| 2010 - Present |
| 2000 - 2009 |
| 1990 - 1999 |
| 1980 - 1989 |
| 1. |
Feng, W.; Peng, H.; Zhang, H.; Weinfeld, M.; Le, X.C.
A sensitive technique unravels the kinetics of activation and trans-cleavage of CRISPR-Cas systems. Angewandte Chemie International Edition, March 25, 2024. DOI: 10.1002/anie.202404069 Open Access Featured on Inside Cover (May 7, 2024) |
| 2. |
Feng, W.; Newbigging, A.M.; Tao, J.; Cao, Y.; Peng, H.; Le, C.; Wu, J.; Pang, B.; Li, J.; Tyrrell, D. L.; Zhang, H.; Le, X. C.
CRISPR technology incorporating amplification strategies: Molecular assays for nucleic acids, proteins, and small molecules. Chemical Science, 2021, 12 (13), 4683-4698. DOI: 10.1039/D0SC06973F. Open Access Featured on the back cover of Volume 12, Issue 13 (April 7, 2021) |
| 3. |
Feng, W.; Newbigging, A.M.; Le, C.; Pang, B.; Peng, H.; Cao, Y.; Wu, J.; Abbas, G.; Song, J.; Wang, D.-B.; Cui, M.; Tao, J.; Tyrrell, D. L.; Zhang, X.-E.; Zhang, H.; Le, X. C.
Molecular diagnosis of COVID-19: Challenges and research needs. Analytical Chemistry, 92, 10196-10209 (2020). DOI: 10.1021/acs.analchem.0c02060 Open Access Featured on the front cover of Volume 92, issue 15 (August 4, 2020) ACS Editors' Choice article |
| 4. |
Peng, H.; Le, C.; Wu, J.; Li, X.-F.; Zhang, H.; Le, X.C.
A genome editing nanomachine constructed with a Clustered Regularly Interspaced Short Palindromic Repeats system and activated by near-infrared illumination. ACS Nano, 14 (3), 2817-2826 (2020). DOI: 10.1021/acsnano.9b05276 Open Access |
| 5. |
Reid, M.; Le, X.C.; Zhang, H.
Exponential isothermal amplification of nucleic acids and assays for proteins, cells, small molecules, and enzyme activities – An EXPAR example. Angewandte Chemie International Edition, 57 (37), 11856-11866 (2018). DOI: 10.1002/anie.201712217 and 10.1002/ange.201712217 Open Access |
| 6. |
Peng, H.Y.; Li, X.-F.; Zhang, H.; Le, X.C.
A microRNA-initiated DNAzyme motor operating in living cells. Nature Communications, 8: 14378 (2017). DOI: 10.1038/ncomms14378 Open Access |
| 7. |
Peng, H.; Hu, B.; Liu, Q.; Li, J.; Li, X.-F.; Zhang, H.Q.; Le, X.C.
Methylated phenylarsenical metabolites discovered in chicken liver. Angewante Chemie International Edition, 56 (24), 6773-6777 (2017) DOI: 10.1002/anie.201700736 and 10.1002/ange.201700736 Open Access |
| 8. |
Yan, X.W.; Li, J.H.; Liu, Q.Q.; Peng, H.Y.; Popowich, A.; Wang, Z.X.; Li, X.-F.; Le, X.C.
p-Azidophenylarsenoxide: An arsenical "bait" for the in-situ capture and identification of cellular arsenic-binding proteins. Angewandte Chemie International Edition, 55 (45), 14051-14056 (2016). DOI: 10.1002/anie.201608006 and 10.1002/ange.201608006 Open Access |
| 9. |
Liu, Q.; Peng, H.; Lu, X.; Zuidhof, M.J.; Li, X.-F.; Le, X.C.
Arsenic species in chicken breast: temporal variations of metabolites, elimination kinetics, and residual concentrations. Environmental Health Perspectives, 124 (8), 1174-1181 (2016). DOI: 10.1289/ehp.1510530 Open Access |
| 10. |
Li, F.; Zhang, H.; Wang, Z.; Li, X.; Li, X.-F.; Le, X. C.
Dynamic DNA assemblies mediated by binding-induced DNA strand displacement. Journal of the American Chemical Society, 135 (7), 2443-2446 (2013). DOI: 10.1021/ja311990w Open Access |
| 11. |
Shen, S.; Li, X.-F.; Cullen, W.R.; Weinfeld, M.; Le, X.C.
Arsenic binding to proteins. Chemical Reviews, 113 (10), 7769-7792 (2013). DOI: 10/1021/cr300015c Open Access |
| 12. |
Zhang, H.; Li, F.; Dever, B.; Li, X.-F.; Le, X.C.
DNA-mediated homogeneous binding assays for nucleic acids and proteins. Chemical Reviews, 113 (4), 2812-2841 (2013). DOI: 10/1021/cr300340p |
2024 | |
| 365. |
Feng, W.; Peng, H.; Zhang, H.; Weinfeld, M.; Le, X.C.
A sensitive technique unravels the kinetics of activation and trans-cleavage of CRISPR-Cas systems. Angewandte Chemie International Edition, March 25, 2024. DOI: 10.1002/anie.202404069 Open Access Featured on Inside Cover (May 7, 2024) |
| 364. |
Tao, J.; Zhang, H.; Weinfeld, M.; Le, X.C.
Detection of uracil-excising DNA glycosylases in cancer cell samples using a three-dimensional DNAzyme walker. ACS Measurement Science Au, May 8, 2024 DOI: 10.1021/acsmeasuresciau.4c00011 Featured on Supplementary Cover Open Access |
| 363. |
Zhao, Y.; Zhao, X.; Duan, L.; Hou, R.; Gu, Y.; Liu, Z.; Chen, J.; Wu, F.; Yang, L.; Le, X.C.; Wang, Q.; Yan, X.
Reinvent aliphatic arsenicals as reversible covalent warheads toward targeted kinase inhibition and non-acute promyelocytic leukemia cancer treatment. Journal of Medicinal Chemistry, 2024, 67(7), 5458–5472. DOI: 10.1021/acs.jmedchem.3c02076 |
| 362. |
Hu, J.; Yan, X.; Le, X.C.
Label-free detection of biomolecules using inductively coupled plasma mass spectrometry (ICP-MS). Analytical and Bioanalytical Chemistry, 2024, 416, 2625-2640. DOI: 10.1007/s00216-023-05106-7 |
| 361. |
Kumblathan, T.; Liu, Y.; Crisol, M.; Pang, X.; Hrudey, S.E.; Le, X.C.; Li, X.-F.
Advances in wastewater analysis revealing the co-circulating viral trends of noroviruses and omicron subvariants. Science of the Total Environment, 2024, 920, 170887. DOI: 10.1016/j.scitotenv.2024.170887 Open Access |
2023 | |
| 360. |
Tao, J.; Zhang, H.; Weinfeld, M.; Le, X.C.
