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2009

165.	Wang, H.; Lu, M.; Tang, M.-S.; Van Houten, B.; Ross, J.B.A; Weinfeld, M.; Le, X.C. DNA Wrapping is required for DNA damage recognition in the E. coli DNA nucleotide excision repair pathway. Proceedings of the National Academy of Sciences USA, 106, 12849-12854 (2009).
164.	Qin, J.; Lehr, C.R.; Yuan, C.; Le, X.C.; McDermott, T.R.; Rosen, B.P. Biotransformation of arsenic by a Yellowstone thermoacidophilic eukaryotic alga. Proceedings of the National Academy of Sciences USA, 106, 5213-5217 (2009).
163.	Yan, H.; Wang, N.; Weinfeld, M.; Cullen, W.R.; Le, X.C. Identification of arsenic-binding proteins in human cells by affinity chromatography and mass spectrometry. Analytical Chemistry, 81, 4144-4152 (2009).
162.	Zhao, Q.; Lu, X.; Yuan, C.; Li, X.-F.; Le, X.C. Aptamer-linked assay for thrombin using gold nanoparticle amplification and inductively coupled plasma mass spectrometry detection. Analytical Chemistry, 81, 7484-7489 (2009).
161.	Zhang, H.; Li, X.-F.; Le, X.C. Differentiation and detection of PDGF isomers and their receptors by tunable aptamer capillary electrophoresis. Analytical Chemistry, 81, 7795-7800 (2009).
160.	Wang, Z.; Lu, M.; Wang, X.; Yin, R.; Song, Y.; Le, X.C. Wang, H. Quantum dots enhanced ultrasensitive detection of DNA adducts. Analytical Chemistry, 81, 10285-10289 (2009)
159.	Shen, S.; Lee, J; Cullen, W.R.; Le, X.C Arsenite and its mono- and di-methylated trivalent metabolites enhance the formation of BPDE-DNA adducts in Xeroderma pigmentosum complementation group A cells. Chemical Research in Toxicology, 22, 382-390 (2009).
158.	Drobna, Z.; Narenmandura, H.; Kubachka, K.M.; Edwards, B.C.; Herbin-Davis, K.; Styblo, M.; Le, X.C.; Creed, J.T.; Maeda, N.; Hughes, M.F.; Thomas, D.J. Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate. Chemical Research in Toxicology, 22, 1713-1720 (2009). Cover feature.
157.	Wang, C.; Feng, F.; Wang, Z.; Li, T.; Le, X.C.; Wang, H. Synthesis and characterization of long DNA probes containing a single stereomer of anti-BPDE-N2-dG. Chemical Research in Toxicology, 22, 676-682 (2009).
156.	Naranmandura, H.; Ogra, Y.; Iwata, K.; Lee, J.; Suzuki, K.T.; Weinfeld, M.; Le, X.C. Evidence for toxicity differences between inorganic arsenite and thioarsenicals in human bladder cancer. Toxicology and Applied Pharmacology, 238, 133-140 (2009).
155.	Naranmandura, H.; Suzuki, N.; Takano, J.; McKnight-Whitford, T.; Ogra, Y.; Suzuki, K.T.; Le, X.C. Systemic distribution and speciation of diphenylarsinic acid fed to rats. Toxicology and Applied Pharmacology, 237, 214-220 (2009).
154.	Charoensuk, V.; Gati, W.; Weinfeld, M.; Le, X.C. Differential cytotoxic effects of arsenic compounds in human acute promyelocytic leukemia cells. Toxicology and Applied Pharmacology, 239, 64-70 (2009).
153.	Suzuki, S.; Arnold, L.L.; Pennington, K.L.; Chen, B.; Le, X.C.; Cohen, S.M. Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium. Toxicology Letters, 187, 124-129 (2009).
152.	Lu, M.; Wang, H.; Li, X.F.; Lu, X.; Le, X.C. Enzymatic digestion and chromatographic analysis of arsenic species released from proteins. Journal of Chromatography A, 1216, 3985-3991 (2009).
151.	Goulko, A.A.; Feng Li, F.; Le, X.C. Bioanalytical applications of aptamer and molecular beacon probes in fluorescence affinity assays. Trends in Analytical Chemistry, 28, 878-892 (2009).
