages: a systematic study in isolated embryonic to aged microglial cultures. Neuroscience. 2013 Dec 19;254:185-95. doi: 10.1016/j.neuroscience.2013.09.010. Epub 2013 Sep 13. PMID: 24042036.
Winship IR. Improved cerebral blood flow measurement with multiexposure speckle imaging. J Cereb Blood Flow Metab. 2013 Jun;33(6):797. doi: 10.1038/jcbfm.2013.59. Epub 2013 Apr 10. PMID: 23571284; PMCID: PMC3677121.
Armitage GA, Todd KG, Shuaib A, Winship IR. Laser speckle contrast imaging of collateral blood flow during acute ischemic stroke. J Cereb Blood Flow Metab. 2010 Aug;30(8):1432-6. doi: 10.1038/jcbfm.2010.73. Epub 2010 Jun 2. PMID: 20517321; PMCID: PMC2949243.
Winship IR, Murphy TH. Remapping the somatosensory cortex after stroke: insight from imaging the synapse to network. Neuroscientist. 2009 Oct;15(5):507-24. doi: 10.1177/1073858409333076. Epub 2009 Jul 21. PMID: 19622841.
Brown CE, Aminoltejari K, Erb H, Winship IR, Murphy TH. In vivo voltage-sensitive dye imaging in adult mice reveals that somatosensory maps lost to stroke are replaced over weeks by new structural and functional circuits with prolonged modes of activation within both the peri-infarct zone and distant sites. J Neurosci. 2009 Feb 11;29(6):1719-34. doi: 10.1523/JNEUROSCI.4249-08.2009. PMID: 19211879; PMCID: PMC6666293.
45: Winship IR, Murphy TH. In vivo calcium imaging reveals functional rewiring of single somatosensory neurons after stroke. J Neurosci. 2008 Jun 25;28(26):6592-606. doi: 10.1523/JNEUROSCI.0622-08.2008. PMID: 18579732; PMCID: PMC6670410.
Winship IR, Plaa N, Murphy TH. Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo. J Neurosci. 2007 Jun 6;27(23):6268-72. doi: 10.1523/JNEUROSCI.4801-06.2007. PMID: 17554000; PMCID: PMC6672142.
Winship IR, Pakan JM, Todd KG, Wong-Wylie DR. A comparison of ventral tegmental neurons projecting to optic flow regions of the inferior olive vs. the hippocampal formation. Neuroscience. 2006 Aug 11;141(1):463-73. doi: 10.1016/j.neuroscience.2006.03.057. Epub 2006 May 15. PMID: 16698184.
Winship IR, Wylie DR. Receptive-field structure of optic flow responsive Purkinje cells in the vestibulocerebellum of pigeons. Vis Neurosci. 2006 Jan-Feb;23(1):115-26. doi: 10.1017/S0952523806231109. PMID: 16597355.
Winship IR, Crowder NA, Wylie DR. Quantitative reassessment of speed tuning in the accessory optic system and pretectum of pigeons. J Neurophysiol. 2006 Jan;95(1):546-51. doi: 10.1152/jn.00921.2005. Epub 2005 Sep 28. PMID: 16192326.
Wylie DR, Ogilvie CJ, Crowder NA, Barkley RR, Winship IR. Telencephalic projections to the nucleus of the basal optic root and pretectal nucleus lentiformis mesencephali in pigeons. Vis Neurosci. 2005 Mar-Apr;22(2):237-47. doi: 10.1017/S0952523805221090. PMID: 15935115.
Pakan JM, Todd KG, Nguyen AP, Winship IR, Hurd PL, Jantzie LL, Wylie DR. Inferior olivary neurons innervate multiple zones of the flocculus in pigeons (Columba livia). J Comp Neurol. 2005 May 30;486(2):159-68. doi: 10.1002/cne.20523. PMID: 15844212.
Winship IR, Hurd PL, Wylie DR. Spatiotemporal tuning of optic flow inputs to the vestibulocerebellum in pigeons: differences between mossy and climbing fiber pathways. J Neurophysiol. 2005 Mar;93(3):1266-77. doi: 10.1152/jn.00815.2004. Epub 2004 Oct 13. PMID: 15483061.
Nguyen AP, Spetch ML, Crowder NA, Winship IR, Hurd PL, Wylie DR. A dissociation of motion and spatial-pattern vision in the avian telencephalon: implications for the evolution of "visual streams". J Neurosci. 2004 May 26;24(21):4962-70. doi: 10.1523/JNEUROSCI.0146-04.2004. PMID: 15163688; PMCID: PMC6729365.
Wylie DR, Brown MR, Winship IR, Crowder NA, Todd KG. Zonal organization of the vestibulocerebellum in pigeons (Columba livia): III. Projections of the translation zones of the ventral uvula and nodulus. J Comp Neurol. 2003 Oct 13;465(2):179-94. doi: 10.1002/cne.10857. PMID: 12949780.
Wylie DR, Brown MR, Barkley RR, Winship IR, Crowder NA, Todd KG. Zonal organization of the vestibulocerebellum in pigeons (Columba livia): II. Projections of the rotation zones of the flocculus. J Comp Neurol. 2003 Feb 3;456(2):140-53. doi: 10.1002/cne.10508. PMID: 12509871.
Winship IR, Wylie DR. Zonal organization of the vestibulocerebellum in pigeons (Columba livia): I. Climbing fiber input to the flocculus. J Comp Neurol. 2003 Feb 3;456(2):127-39. doi: 10.1002/cne.10507. PMID: 12509870.
Winship IR, Wylie DR. Responses of neurons in the medial column of the inferior olive in pigeons to translational and rotational optic flowfields. Exp Brain Res. 2001 Nov;141(1):63-78. doi: 10.1007/s002210100845. PMID: 11685411.
Crowder NA, Winship IR, Wylie DR. Topographic organization of inferior olive cells projecting to translational zones in the vestibulocerebellum of pigeons. J Comp Neurol. 2000 Mar 27;419(1):87-95. PMID: 10717641.
Wylie DR, Winship IR, Glover RG. Projections from the medial column of the inferior olive to different classes of rotation-sensitive Purkinje cells in the flocculus of pigeons. Neurosci Lett. 1999 Jun 18;268(2):97-100. doi: 10.1016/s0304-3940(99)00390-0. PMID: 10400087.