Development of a DNAzyme walker for the detection of APE1 in living cancer cells. Analytical Chemistry, 2023, 95 (40), 14990–14997 DOI: 10.1021/acs.analchem.3c02574 Featured with a supplementary cover of volume 95, issue 40 (October 10, 2023) Open Access |
| 359. |
Hoy, K.S.; Davydiuk, T.; Chen, X.; Lau, C.; Schofield, J.R.M.; Lu, X.; Graydon, J.A.; Mitchell, R.; Reichert, M.; Le, X.C.
Arsenic speciation in freshwater fish: Challenges and research needs. Food Quality and Safety, 2023, 7, 1–25. DOI: 10.1093/fqsafe/fyad032 |
| 358. |
Davydiuk, T.; Tao, J.; Lu, X.; Le, X.C.
Effects of dietary intake of arsenosugars and other organic arsenic species on studies of arsenic methylation efficiency in humans. Environment & Health, 2023, 1 (4), 236–248. DOI: 10.1021/envhealth.3c00090 Featured on the front cover of Volume 1, Issue 4 (October 20, 2023) Front cover Open Access |
| 357. |
Kumblathan, T.; Liu, Y.; Pang, L.; Hrudey, S.E.; Le, X.C.; Li, X.F.
Quantification and differentiation of SARS-CoV-2 variants in wastewater for surveillance. Environment & Health, 2023, 1 (3), 203–213. DOI: 10.1021/envhealth.3c00089 Open Access |
| 356. |
Liu, Y.; Kumblathan, T.; Joyce, M.A.; Tyrrell, D.L.; Tipples, G.; Pang, X.; Li, X.-F.; Le, X. C.
Multiplex assays enable simultaneous detection and identification of SARS-CoV-2 variants of concern in clinical and wastewater samples. ACS Measurement Science Au, 2023, 3 (4), 258–268. DOI: 10.1021/acsmeasuresciau.3c00005 Open Access |
| 355. |
Feng, W.; Zhang, H.; Le, X.C.
Signal amplification by the trans-cleavage activity of CRISPR-Cas systems: Kinetics and performance. Analytical Chemistry, 2023, 95 (1), 206–217. DOI: 10.1021/acs.analchem.2c04555 |
| 354. |
Xiao, H.; Hu, J.; Huang, C.; Feng, W.; Liu, Y.; Kumblathan, T.; Tao, J.; Xu, J.; Le, X.C.; Zhang, H.
CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern. Trends in Analytical Chemistry, 2023, 161, 117000. DOI: 10.1016/j.trac.2023.117000 Featured on the cover of volume 161 (April 2023). |
| 353. |
Liu, Y.; Kumblathan, T.; Tao, J.; Xu, J.; Feng, W.; Xiao, H.; Hu, J.; Huang, C.; Wu, Y.; Zhang, H.; Li, X.-F.; Le, X.C.
Recent advances in RNA sample preparation techniques for the detection of SARS-CoV-2 in saliva and gargle. Trends in Analytical Chemistry, 2023, 165, 117107. DOI: 10.1016/j.trac.2023.117107 |
| 352. |
Lau, C.; Le, X.C.
Cadmium, chromium, copper, iron, lead, mercury, nickel, and zinc in freshwater fish: Assessing trophic transfer using stable isotope ratios of d15N and d13C. Journal of Environmental Sciences, 2023, 128, 250–257. DOI: 10.1016/j.jes.2023.01.007 |
| 351. |
Kumblathan, T.; Liu, Y.; Qiu, Y.; Pang, L.; Hrudey, S.E.; Le, X.C.; Li, X.-F.
An efficient method to enhance recovery and detection of SARS-CoV-2 RNA in wastewater. Journal of Environmental Sciences, 2023, 130, 139–148. DOI: 10.1016/j.jes.2022.10.006 |
2022 | |
| 350. |
Moreno-Bondi, M.C.; Le, X.C.; Field, J.A.; Richardson, S.D.; Li, X.-F.; Diamond, M.L.; Li, X.; Goring, P.D.
From detection to remediation: Analytical science at the forefront of environmental research. Analytical Chemistry, 2022, 94 (43), 14811–14814. DOI: 10.1021/acs.analchem.2c04534 ACS Omega, 2022, 7 (43), 38105–38108. DOI: 10.1021/acsomega.2c06631 Open Access |
| 349. |
Liu, Y.; Kumblathan, T.; Feng, W.; Pang, B.; Tao, J.; Xu, J.; Xiao, H.; Joyce, M.A.; Tyrrell, D.L.; Zhang, H.; Li, X.-F.; Le, X.C.
On-site viral inactivation and RNA preservation of gargle and saliva samples combined with direct analysis of SARS-CoV-2 RNA on magnetic beads. ACS Measurement Science Au, 2022, 2 (3), 224–232. DOI: 10.1021/acsmeasuresciau.1c00057 ACS Editors' Choice article Featured on the front cover of Volume 2, Issue 3 (May/June, 2022) Open Access |
| 348. |
Deng, W.; Xu, J.Y.; Peng, H.; Huang, C.Z.; Le, X.C.; Zhang, H.
DNAzyme motor systems and logic gates facilitated by toehold exchange translators. Biosensors and Bioelectronics, 2022, 217, 114704. DOI: 10.1016/j.bios.2022.114704 |
| 347. |
Feng,W.; Xiao, H.; Yuan, A.; Deng, Z.; Wang, X.; Peng, H.; Le, X.C.
Integrating CRISPR and isothermal amplification reactions in single-tubes for ultrasensitive detection of nucleic acids: the SARS-CoV-2 RNA example. Sci. Sin. Chim., 2022, 52, 1–14. DOI: 10.1360/SSC-2022-0076 |
| 346. |
Li, Q.; Yao, J.J.; Jiang, Y.N.; Guo, X.Y.; Ying, Y.; Wen, Y.; Liu, X.L.; Wu, Y.P.; Yang, H.F.; Le, X.C.
One-step preparation of SnO2-AuNPs as nanocomposites on photoelectrodes to enhance photoelectrochemical detection of nitrite and superoxide" Journal of Electroanalytical Chemistry, 2022, 917, 116412. DOI: 10.1016/j.jelechem.2022.116412 |
| 345. |
MacDonald, A.M.; Gabos, S.; Braakman, S.; Cheperdak, L.; Lee, B.; Hrudey, S.E.; Le, X.C.; Li, X.-F.; Mandal, R.; Martin, J.W.; Schopflocher, D.; Lyon, M.E.; Cheung, P.-Y.; Ackah, F.; Graydon, J.A.; Reichert, M.; Lyon, A.W.; Jarrell, J.; Benadé, G.; Charlton, C.; Huang, D.; Bennett, M.J.; Kinniburgh, D.W.