150.	LeBlanc, A.; Shen, S.; Lew, K.; Weinfeld, M.; Le, X.C. Detection of BPDE-DNA adducts in mononuclear white blood cells by capillary electrophoresis immunoassay and its application to studying the effect of glutathione depletion. Electrophoresis, 30, 1558-1563 (2009).
149.	Li, R.B.; Wu, R.A.; Wu, M.H.; Zou, H.F.; Ma, H.; Yang, L.; Le, X.C. MEKC-LIF analysis of rhodamine123 delivered by carbon nanotubes in K562 cells. Electrophoresis, 30, 1906-1912 (2009).
148.	Zhao, Q.; Le, X.C. Recent advances in aptamer affinity chromatography. Chinese Journal of Chromatography, 27(5), 556-565 (2009).
147.	Liu, J.; Le, X.C. Interaction of arsenic species with proteins. Journal of Analytical Science, 25(4), 465-472 (2009).
146.	Chen, B.; Narenmandula, H.; Lu, M.; Le, X.C. Metabolism, toxicity, and biomonitoring of arsenic species. Progress in Chemistry, 21, 474-482 (2009).
145.	Yuan, C.; Le, X.C. Arsenic speciation analysis. Progress in Chemistry, 467-473 (2009).
144.	Wade, T.J.; Xia, Y.; Wu, K.; Li, Y.; Ning, Z.; Le, X.C.; Lu, X.; Feng, Y.; He, X.; Mumford, J.L. Increased mortality associated with well-water arsenic exposure in Inner Mongolia, China. International Journal of Environmental Research and Public Health, 6(3), 1107-1123 (2009).
143.	Xia, Y.; Wade, T.J.; Wu, K.; Li, Y.; Ning, Z.; Le, X.C.; He, X.; Chen, B.; Feng, Y.; Mumford, J.L. Well water arsenic exposure, arsenic induced skin-lesions and self-reported morbidity in Inner Mongolia. International Journal of Environmental Research and Public Health, 6, 1010-1025 (2009).
142.	Lu, X.; Nguyen, N.; Gabos, S.; Le, X.C. Arsenic speciation in cattail (Typha latifolia) using chromatography and mass spectrometry. Molecular Nutrition and Food Research, 53, 566-571 (2009).
141.	Guthrie, J.W.; Shao, Y.; Le, X.C. Aptamers in affinity separations: Capillary electrophoresis. In Y-F. Li and Y. Lu (Ed). Functional Nucleic Acids for Sensing and Other Analytical Applications. Chapter 7, 255-270 (2009).
2008
140.	Zhang, H.; Li, X.-F.; Le, X.C. Tunable aptamer capillary electrophoresis and its application to protein analysis. Journal of American Chemical Society, 130, 34-35 (2008).
139.	Hamula, C.L.A.; Zhang, H.; Guan, L.L.; Li, X.-F.; Le, X.C. Selection of aptamers against live bacterial cells. Analytical Chemistry, 80, 7812-7819 (2008).
138.	Zhao, Q.; Li, X.-F.; Shao, Y.; Le, X.C. Aptamer-based affinity chromatographic assays for thrombin. Analytical Chemistry, 80, 7586-7593 (2008).
137.	Zhao, Q.; Li, X.-F.; Le, X.C. Aptamer-modified monolithic capillary chromatography for protein separation and detection. Analytical Chemistry, 80, 3915-3920 (2008).
136.	Shen, L.; Chen, Z.; Li, Y.; He, S.; Xie, S.; Xu, X.; Liang, Z.; Meng, X.; Li, Q.; Zhu, Z.; Li, M.; Le, X.C.; Shao, Y. Electrochemical DNAzyme sensor for lead based on amplification of DNA-Au bio-bar codes. Analytical Chemistry, 80, 6323-6328 (2008).
135.	Lu, M.; Wang, H.; Li, X.-F.; Le, X.C. Identification of reactive cysteines in a protein using arsenic labeling and collision-induced dissociation tandem mass spectrometry. Journal of Proteome Research, 7, 3080-3090 (2008).
134.	Yuan, C.; Lu, X.; Qin, J.; Rosen, B.P.; Le, X.C. Volatile Arsenic Species Released from Escherichia coli Expressing the AsIII S-adenosylmethionine Methyltransferase Gene. Environmental Science and Technology, 42, 3201-3206 (2008).