Maternal and Child Biomonitoring Strategies and Levels of Exposure in Western Canada During the Past Fifteen Years: The Alberta Biomonitoring Program 2005–2021. International Journal of Hygiene and Environmental Health, 2022, 244, 113990. DOI: 10.1016/j.ijheh.2022.113990 |
2021 | |
| 344. |
Cao, Y.; Zhang, H.; Le, X. C.
Split locations and secondary structures of a DNAzyme critical to binding-assembled multicomponent nucleic acid enzymes for protein detection. Analytical Chemistry, 2021, 93 (47), 15712–15719. DOI: 10.1021/acs.analchem.1c03617 Open Access |
| 343. |
Feng, W.; Peng, H.; Xu, J.; Liu, Y.; Pabbaraju, K.; Tipples, G.; Joyce, M.; Saffran, H.; Tyrrell, D. L.; Babiuk, S.; Zhang, H.; Le, X. C.
Integrating reverse transcription recombinase polymerase amplification with CRISPR technology for one-tube assay of RNA. Analytical Chemistry, 2021, 93 (37), 12808-12816. DOI: 10.1021/acs.analchem.1c03456 Open Access Featured with supplementary cover of Volume 93, Issue 37 (September 21, 2021) |
| 342. |
Feng, W.; Newbigging, A.M.; Tao, J.; Cao, Y.; Peng, H.; Le, C.; Wu, J.; Pang, B.; Li, J.; Tyrrell, D. L.; Zhang, H.; Le, X. C.
CRISPR technology incorporating amplification strategies: Molecular assays for nucleic acids, proteins, and small molecules. Chemical Science, 2021, 12 (13), 4683-4698. DOI: 10.1039/D0SC06973F. Open Access Featured on the back cover of Volume 12, Issue 13 (April 7, 2021) |
| 341. |
Wu, J.; Peng, H.; Lu, X.; Lai, M.; Zhang, H.; Le, X. C.
Binding-mediated formation of ribonucleoprotein corona for efficient delivery and control of CRISPR-Cas9. Angewandte Chemie International Edition, 2021, 60 (20), 11104–11109. DOI: 10.1002/anie.202014162 Open Access |
| 340. |
Le, C.; Liu, Y.; López-Orozco, J.; Joyce, M.; Le, X. C.; Tyrrell, D. L.
A CRISPR technique incorporated with single-cell RNA sequencing for studying hepatitis B infection. Analytical Chemistry, 2021, 93 (31), 10756–10761. DOI: 10.1021/acs.analchem.1c02227 Open Access Featured with a supplementary cover of Volume 93, issue 31 (August 10, 2021) |
| 339. |
Le, X.C.
Analytical advances in detecting SARS-CoV 2 and further research needs for COVID-19 testing. Analytical Chemistry, 2021, 93 (24), 8379–8380. DOI: 10.1021/acs.analchem.1c02327 Virtual issue on OVID-19 Testing |
| 338. |
Liu, Q.Q.; Huang, C.Z.; Li, W.H.; Fang, Z.Z.; Le, X.C.
Discovery and identification of arsenolipids using a precursor-finder strategy and data-independent mass spectrometry. Environmental Science & Technology, 2021, 55 (6), 3836–3844. DOI: 10.1021/acs.est.0c07175 |
| 337. |
Cao, Y.; Wu, J.; Pang, B.; Zhang, H.; Le, X.C.
CRISPR/Cas12a-mediated gold nanoparticle aggregation for colorimetric detection of SARS-CoV-2. Chemical Communications, 2021, 57 (56), 6871-6874. DOI: 10.1039/d1cc02546e Open Access Featured on the back cover of Volume 57, Issue 56 (July 18, 2021) |
| 336. |
Tang, Y.; Gao, L.; Feng, W.; Guo, C.; Yang, Q.; Li, F.*; Le, X.C.
The CRISPR-Cas toolbox for analytial and diagnostic assay development. Chemical Society Reviews, 2021, 50 (21), 11844-11869. DOI: 10.1039/d1cs00098e Open Access Featured on the inside front cover of Volume 50, Issue 21 (November 7, 2021) |
| 335. |
Zhou, J.R.; Kaur, G.; Ma, Y.; Arutyunov, D.; Lu, X.; Le, X.C.; Leslie, E.M.
Biliary excretion of arsenic by numan HepaRG cells is stimulated by selenide and mediated by the multidrug resistance protein 2 (MRP2/ABCC2). Biochemical Pharmacology, 2021, 193, 114799. DOI: 10.1016/j.bcp.2021.114799 Open Access |
| 334. |
Fu, Z.; Rais, Y.; Tarek A. Bismar, T.A.; Hyndman, M.E.; Le, X.C.; Drabovich, A.P.
Mapping isoform abundance and interactome of the endogenous TMPRSS2-ERG fusion protein by orthogonal immunoprecipitation-mass spectrometry assays. Molecular & Cellular Proteomics, 2021, 20, 100075. DOI: 10.1016/j.mcpro.2021.100075 Open Access |
| 333. |
Qu, X.F.; Deng, X.Y.; Pang, Y.C.; Wang, W.L.; Feng, Y.W.; Xu, Z.H.; Zhang, Y.; Le, X.C.
Recent advances in structural improvements and chemical modifications of lateral flow assay devices. Scientia Sinica Chimica, 2021, 51 (7), 905–918 DOI: 10.1360/SSC-2021-0025 |
| 332. |
Li, Z.; Chen, B.W.; Li, Y.B.; Le, X.C.
Reduction of mercury emissions from anthropogenic sources including coal combustion. Journal of Environmental Sciences, 2021, 100, 363–268. DOI: 10.1016/j.jes.2020.11.002 |
| 331. |
Pang, B; Zhang, H.; Tyrrell, D.L.; Le, X.C.
Isothermal amplification and ambient visualization in a single tube for the detection of SARS-CoV-2 using loop-mediated amplification and CRISPR technology. United States patent US 7/519,670 Filed on November 5, 2021. |
| 330. |
Le, X.C.; Zhang, H.; Peng, H.; Li, X.-F.
A microRNA initiated DNAzyme motor operating in living cells. United States patent 10,934,162 B2. Issued on March 2, 2021. |
2020 | |
| 329. |
Pang, B.; Xu, J.; Liu, Y.; Peng, H.; Feng, W.; Cao, Y.; Wu, J.; Xiao, H.; Pabbaraju, K.; Tipples, G.; Joyce, M.A.; Saffran, H.A.; Tyrrell, D. L.; Zhang, H.; Le, X. C.
Isothermal amplification and ambient visualization in a single tube for the detection of SARS-CoV-2 using loop-mediated amplification and CRISPR technology. Analytical Chemistry, 2020, 92, 16204–16212. DOI: 10.1021/acs.analchem.0c04047 Open Access |
| 328. |
Feng, W.; Newbigging, A.M.; Le, C.; Pang, B.; Peng, H.; Cao, Y.; Wu, J.; Abbas, G.; Song, J.; Wang, D.-B.; Cui, M.; Tao, J.; Tyrrell, D. L.; Zhang, X.-E.; Zhang, H.; Le, X. C.
Molecular diagnosis of COVID-19: Challenges and research needs. Analytical Chemistry, 2020, 92 (15), 10196-10209. DOI: 10.1021/acs.analchem.0c02060 Open Access Featured on the front cover of Volume 92, issue 15 (August 4, 2020) ACS Editors' Choice article |
| 327. |
Liu, Y.; Le, C.; Tyrrell, D.L.; Le, X.C.; Li, X.-F.
Aptamer binding assay for the E antigen of hepatitis B using modified aptamers with G-quadruplex structures. Analytical Chemistry, 2020, 92 (9), 6495-6501. DOI: 10.1021/acs.analchem.9b05740 Open Access |
| 326. |
Peng, H.; Le, C.; Wu, J.; Li, X.-F.; Zhang, H.; Le, X.C.
A genome editing nanomachine constructed with a Clustered Regularly Interspaced Short Palindromic Repeats system and activated by near-infrared illumination. ACS Nano, 2020, 14 (3), 2817-2826. DOI: 10.1021/acsnano.9b05276 Open Access |
| 325. |
Peng, H.; Newbigging, A.M.; Reid, M.S.; Uppal, J.S.; Xu, J.Y.; Zhang, H.; Le, X.C.
Signal amplification in living cells: A review of microRNA detection and imaging. Analytical Chemistry, 92 (1), 292-308. DOI: 10.1021/acs.analchem.9b04752 Open Access |
| 324. |
Zhao, Q.; Tao, J.; Feng, W.; Uppal, J.S.; Peng, H.; Le, X.C.
Aptamer binding assays and molecular interaction studies using fluorescence anisotropy - A review. Analytica Chimica Acta , 2020, 1125, 267-278. DOI: 10.1016/j.aca.2020.05.061 Invited reveiw |
| 323. |
Liu, Q.; Huang, C.Z.; Le, X.C.
Arsenic species in electronic cigarettes: Determination and potential health risk. Journal of Environmental Sciences, 2020, 91, 168-176. DOI: 10.1016/j.jes.2020.01.023 Open Access |
| 322. |
Reid, M.S.; Hoy, K.S.; Uppal, J.S.; Schofield, J.R.M.; Lin, Y.; Lu, X.; Peng, H.; Le. X.C.
Arsenic speciation analysis: A review with an emphasis on chromatographic separations. Trends in Analytical Chemistry, 2020, 123, 115770. DOI: 10.1016/j.trac.2019.115770 Open Access |
| 321. |
Huang K., Gao, F.; Le, X.C.; Zhao, F.-J.
N-Hydroxyarylamine O-acetyltransferases 1 ENhoAs catalyze acetylation of 3-amino-4-hydroxyphenylarsonic acid in the 4-hydroxy-3-nitrobenzenearsonic acid (Roxarsone) transformation pathway of Enterobacter sp. CZ-1. Applied and Environmental Microbiology, 2020, 86 (2), e02050-19. DOI: 10.1128/AEM.02050-19 |
| 320. |
Davydiuk, T.; Chen, X.J.; Huang, L.J.; Shuai, Q.; Le, X.C.
Removal of inorganic arsenic from water using metal organic frameworks. Journal of Environmental Sciences, 2020, 97, 162-168. DOI: 10.1016/j.jes.2020.08.012 |
| 319. |
Xie, J.J.; Schofield, J.R.M.; Liao, L.J.; Peng, H.Y.; Uppal, J.S.; Zheng, Q.; Le, X.C.
Simultaneous removal of arsenic and antimony from mining wastewater. Journal of Environmental Sciences, 2020, 93, 117-119. DOI: 10.1016/j.jes.2020.04.003 |
| 318. |
Deng, W.C.; Schofield, J.R.M.; Le, X.C.; Li, X.-F.
Electronic cigarettes and toxic substances, including arsenic species. Journal of Environmental Sciences, 2020, 92, 278-283. DOI: 10.1016/j.jes.2020.03.004 |
| 317. |
Chen, J.; Moe, B.; Zhu, L.Z.; Le, X.C.
“Waste”-ing away: Presence of Cu ions influences microbial degradation kinetics and metabolite formation of the prevalent brominated flame retardant BDE-47. Journal of Environmental Sciences, 2020, 87, 421-424. DOI: 10.1016/j.jes.2019.10.002 |
| 316. |
Le, X.C.; Zhang, H.; Newbigging, A.N.
Beacon-mediated Exponential Amplification Reaction (BEAR) Using a Single Enzyme and Primer. United States patent application, US 16/883,734. |
| 315. |
Peng, H.; Zhang, H.; Li, X.-F.; Le, X.C.
Near-Infrared photothermally activated CRISPR/Cas9 genome editing machine. United States provisional patent application. United States patent application, US 62/899,927. |
2019 | |
| 314. |
Newbigging, A.M.; Zhang, H.; Le, X.C.
Beacon-mediated exponential amplification reaction (BEAR) using a single enzyme and primer. Chemical Communications, 2019, 55, 10677–10680. DOI: 10.1039/c9cc04226a Open Access |
| 313. |
Zhao, Q.; Tao, J.; Uppal, J.S.; Peng, H.Y.; Wang, H.L.; Le, X.C.
Nucleic acid aptamers improving fluorescence anisotropy and fluorescence polarization assays for small molecules. TrAC - Trends in Analytical Chemistry, 2019, 110, 401-409. DOI: 10.1016/j.trac.2018.11.018 |
| 312. |
Huang K., Peng, H.Y.; Gao, F.; Liu, Q.Q.; Lu, X.; Shen, Q.R.; Le, X.C.; Zhao, F.-J.
Biotransformation of arsenic-containing Roxarsone by an aerobic soil bacterium Enterobacter sp. CZ-1. Environmental Pollution, 2019, 247, 482-487. DOI: 10.1016/j.envpol.2019.01.076 |
| 311. |
Chen, J.; Le, X.C.; Zhu, L.Z.
Metabolomics and transcriptomics reveal defense mechanism of rice (Oryza sativa) grains under stress of 2,2’,4,4’-tetrabromodiphenyl ether. Environment International, 2019, 133, 105154. DOI: 10.1016/j.envint.2019.105154 Open Access |
| 310. |
Uppal, J.S.; Zheng, Q.; Le, X.C.
Arsenic in drinking water - Recent examples and updates from Southeast Asia. Current Opinion in Environmental Science & Health, 2019, 7, 126-135. DOI: 10.1016/j.coesh.2019.01.004 |
| 309. |
Feng, W.; Yan, X.W.; Le, X.C.
Effects of metal contamination on ammonia-oxidizing microorganisms in a freshwater reservoir. Journal of Environmental Sciences, 2019, 79, 364-366. DOI: 10.1016/j.jes.2019.02.005 |
| 308. |
Hoy, K.S.; Uppal, J.S.; Le, X.C.