133.	Yuan, C.; Lu, X.; Orr, N.; Wang, Z.; Xia, Y.; Wade, T.; Mumford, J.; Le, X.C. Arsenic speciation analysis in human saliva. Clinical Chemistry, 54, 163-171 (2008).
132.	Shen, S.; Lee, J.; Weinfeld, M.; Le, X.C. Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis. Molecular Carcinogenesis, 47, 508-518 (2008).
131.	Lew, K.; Yuan, C.; Acker, J.A.; Le, X.C. Salivary arsenic as a biomarker for arsenic exposure. Cell Biology and Toxicology, 24, 367-371 (2008).
130.	Nascimento, M.G.; Suzuki, S.; Wei, M.; Tiwari, A.; Arnold, L.L.; Lu, X.; Le, X.C.; Cohen, S.M. Cytotoxicity of combinations of arsenicals on rat urinary bladder urothelial cells in vitro. Toxicology, 249, 69-74 (2008).
129.	Goulko, A.A.; Zhao, Q.; Guthrie, J.W.; Zou, H., Le, X.C. Fluorescence Polarization: Recent Bioanalytical Applications, Pitfalls, and Future Trends. In U. Resch-Genger (Ed). Methods and Applications of Fluorescence. Springer Series Fluorescence, 5, 303-322 (2008).
2007
128.	Zhang, H.; Zhao, Q.; Li, X.-F.; Le, X.C. Ultrasensitive assays for proteins Analyst, 132, 724-737 (2007).
127.	Lu, M.; Wang, H.; Li, X.-F.; Arnold, L.L; Cohen, S.M.; Le, X.C. Binding of dimethylarsinous acid to cysteine 13 in the alpha chain of rat hemoglobin is responsible for retention of arsenic in rat blood. Chemical Research in Toxicology, 20, 27-37 (2007).
126.	Wang, Z.; Zhang, H.; Li, X.F.; Le, X.C. Study of interactions between arsenicals and thioredoxins (human and E. coli) using mass spectrometry. Rapid Communication in Mass Spectrometry, 21, 3658-3666 (2007).
125.	Cohen, S.M.; Ohnishi, T.; Arnold, L.L.; Le, X.C. Arsenic-induced bladder cancer in an animal model. Toxicology and Applied Pharmacology, 222, 258-263 (2007).
124.	Li, X.S.; Glasauer, S.; Le, X.C. Speciation of vanadium in oilsand coke and bacterial culture by high performance liquid chromatography inductively coupled plasma mass spectrometry. Analytica Chimica Acta, 602, 17-22 (2007).
123.	Muangnoi, P.; Lee, J.; Thepouyporn, A.; Lu, M.; Le, X.C.; Weinfeld, M.; Changbumrung, S. Cytotoxicity, apoptosis and DNA damage induced by Alpinia galanga rhizome extract. Planta Medica, 73, 748-54 (2007).
122.	Zhao, Q.; Le, X.C. Environmental analysis of single cells. Analytical and Bioanalytical Chemistry, 387, 45-49 (2007).
121.	Xiao, H.; Yang, L.; Zou, H.; Yang, L.; Le, X.C. Analysis of oxidized multi-walled carbon nanotubes in single K562 cells by capillary electrophoresis with laser-induced fluorescence. Analytical and Bioanalytical Chemistry, 387, 119-126 (2007).
120.	Guthrie, J.W.; Ryu, J.H.; Le, X.C.; WiebeLe, L.I. Characterization of a cyclodextrin-oligonucleotide complex by capillary electrophoresis using laser-induced fluorescence. Journal of Pharmacy and Pharmaceutical Sciences, 10(2), 244-253 (2007).
119.	Zhang, H.; Zhao, Q.; Le, X.C. Ultrasensitive protein detection- the use of aptamers as probes. Bioforum Europe, 11(1/2), 54-56 (2007).
2006
118.	Shen, S.; Lee, J.; Sun, X.; Wang, H.; Weinfeld, M.; Le, X.C. Elevation of cellular BPDE uptake by human cells: a possible factor contributing to co-carcinogenicity by arsenite. Environmental Health Perspectives, 114, 1832-1837 (2006).