Effect of root anatomy and apoplastic barrier development on cadmium uptake in rice. Journal of Environmental Sciences, 2019, 79, 361-363. DOI: 10.1016/j.jes.2019.02.004 |
| 307. |
Uppal, J.S.; Zheng, Q.; Le, X.C.
An improved and simple method for removal of arsenic from drinking water. Journal of Environmental Sciences, 2019, 76, 415-417. DOI: 10.1016/j.jes.2018.11.017 |
| 306. |
Yan, X.; Le, X.C.
Fluorescence imaging of Cu(I) in endoplasmic reticulum of live cells and tissue. Science China Chemistry, 2019, 62, 887–888. DOI: 10.1007/s11426-019-9500-6 |
2018 | |
| 305. |
Reid, M.; Le, X.C.; Zhang, H.
Exponential isothermal amplification of nucleic acids and assays for proteins, cells, small molecules, and enzyme activities – An EXPAR example. Angewandte Chemie International Edition, 2018, 57 (37), 11856-11866. DOI: 10.1002/anie.201712217 and 10.1002/ange.201712217 Open Access |
| 304. |
Reid, M.S.; Paliwoda, R.E.; Zhang, H.; Le, X. C.
Reduction of background generated from template-template hybridizations in the Exponential Amplification Reaction. Analytical Chemistry, 2018, 90 (18), 11033-11039. DOI: 10.1021/acs.analchem.8b02788 Open Access |
| 303. |
Peng, H.Y.; Newbigging, A.M.; Wang, Z.X.; Tao, J.; Deng, W.C.; Le, X.C.; Zhang, H.Q.
DNAzyme-mediated assays for amplified detection of nucleic acids and proteins. Analytical Chemistry, 2018, 90 (1), 190-207. DOI: 10.1021/acs.analchem.7b04926 Open Access |
| 302. |
Li, F.; Lin, Y.W.; Lau, A.; Tang, Y.; Chen, J.; Le, X.C.
Binding-induced molecular amplifier as a universal detection platform for biomolecules and biomolecular interaction. Analytical Chemistry, 2018, 90 (14), 8651-8657. DOI: DOI: 10.1021/acs.analchem.8b01985 |
| 301. |
Yan, X.; Le, X.C.; Zhang, H.
Antibody-bridged beacon for homogeneous detection of small molecules. Analytical Chemistry, 2018, 90 (16), 9667–9672. DOI: 10.1021/acs.analchem.8b02510 |
| 300. |
Yan, X.; Zhang, H.; Wang, Z.; Peng, H.; Tao, J.; Li, X.-F.; Le, X.C.
Quantitative synthesis of DNA-protein conjugates with 1:1 stoichiometry. Chemical Communications, 2018, 54, 7491-7494. DOI: 10.1039/c8cc03268h |
| 299. |
Xu, L.; Zhang, H.Q.; Yan, X.W.; Peng, H.Y.; Wang, Z.X.; Zhang, Q.; Li, P.W.; Zhang, Z.W.; Le, X.C.
Binding-induced DNA dissociation assay for small molecules: sensing aflatoxin B1. ACS Sensors, 2018, 3, 2590-2596. DOI: DOI: 10.1021/acssensors.8b00975 |
| 298. |
Liu, Q.; Lu, X.; Peng, H.; Popowich, A.; Tao, J.; Uppal, J.S.; Yan, X.; Boe, D.; Le, X.C.
Speciation of arsenic – a review of phenylarsenicals and related arsenic metabolites. Trends in Analytical Chemistry (TrAC), 2018, 104, 171-182. DOI: 10.1016/j.trac.2017.10.006 |
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Chen, B.W.; Cao, F.L.; Lu, X.; Shen, S.W.; Zhou, J.; Le, X.C.
Arsenic speciation in hair and nails of acute promyelocytic leukemia (APL) patients undergoing arsenic trioxide treatment. Talanta, 2018, 184, 446-451. DOI: 10.1016/j.talanta.2018.03.021 |
| 296. |
Banerjee, M.; Kaur, G.; Whitlock, B.D.; Carew, M.W.; Le, X.C.; Leslie, E.M.
Multidrug Resistance Protein 1 (MRP1/ABCC1)-mediated cellular protection and transport of methylated arsenic metabolites differs between human cell lines. Drug Metabolism and Disposition , 2018, 46,1096–1105. DOI: 10.1124/dmd.117.079640 |
| 295. |
Liu, Q.; Leslie, E.; Moe, B.; Zhang, H.; Douglas, D.; Kneteman, N.; Le, X.C.
Metabolism of a phenylarsenical in human hepatic cells and identification of a new arsenic metabolite. Environmental Science & Technology, 2018, 52, 1386-1392. DOI: 10.1021/acs.est.7b05081 Open Access |
| 294. |
Wang, W.; Qian, Y.C.; Li, J.H.; Aljuhani, N.; Siraki, A.; Le, X. C.; Li, X.-F.
Characterization of mechanisms of glutathione conjugation with halobenzoquinones in solution and HepG2 cells. Environmental Science & Technology, 2018, 52, 2898-2908. DOI: 10.1021/acs.est.7b05945 |
| 293. |
Gupta, S.K.; Le, X.C.; Kachanosky, G.; Zuidfhof, M.J.; Siddique, T.
Transfer of arsenic from poultry feed to poultry litter: A mass balance study. Science of the Total Environment, 2018, 630, 302–307. DOI: 10.1016/j.scitotenv.2018.02.123 |
| 292. |
Chen, J.; Li, K.L.; Le, X.C.; Zhu, L.Z.
Metabolomic analysis of two rice (Oryza sativa) varieties exposed to 2, 2', 4, 4'-tetrabromodiphenyl ether. Environmental Pollution , 2018, 237, 308-317. DOI: 10.1016/j.envpol.2018.02.027 |
| 291. |
Pan, L.L.; Sun, J.T.; Le, X.C.; Zhu, L.Z.
Effect of copper on the translocation and transformation of polychlorinated biphenyls in rice. Chemosphere, 2018, 193, 514-520. DOI: 10.1016/j.chemosphere.2017.11.054 |
| 290. |
Cheng, Y.; Yang, C.; Luo, D.; Li, X.; Le, X.C.; Rong, J.
N-Propargyl caffeamide skews macrophages towards a resolving M2-like phenotype against myocardial ischemic injury via activating Nrf2/HO-1 pathway and inhibiting NF-?B pathway. Cellular Physiology and Biochemistry, 2018, 47 (6), 2544-2557. DOI: 10.1159/000491651 Open Access |
| 289. |
Hoy, K.S.; Feng, W.; Le, X.C.
Microbial methylation of mercury in the water-level fluctuation zone of the Three Gorges Reservoir, China. Journal of Environmental Sciences, 2018, 68, 218-220. DOI: 10.1016/j.jes.2018.05.021 |
| 288. |
Uppal, J.S.; Zheng, Q.; Le, X.C.