117.	Zhang, H.; Wang, Z.; Li, X.F.; Le, X.C. Ultrasensitive detection of proteins by amplification of affinity aptamers. Angewandte Chemie International Edition, 45, 1576-1580 (2006). A Press Release about this work is available.
116.	Hamula, C.A.; Wang, Z.; Zhang, H.; Kwon, E.; Gabos, S.; Li, X.F.; Le, X.C. Chromium on the hands of children after playing in playgrounds built from chromated copper arsenate (CCA)-treated wood. Environmental Health Perspectives, 114, 460-465 (2006).
115.	Hamula, C.L.A.; Guthrie, J.W.; Zhang, H.; Li, X.-F.; Le, X.C. Selection and analytical applications of aptamers. Trends in Analytical Chemistry, 25, 681-691 (2006).
114.	Fu, H.; Guthrie, J.; Le, X.C. Study of binding stoichiometries of the human immunodeficiency virus type 1 reverse transcriptase by capillary electrophoresis and laser induced fluorescence polarization using aptamers as probes. Electrophoresis, 27, 433-441 (2006).
113.	Xiao, H.; Li, X.; Zou, H.; Yang, L.; Wang, Y.; Wang, H.; Le, X.C. CE-LIF coupled with flow cytometry for high-throughput quantitation of fluorophores in single intake cells. Electrophoresis, 27, 3452-3459 (2006).
112.	Guthrie, J.W.; Hamula, C.L.A.; Zhang, H.; Le, X.C. Assays for cytokines using aptamers. Methods, 38, 324-330 (2006).
111.	Mo J., Y. Xia, Y.; Wade, T.J.; Schmitt, M.; Le, X.C.; Dang, R.; Mumford, J.L. Chronic Arsenic Exposure and Oxidative Stress: OGG1 Expression and Arsenic Exposure, Nail Selenium, and Skin Hyperkeratosis in Inner Mongolia. Environmental Health Perspectives, 114, 835-841 (2006).
110.	Li, Y.; Xia, Y.; He, L.; Ning, Z.; Wu, K.; Zhao, B.; Le, X.C..; Kwok, R.; Schmitt, M.; Wade, T.; Mumford, J.; Otto, D. Neurosensory effects of chronic exposure to arsenic via drinking water in Inner Mongolia: Signs, symptoms and pinprick testing." Journal of Water Health, 4, 29-37 (2006).
109.	Xiao, H.; Li, X.; Zou, H.; Yang, L.; Yang, Y.; Wang, Y.; Wang, H.; Le, X.C. Immunoassay of P-glycoprotein on single cell by capillary electrophoresis with laser induced fluorescence detection. Analytica Chimica Acta, 556, 340-346 (2006).
108.	Gong, Z.; Lu, X.; Watt, C.; Wen, B.; He, B.; Mumford, J.; Ning, Z.; Xia, Y.; Le, X.C. Speciation analysis of arsenic in groundwater from Inner Mongolia with an emphasis on acid-leachable particulate arsenic. Analytical Chimica Acta, 555, 181-187 (2006).
2005
107.	Wang, H.; Lu, M.; Le, X.C. DNA-Driven focusing for protein-DNA binding assays using capillary electrophoresis. Analytical Chemistry, 77, 4985-4990 (2005).
106.	Le, X.C.; Pavski, V.; Wang, H. Affinity recognition, capillary electrophoresis and laser induced fluorescence polarization for ultrasensitive bioanalysis. Canadian Journal of Chemistry, 83, 185-194 (2005).
105.	Schmitt, M.T.; Schreinemachers, D.; Wu, K.; Ning, Z.; Zhao, B.; Le, X.C.; Mumford, J.L. Nails as a biomarker of arsenic exposure from well water in an Inner Mongolian population: Comparing atomic fluorescence spectrometry and neutron activation analysis. Biomarkers, 10, 95-104 (2005).
104.	Spiegelstein, O.; Gould, A.; Wlodarczyk, B.; Tsie, M.; Lu, X.; Le, X.C.; Troen, A.; Selhub, J.; Piedrahita, J.A.; Salbaum, J.M.; Kappen, C.; Melnyk, S.; James, S.J.; Finnell, R.H Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicology and Applied Pharmacology, 203, 18-26 (2005).
103.	Spiegelstein, O.; Lu, X.; Le, X.C.; Troen, A.; Selhub, J.; Melnyk, S.; James, S.J.; Finnell, R.H. Effects of dietary folate intake and folate binding protein-2 (FOLBP2) on urinary speciation of sodium arsenate in mice. Environmental Toxicology and Pharmacology, 19, 1-7 (2005).
102.	Watt, C; Le, X.C. Arsenic compounds in water. In Water Quality and Resource Development; Lehr, J.H., Keeley, J., Lehr, J., Eds; Water Encyclopedia; Wiley: Hoboken, NJ. 5, 7-14 (2005).
2004
101.	Lu, M.; Wang, H.; Li, X.-F.; Lu, X.; Cullen, W.R.; Arnold, L.L; Cohen, S.M.; Le, X.C. Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood. Chemical Research in Toxicology, 17, 1733-1742 (2004).
100.	Paproski, R.; Le, X.C. Boric acid assisted ion exchange chromatography for separating arsenic species. Analytical Chimica Acta, 526, 69-76 (2004).
99.	Kwon, E.; Zhang, H.; Wang, Z.; Jhangri, G.S.; Fok, N.; Gabos, S.; Li, X.F.; Le, X.C. Arsenic on the hands of children after playing in playgrounds. Environmental Health Perspectives, 112, 1375-1380 (2004).
98.	Gong, Z.; Teixeira, C.; Xing, J.; Yokota, J.; Kohno, T.; Gabos, S.; Le, X.C.; Li, X.F. Electronic microarray technique for detection of nine base substitutions including single nucleotide polymorphisms in the human OGG1 gene. Clinical Chemistry, 50, 1441-1444 (2004).
97.	Wang, Z.; Zhou, J.; Lu, X.; Gong, Z.; Le, X.C. Arsenic speciation in urine from acute promyelocytic leukemia patients undergoing arsenic trioxide treatment. Chemical Research in Toxicology, 17, 95-103 (2004).
96.	Le, X.C.; Lu, X.; Li, X.-F. Arsenic speciation. Analytical Chemistry, 76, 26A-33A (2004).
95.	Le, X.C.; Weinfeld, M. Cellular Responses to Arsenic: DNA Damage and Defense Mechanisms. Awwa Research Foundation: Denver, CO. pp.1-147 (2004).
2003
94.	Lu, X.; Arnold, L.L.; Cohen, S.M.; Cullen,W.R.; Le, X.C. Speciation of dimethylarsinous acid and trimethylarsine oxide in urine from rats fed with dimethylarsinic acid and dimercaptopropane sulfonate. Analytical Chemistry, 75, 6463-6468 (2003).
93.	Mei, N.; Lee, J.; Sun, X.; Xing, J.Z.; Hanson, J.; Le, X.C.; Weinfeld, M. Genetic predisposition to the cytotoxicity of arsenic: the role of DNA damage and ATM. FASEB Journal, 17, 2310-2312 (2003).
92.	Jiang, G.; Gong, Z; Li, X-F.; Cullen, W.R.; Le, X.C. Interaction of trivalent arsenicals with metallothionein. Chemical Research in Toxicology, 16, 873-880 (2003).
91.	Wang, H.; Lu, M.; Mei, N.; Lee, J.; Weinfeld, M.; Le, X.C. Immunoassays using capillary electrophoresis laser induced fluorescence detection for DNA adducts. Analytica Chimica Acta, 500, 13-20 (2003).
90.	Lammon, C.A.; Le, X.C.; Hood, R.D. Pretreatement with periodate-oxidized adenosine enhances the developmental toxicity of inorganic arsenic in mice. Birth Defects Research, Part B, Developmental and Reproductive Toxicology. 68, 335-343 (2003).
89.	Pavski, V.; Le, X.C. Ultrasensitive protein-DNA binding assays. Current Opinions in Biotechnology, 14, 65-73 (2003).
88.	Wang, H.; Lu, M.; Weinfeld, M.; Le, X.C. Enhancement of immunocomplex detection and application to assays for DNA adduct of benzo[a]pyrene. Analytical Chemistry, 75, 247-254 (2003).
87.	Spiegelstein, O.; Lu, X.; Le, X.C.; Troen, A.; Selhub, J.; Melnyk, S.; James, J.S.; Finnell, R.H. Effect of dietary folate intake and folate binding protin-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicology Letters, 145, 167-174 (2003).