Maternal exposure to specific perfluoroalkyl substances is associated with increasing blood glucose in pregnant women. Journal of Environmental Sciences, 2018, 69, 1-2. DOI: 10.1016/j.jes.2018.06.008 |
| 287. |
Uppal, J.S.; Li, X.-F.; Le, X.C.
Visualization of fingerprints made easy with dye solution on cellulose membrane. Science China Chemistry, 2018, 61 (4), 375-376. DOI: 10.1007/s11426-018-9213-x Open Access |
| 286. |
Zhang, H.; Le, X.C.; Li, X.-F.
Binding-induced DNA nanomachines. United States Patent No. US 10,155,797 B2 Issued on December 18, 2018. |
| 285. |
Le, X.C.; Zhang, H.; Li, X.F.
Binding-induced hairpin detection system. Canadian Patent No. CA 2,772,123 Issued on March 6, 2018. |
2017 | |
| 284. |
Peng, H.Y.; Li, X.-F.; Zhang, H.; Le, X.C.
A microRNA-initiated DNAzyme motor operating in living cells. Nature Communications, 2017, 8, 14378. DOI: 10.1038/ncomms14378 Highlighted in Genetic Engineering & Biotechnology News (March 7, 2017). Open Access |
| 283. |
Zhao, B., Zhang, D., Li, C.; Yuan, Z.; Yu, F.; Zhong, S.; Jiang, G.; Yang, Y.-G.; Le, X.C.; Weinfeld, M.; Zhu, P.; Wang, H.
ATPase activity tightly regulates RecA nucleofilaments to promote homologous recombination. Cell Discovery, 2017, 3, 16053. DOI:10.1038/celldisc.2016.53 Open Access |
| 282. |
Peng, H.; Hu, B.; Liu, Q.; Li, J.; Li, X.-F.; Zhang, H.Q.; Le, X.C.
Methylated phenylarsenical metabolites discovered in chicken liver. Angewante Chemie International Edition, 2017, 56, 6773-6777. DOI: 10.1002/anie.201700736 and 10.1002/ange.201700736 Featured on the front cover of issue 24 of Angew. Chem. Int. Ed. Highlighted in Chemical & Engineering News (page 13, May 15, 2017). Open Access |
| 281. |
Li, F.; Li, J.; Tang, Y.; Wang, C.; Li, X.-F.; Le, X.C.
Targeted enlargement of aptamer functionalized gold nanoparticles for quantitative protein analysis. Proteomes, 2017, 5 (1), 1. DOI:10.3390/proteomes5010001 Open Access |
| 280. |
Zhang, Y.-K.; Dai, C.; Yuan, C.-G.; Wu, H.-C.; Xiao, Z.; Lei, Z.-N.; Yang, D.-H.; Le, X.C.; Fu, L.; Chen, Z.-S. Establishment and characterization of arsenic trioxide resistant KB/ATO cells. Acta Pharmaceutica Sinica B, 2017, 7 (5), 564-570. DOI: 10.1016/j.apsb.2017.04.001 Open Access |
| 279. |
Wu, B.; Zhu, L.; Le, X.C. Metabolomics analysis of TiO2 nanoparticles induced toxicological effects on rice (Oryza sativa L.). Environmental Pollution, 2017, 230, 302-310. DOI: 10.1016/j.envpol.2017.06.062 |
| 278. |
Uppal, J.S.; Qin, S.; Li, Z.; Le, X.C. Arsenic biotransformation and an arsenite S-adenosylmethionine methyltransferase in plankton. Journal of Environmental Sciences, 2017, 61, 118-121. DOI: 10.1016/j.jes.2017.11.010 |
| 277. |
Zheng, Q.; Blackstock, L.K.J.; Deng, W.; Wang, H.; Le, X.C.; Li, X.-F.
Commentary: Keep swimming but stop peeing in the pools. Journal of Environmental Sciences, 2017, 53, 322-325. DOI: 10.1016/j.jes.2017.03.006 |
| 276. |
Zhang, H.; Le, X.C.; Li, X.-F. Binding-induced DNA nanomachines. United States patent application No: 15/262,737, Publication number: US20170073682 A1. Publication date: March 16, 2017. |
2016 | |
| 275. |
Yan, X.W.; Li, J.H.; Liu, Q.Q.; Peng, H.Y.; Popowich, A.; Wang, Z.X.; Li, X.-F.; Le, X.C.
p-Azidophenylarsenoxide: An arsenical "bait" for the in-situ capture and identification of cellular arsenic-binding proteins. Angewandte Chemie International Edition, 55, 14051-14056 (2016). DOI: 10.1002/anie.201608006 and 10.1002/ange.201608006. Open Access |
| 274. |
Liu, Q.; Peng, H.; Lu, X.; Zuidhof, M.J.; Li, X.-F.; Le, X.C.
Arsenic species in chicken breast: temporal variations of metabolites, elimination kinetics, and residual concentrations. Environmental Health Perspectives, 124 (8), 1174- 1181 (2016). DOI: 10.1289/ehp.1510530 Open Access |
| 273. |
Liu, Q.; Leslie, E.M.; Le, X.C.
Accumulation and transport of Roxarsone, arsenobetaine, and inorganic arsenic using the human immortalized Caco-2 cell line. Journal of Agricultural and Food Chemistry, 64 (46), 8902-8908 (2016). DOI: 10.1021/acs.jafc.6b03341 Open Access |
| 272. |
Yang, Z.L.; Peng, H.Y.; Lu, X.F.; Liu, Q.; Huang, R.F.; Hu, B.; Kachanoski, G.; Zuidhof, M.J.; Le, X.C.
Arsenic metabolites, including N-acetyl-4-hydroxy-m-arsanilic acid, in chicken litter from a Roxarsone-feeding study involving 1600 chickens. Environmental Science & Technology, 50 (13), 6737-6743 (2016). DOI: 10.1021/acs.est.5b05619 Open Access |
| 271. |
Hudgens, E.E.; Drobna, Z.; He, B.; Le, X.C.; Styblo, M.; Rogers; J.; Thomas, D.J.
Biological and behavioral factors modify urinary arsenic metabolic profiles in a U.S. population. Environmental Health, 15: 62 (2016). DOI: 10.1186/s12940-016-0144-x Open Access |
| 270. |
Popowich A.; Zhang, Q.; Le, X.C.
Arsenobetaine: The ongoing mystery. National Science Review, 3 (4), 451-458 (2016). DOI: 10.1093/nsr/nww061 Open Access |
| 269. |
Zhang, Q.; Vakili, M.R.; Li, X.-F.; Lavasanifar, A.; Le, X.C.
Terpolymer micelles for the delivery of arsenic to breast cancer cells: The effect of chain sequence on polymeric micellar characteristics and cancer cell uptake. Molecular Pharmaceutics, 13 (12), 4021-4033 (2016). DOI: 10.1021/acs.molpharmaceut.6b00362 Open Access |
| 268. |
Banerjee, M.; Marensi, V.; Conseil, G.; Le, X.C.; Cole, S.P.C.; Leslie, E.M.
Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions. Biochemical Pharmacology, 120, 72-82 (2016). DOI: 10.1016.bcp.2016.09.016 |
| 267. |
Chen, B.; Lu, X.; Arnold, L.L.; Cohen, S.M.; Le, X.C.
Identification of methylated dithioarsenicals in the urine of rats fed with sodium arsenite. Chemical Research in Toxicology, 29 (9), 1480-1487 (2016). DOI: 10.1021/acs.chemrestox.6b00151 Open Access |
| 266. |
Moe, B.; Yuan, C.G.; Li, J.H.; Du, H.Y.; Gabos, S.; Le, X.C.; Li, X.-F.
Real-time cell-electronic sensing of coal fly ash particulate matter for toxicity-based air quality monitoring. Chemical Research in Toxicology, 29 (6), 972-980 (2016). DOI:10.1021/acs.chemrestox.6b00004 Open Access |
| 265. |
Moe, B.; Peng, H.Y.; Lu, X.F.; Chen, B.W.; Chen, L.W.L.; Gabos, S.; Li, X.-F.; Le, X.C.
Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing. Journal of Environmental Sciences, 49, 113-124 (2016). DOI: 10.1016/j.jes.2016.10.004 |
| 264. |
Cullen, W.R.; Liu, Q.; Lu, X.; McKnight-Whitford, A.; Peng, H.; Popowich, A.; Yan, X.; Zhang, Q.; Fricke, M.; Sun, H.; Le, X.C.
Methylated and thiolated arsenic species for environmental and health research - a review on synthesis and characterization. Journal of Environmental Sciences, 49, 7-27 (2016). DOI: 10.1016/j.jes.2016.11.004 |
| 263. |
Le, X.C.
Professor William R. Cullen and arsenic chemistry. Journal of Environmental Sciences, 49, 1-6 (2016). DOI: 10.1016/j.jes.2016.11.001 |
| 262. |
Li, F.; Tang, Y.; Traynor, S.M.; Li, X.-F.; Le, X.C.
Kinetics of proximity-induced intramolecular DNA strand displacement. Analytical Chemistry, 88 (16), 8152-8157 (2016). DOI: 10.1021/acs.analchem.6b01900 |
| 261. |
Hamula, C.L.A.; Peng, H.Y.; Wang, Z.X.; Tyrrell, G.J.; Li, X.-F.; Le, X.C.
An improved SELEX technique for selection of DNA aptamers binding to M-type 11 of Streptococcus pyogenes. Methods, 97, 51-57 (2016). DOI: 10.1016/j.ymeth.2015.12.005 |
| 260. |
Chen, J.; Deng, D.; Wu, P.; Li, F.; Li, X.-F.; Le, X.C.; Zhang, H.; Hou, X.
Amplified binding-induced homogeneous assay through catalytic cycling of analytes for ultrasensitive protein detection. Chemical Communication, 52 (9), 1816-1819 (2016). DOI: 10.1039/C5CC08879H |
| 259. |
Tao, J.; Sun, L.X.J.; Le, X.C.
Study of the effects of bisphenol A using human fetal lung fibroblasts. Journal of Environmental Sciences, 48, 6-10 (2016). DOI: 10.1016/j.jes.2016.09.001 |
| 258. |
Feng, Q., Liu, S., Mao, Z., Xu, J., Wang, Z., Le, X.C.
Cover features and new Associate Editors of the Journal of Environmental Sciences. Journal of Environmental Sciences, 48, 1-6 (2016). DOI: 10.1016/j.jes.2016.09.003 |
| 257. |
Feng, Q., Liu, S., Mao, Z., Xu, J., Wang, Z., Le, X.C.
Highlights and new Editorial Advisory Board members of the Journal of Environmental Sciences. Journal of Environmental Sciences, 47, 1-6 (2016). DOI: 10.1016/j.jes.2016.08.003 |
| 256. |
Zheng, Q.; Yang, X.Q.; Deng, W.C.; Le, X.C.; Li, X.-F.
Characterization of natural organic matter in water for optimizing water treatment and minimizing disinfection by-product formation. Journal of Environmental Sciences, 42, 1-5 (2016). DOI:10.1016/j.jes.2016.03.005 |
| 255. |
Paliwoda, R.E.; Newbigging, A.M.; Wang, Z.X.; Le, X.C.
Benefits and risks associated with consumption of Great Lakes fish containing omega-3 fatty acids and polychlorinated biphenyls (PCBs). Journal of Environmental Sciences, 41, 1-5 (2016). DOI:10.1016/j.jes.2015.12.002 |
| 254. |
Jiang, G.B.; Wang, C.X.; Le, X.C.
Rapid growth of environmental research in China. Journal of Environmental Sciences, 39, 1-3 (2016). DOI:10.1016/j.jes.2015.11.001 |
2015 | |
| 253. |
Zhang, H.Q.; Lai, M.D.; Zuehlke, A.; Peng, H.Y.; Li, X.-F.; Le, X.C.
Binding-induced DNA nanomachines triggered by proteins and nucleic acids. Angewante Chemie International Edition, 54 (48), 14326-14330 (2015). |
| 252. |
Li, F.; Zhang, H.Q.; Wang, Z.X.; Newbigging, A.M.; Reid, M.S.; Li, X.-F.; Le, X.C.
Aptamers facilitating amplified detection of biomolecules. Analytical Chemistry, 87, 274-292 (2015). Open Access |
| 251. |
Hamula, C.L.A.; Peng, H.Y.; Wang, Z.X.; Newbigging, A.M.; Tyrrell, G.J.; Li, X.-F.; Le, X.C.
The effects of SELEX conditions on the resultant aptamer pools in the selection of aptamers binding to bacterial cells. Journal of Molecular Evolution, 81, 194-209 (2015). |
| 250. |
Liu, Q.; Peng, H.Y.; Lu, X.F.; Le, X.C.
Enzyme-assisted extraction and liquid chromatography mass spectrometry for the determination of arsenic species in chicken meat. Analytica Chimica Acta, 888, 1-9 (2015). Front cover |
| 249. |
Chen, B.; Liu, Q.; Popowich, A.; Shen, S.W.; Yan, X.W.; Zhang, Q.; Li, X.-F.; Weinfeld, M.; Cullen, W.R.; Le, X.C.
Therapeutic and analytical applications of arsenic binding to proteins. Metallomics, 7, 39-55 (2015). Front cover and Open Access |
| 248. |
Roggenbeck, B.A.; Carew, M.W.; Charrois, G.J.; Douglas, D.N.; Kneteman, N.M.; Lu, X.; Le, X.C.; Leslie, E.M.
Characterization of arsenic hepatobiliary transport using sandwich cultured human hepatocytes. Toxicological Sciences, 145 (2), 307-320 (2015). Open Access |
| 247. |
Wade, T.J.; Xia, Y.; Mumford, J.; Wu, K.; Le, X.C.; Sams, E.; Sanders, W.E.