86.	Jing, B.; Lu, X.; Le, X.C.; Yu, B. Speciation analysis of arsenic in food samples with high performance liquid chromatography inductively coupled plasma mass spectrometry. Chinese Journal of Chromatography, 21, 545-548 (2003).
85.	Jiang, G.; Lu, X.; Gong, Z.; Cullen, W.R.; Le, X.C. Trivalent arsenic species: analysis, stability, and interaction with a protein. In W.R. Chappell, C.O. Abernathy, R.L. Calderon and D.J. Thomas (Eds.), Arsenic Exposure and Health Effects, Elsevier, New York. 51-68 (2003).
84.	Cohen, S.M.; Le, X.C.; Lu, X.; Cano, M.; Arnold, L.L. Carcinogenicity of Dimethylarsinic Acid [DMA(V)]. In W.R. Chappell, C.O. Abernathy, R.L. Calderon and D.J. Thomas (Eds.), Arsenic Exposure and Health Effects, Elsevier, New York. 321-335 (2003).
83.	Spiegelstein, O.; Lu, X.; Le, X.C.; Finnell, R.H. Urinary Speciation of Sodium Arsenate in Folate Receptor Knockout Mice. In W.R. Chappell, C.O. Abernathy, R.L. Calderon and D.J. Thomas (Eds.), Arsenic Exposure and Health Effects, Elsevier, New York. 337-344 (2003).
2002
82.	Lam, M.; Le, X.C. Competitive immunoassay for vancomycin using capillary electrophoresis with laser-induced fluorescence detection. Analyst, 127, 1633-1637 (2002).
81.	Wang, H.; Xing, J.; Tan, W.; Lam, M.; Carnelley, T.; Weinfeld, M.; Le, X.C. Binding stoichiometry of DNA adducts with antibody studied by capillary electrophoresis and laser-induced fluorescence. Analytical Chemistry, 74, 3714-3719 (2002).
80.	Gong, Z.; Jiang, G.; Cullen, W.R.; Aposhian, H.V.; Le, X.C. Determination of arsenic metabolic complex excreted in human urine after administration of sodium 2,3-dimercapto-1-propane sulfonate. Chemical Research in Toxicology, 15, 1318-1323 (2002).
79.	Cohen, S.M.; Arnold, L.L.; Uzvolgyi, E.; Cano, M.; St. John, M.; Yamamoto, S.; Lu, X.; Le, X.C. Possible role of dimethylarsinous acid on dimethylarsinic acid-induced urothelial toxicity and regeneration in the rat. Chemical Research in Toxicology, 15, 1150-1157 (2002).
78.	Takao, M.;, Kanno, S,; Shiromoto, T.; Hasegawa, R.; Ide, H.; Ikeda, S.; Sarker, A.H.; Seki, S.; Xing, J.Z.; Le, X.C.; Weinfeld, M.; Kobayashi, K.; Miyazaki, J.; Muijtjens, M.; Hoeijmakers, J.H.J.; van der Horst, G.; Yasui, A. Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homologue for repair of thymine glycols. EMBO Journal, 21, 3486-3493 (2002).
77.	Le, X.C.; Wan, Q.H.; Lam, M.T. Fluorescence polarization detection for affinity capillary electrophoresis. Electrophoresis, 23, 903-908 (2002).
76.	Gong, Z.; Lu, X.; Ma, M.; Watt, C.; Le, X.C. Arsenic speciation analysis. Talanta, 58, 77-96 (2002).
75.	Lam, M.T.; Boulet, C.A.; Le, X.C. Development of a tetramethylrhodamine-labeled probe for capillary electrophoresis-based competitive immunoassay of staphylococal enterotoxin B. Analytica Chimica Acta, 457, 21-28 (2002).
74.	Xing, J.Z.; Lee, J.; Leadon, S.A.; Le,X.C.; Weinfeld, M. Immunofluorescence detection of radiation-induced DNA base damage. Military Medicine, 167 (Suppl. 1), 2-4 (2002).
73.	Karagas, M.R., Nelson, H.H.; Kelsey, K.T.; Morris, S.; Blum, J.; Tosteson, T.D.; Carey, M.; Lu, X.; Le, X.C. Urinary arsenic species in relation to drinking water, toenail arsenic concentrations and genetic polymorphisms in GSTM1 in New Hampshire. Progress in Nucleic Acid Research, Chapter 17, 251-261 (2002).
72.	Watt, C.; Le, X.C. Arsenic speciation in natural waters. In Cai, Y. (Ed). Biogeochemistry of Trace Elements. American Chemical Society Symposium Series, ACS, Washington, DC. 11-32 (2002).
2001
71.	Pavski, V.; Le, X.C. Detection of human immunodeficiency virus type 1 reverse transcriptase using aptamers as probes in affinity capillary electrophoresis. Analytical Chemistry, 73, 6070-6076 (2001).
70.	Gong, Z.; Lu, X.; Cullen, W.R.; Le, X.C. Unstable trivalent arsenic metabolites, monomethylarsonous acid and dimethylarsinous acid. Journal of Analytical Atomic Spectrometry, 16, 1409-1413 (2001).
69.	Carnelley, T.J.; Barker, S.; Tan, W.G.; Weinfeld, M.; Le, X.C. Synthesis, characterization, and applications of a fluorescent DNA damage probe. Chemical Research in Toxicology, 14, 1513-1522 (2001).
68.	Wlodarczyk, B.; Spiegelstein, O.; Waes, J.G.; Vorce, R.L.; Lu, X.; Le, X.C.; Finnell, R.H. Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 (Folbp2) knockout mice. Toxicology & Applied Pharmacology, 177, 238-246 (2001).
67.	Tian, D.; Ma, H.; Feng, Z.; Xia, Y.; Le, X.C.; Ni, Z.; Allen, J.; Collins, B.; Mumford, J.L. Micronuclei analysis in human exfoliated epithelia from the residents chronically exposed to arsenic via drinking water in Inner Mongolia, China. Journal of Toxicololgy and Environmental Health Part A, 64, 473-84 (2001).
66.	Karagas, M.R.; Le, X.C.; Morris, S.; Blum, J.; Lu, X.; Spate, V.; Carey, M.; Stannard, V.; Llaue, B.; Tosteson, T.D. Markers of low level arsenic exposure for evaluating human cancer risks in a US population. Int. J. Occupat. Med. Environ. Health, 14, 171-175 (2001).
65.	Thomas, D.J.; Del Razo, L.M.; Schreinemachers, D.M.; Hudgens, E.D.; Le, X.C.; Calderon, R.L. Dose-response relationships for the metabolism and urinary excretion of arsenicals in humans. In W.R. Chappell, C.O. Abernathy and R.L. Calderon (Eds.), Arsenic Exposure and Health Effects, Elsevier Science. pp. 353-366 (2001).
64.	Aposhian, V.H.; Gurzau, E.S.; Le, X.C.; Gurzau, A.; Zakharyan, R.A.; Cullen, W.R.; Healy, S.M.; Gonzalez-Ramirez, D.; Morgan, D.L.; Sampayo-Reyes, A.; Wildfang, E.; Radabaugh, T.R.; Petrick, J.S.; Mash, Jr. E.A.; Avala, R.B.; Aposhian, M.M. The discovery, importance and significance of monomethylarsonous acid (MMAIII) in urine of humans exposed to inorganic arsenic. In W.R. Chappell, C.O. Abernathy and R.L. Calderon (Eds.), Arsenic Exposure and Health Effects, Elsevier Science. pp. 305-314 (2001).
63.	Lu, X.; Gong, Z.; Ma, M.; Cullen, W.R.; Aposhian, H.V.; Zheng, B.; Gurzau, E.S.; Le, X.C. Speciation of human urinary arsenic including the trivalent methylation metabolites. In W.R. Chappell, C.O. Abernathy and R.L. Calderon (Eds.), Arsenic Exposure and Health Effects, Elsevier Science. pp. 339-352 (2001).
62.	Le, X.C. Speciation of arsenic in water and biological matrices. American Water Works Associaiton (AWWA) and AWWA Research Foundation, Denvor, CO. ISBN 1-58321-085-7. pp.1-145 (2001).
61.	Le, X.C. Arsenic speciation in the environment and humans. In Frankenberger, Jr, W.T. (Ed), Environmental Chemistry of Arsenic. Marcel Dekker, Inc. New York, Chapter 4, pp.95-116 (2001).
60.	Tan, W.G.; Carnelley, T.J.; Murphy, P.; Wang, H.; Lee, J.; Barker, S.; Weinfeld, M.; Le, X.C. Detection of DNA adducts of benzo[a]pyrene using immuno-electrophoresis with laser-induced fluorescence: analysis of A549 cells. Journal of Chromatography A, 924, 377-386 (2001).
59.	Weinfeld, M.; Xing, J.Z.; Lee, J.; Leadon, S.A.; Cooper, P.K.; Le, X.C. Factors influencing the removal of thymine glycol from DNA in gama-irradiated human cells. Progress in Nucleic Acid Research and Molecular Biology, 68, 139-149 (2001).
58.	Xing, J.Z.; Carnelley, T.; Lee, J.; Watson, W.; Weinfeld, M.; Le, X.C. Assay for DNA damage using immunochemical recognition and capillary electrophoresis. Methods in Molecular Biology,162/163, 419-428 (2001).
57.	Yalcin, S.; Le, X.C. Speciation of arsenic using solid phase extraction cartridges. Journal of Environmental Monitoring, 3, 81-85 (2001).
2000
56.	Wan, Q.-H.; Le, X.C. Studies of protein-DNA interactions by capillary electrophoresis laser-induced fluorescence polarization. Analytical Chemistry, 72, 5583-5589 (2000).
55.	Le, X.C.; Lu, X.; Ma, M.; Cullen, W.R.; Aposhian, V.; Zheng, B. Speciation of key arsenic metabolic intermediates in human urine. Analytical Chemistry, 72, 5172-5177 (2000).
54.	Le, X.C.; Yalcin, S.; Ma, M. Speciation of submicrogram per liter levels of arsenic in water: On-site species separation integrated with sample collection. Environmental Science & Technology, 34, 2342-2347 (2000).
53.	Le, X.C.; Ma, M.; Lu, X.; Cullen, W.R.; Aposhian, V.; Zheng, B. Determination of monomethylarsonous acid, a key arsenic methylation intermediate, in human urine. Environmental Health Perspectives, 108, 1015-1018 (2000).
52.	Le, X.C.; Weinfeld, M.; Xing, J.Z. Methods for quantitating low level modifications of nucleotide sequences. United States patent No. 6,132,968. October 17, 2000.
51.	Xing, J.Z.; Lee, J.; Leadon, S.A.; Weinfeld, M.; Le, X.C. Measuring DNA damage using capillary electrophoresis with laser induced fluorescence detection. Methods, 22, 157-163 (2000).
50.	Aposhian, V.H.; Gurzau, E.S.; Le, X.C.; Gurzau, A.; Healy, S.M.; Lu, X.; Ma, M.; Yip, L.; Zakharyan, R.A.; Maiorino, R.M.; Dart, R.C.; Gonzalez-Ramirez, D.; Morgan, D.; Avram, D.; Aposhian, M.M. Occurrence of monomethylarsonous acid in urine of humans exposed to inorganic arsenic. Chemical Research in Toxicology, 13, 693-697 (2000).
49.	Aposhian, H.V.; Zheng, B.; Aposhian, M.M.; Le, X.C.; Cebrian, M.E.; Cullen, W.R.; Zakharyan, R.A.; Ma, M.; Dart, R.C.; Cheng, Z.; Andrews, P.; Yip, L.; O'Malley, G.F.; Maiorino, .M.; Van Voorhies, W.; Healy, S.M.; Titcomb, A. DMPS-Arsenic challenge test: Modulation of arsenic species, including monomethylarsonous acid, excreted in human urine. Toxicology & Applied Pharmacology, 165, 74-83 (2000).
48.	Li, X.-F.; Ren, H.; Le, X.C.; Qi, M.; Ireland, I.; Dovichi, N.J. Migration time correction for analysis of derivatized amino acids and oligosaccharides using micellar capillary electrochromatography. Journal of Chromatography A, 869, 375-384 (2000).
47.	Ma, M.; Le, X.C.; Hu, B.; Jiang, Z.C. High performance liquid chromatography with hydride generation atomic fluorescence detection for rapid urinary arsenic speciation. Journal of Analytical Science, 16, 89-96 (2000).