Cardiovascular disease and arsenic exposure in Inner Mongolia, China: a Case control study. Environmental Health, 14:35 (2015). Open Access |
| 246. |
Tang, Y.N.; Wang, Z.X., Chen, J.B.; Liu, L.N.; Zhao, W.A.; Le, X.C.; Li, F.
Construct real-time, wash-free, and reiterative sensors for cell surface proteins using binding-induced dynamic DNA assembly. Chemical Science, 6, 5729-5733 (2015). |
| 245. |
Tang, Y.N.; Lin, Y.W.; Yang, X.L.; Wang, Z.X.; Le, X. C.; Li, F.
A universal strategy to engineer catalytic DNA hairpin assemblies for protein analysis. Analytical Chemistry, 87(16), 8063-8066 (2015). |
| 244. |
Yang, C.B.; Zhao, J.; Cheng, Y.Y.; Le, X. C/; Rong, J.H.
N-Propargyl caffeate amide (PACA) potentiates nerve growth factor (NGF)-induced neurite outgrowth and attenuates 6-hydroxydopamine (6-OHDA)-induced toxicity via activating the Nrf2/HO-1 pathway. ACS Chemical Neuroscience, 6(9), 1560-1569 (2015). |
| 243. |
Cheng, Y.Y.; Zhao, J.; Wei, L.; Tse, H.T.; Le, X.C.; Rong, J.H.
Plant natural products calycosin and gallic acid synergistically attenuate neutrophil infiltration and subsequent injury in isoproterenol-induced myocardial infarction: a possible role for leukotriene B4 12-hydroxydehydrogenase? Oxidative Medicine and Cellular Longevity, 2015, Article ID 434052. DOI: 10.1155/2015/434052 Open Access |
| 242. |
Peng, H.; Reid, M.S.; Le, X.C.
Consumption of rice and fish in an electronic waste recycling area contributes significantly to total daily intake of mercury. Journal of Environmental Sciences, 38, 83-86 (2015). |
| 241. |
Popowich, A.; Zhang, Q.; Le, X.C.
Removal of nanoparticles by coagulation. Journal of Environmental Sciences, 38, 168-171 (2015). |
| 240. |
Newbigging, A.M.; Yan, X.; Le, X.C.
Cadmium in soybeans and the relevance to human exposure. Journal of Environmental Sciences, 37, 157-162 (2015). |
| 239. |
Li, J.H.; Fu, K.Z.; Vemula, S.; Le, X.C.; Li, X.-F.
Studying developmental neurotoxic effects of bisphenol A (BPA) using embryonic stem cells. Journal of Environmental Sciences, 36, 173-177 (2015). |
| 238. |
Zheng, Q.; Zhou, M.; Deng, W.C.; Le, X.C.
Is there a silver lining? Aggregation and photo-transformation of silver nanoparticles in environmental waters. Journal of Environmental Sciences, 34, 259-262 (2015). |
| 237. |
Fu, K.Z.; Moe, B.; Li, X.-F.; Le, X.C.
Cyanobacterial bloom dynamics in Lake Taihu. Journal of Environmental Sciences, 32, 249-251 (2015). |
| 236. |
Liu, Q.; Le, X.C.
Genotoxic effects of microcystins mediated by nitric oxide and mitochondria . Journal of Environmental Sciences, 31, 206-208 (2015). |
| 235. |
Newbigging, A.M.; Paliwoda, R.E.; Le, X.C.
Rice: Reducing arsenic content by controlling water irrigation. Journal of Environmental Sciences, 30, 129-131 (2015). |
| 234. |
Wang, Y.; Le, X.C.
Analytical methods in toxicology. Chemical Research in Toxicology, 28, 1 (2015). |
| 233. |
Li, X.F.; Liu, Y.; Le, X.C.
Apparatus and method for single-cycle selection of aptamers. U.S. Patent No. 9,150,866. Issued on October 6, 2015.. |
| 232. |
Le, X.C.; Zhang, H.; Li, X.F.
Binding-induced hairpin detection system. U.S. Patent 9,176,123 B2. Issued on November 3, 2015. |
2014 | |
| 231. |
Paliwoda, R.E.; Li, F.; Reid, M.S.; Lin, Y.; Le, X.C.
Sequential strand displacement beacon for detection of DNA coverage on functionalized gold nanoparticles. Analytical Chemistry, 86, 6138-6143 (2014). |
| 230. |
Jensen-Fontaine, M.; Norwood, W.; Dixon, G.; Brown, M.; Le, X. C.
Uptake and speciation of vanadium in the benthic invertebrate Hyalella Azteca. Environmental Science & Technology, 48, 731-738 (2014). |
| 229. |
Zhang, Q.; Vakili, M.R.; Li, X.-F.; Lavasanifar, A.; Le, X.C.
Polymeric micelles for GSH-triggered delivery of arsenic species to cancer cells. Biomaterials, 35, 7088-7100 (2014). |
| 228. |
Peng, H.; Hu, B.; Liu, Q.; Yang, Z.; Lu, X.; Huang, R.; Li, X.-F.; Zuidhof, M.J.; Le, X.C.
Liquid chromatography combined with atomic and molecular mass spectrometry for speciation of arsenic in chicken liver. Journal of Chromatography A, 1370, 40-49 (2014). |
| 227. |
Wu, M.; Qian, Y.; Boyd, J.M.; Le, X.C; Hrudey, S.E.; Li, X.-F.
Direct large volume injection ultra-high performance liquid chromatography-tandem mass spectrometry determination of artificial sweeteners sucralose and acesulfame in well water. Journal of Chromatography A, 1359, 156-161 (2014). |
| 226. |
Dodmane, P. R.; Arnold, L.L.; Muirhead, D.E.; Suzuki, S, Yokohira, M.; Pennington, K.L.; Davé, B.J.; Lu, X.; Le, X.C.; Cohen, S.M.
Characterization of intracellular inclusions in the urothelium of mice exposed to inorganic arsenic. Toxicological Sciences, 137, 36-46 (2014). Open Access |
| 225. |
Li, J.; Wang, W.; Zhang, H.; Le, X.C.; Li, X.-F.
Glutathione mediated detoxification of halobenzoquinone drinking water disinfection byproducts in T24 cells. Toxicological Sciences, 141, 335-343 (2014). Open Access |
| 224. |
Banerjee, M.; Carew, M.W.; Roggenbeck, B.A.; Naranmandura, H.; Le, X.C.; Leslie, E.M.
A novel pathway for arsenic elimination: human multidrug resistance protein 4 (MRP4/ABCC4) mediates cellular export of dimethylarsinic acid [DMA(V)] and the diglutathione conjugate of monomethylarsonous acid [MMA(III)]. Molecular Pharmacology, 86, 168-179 (2014). |
| 223. |
Anwar-Mohamed, A.; Elshenawy, O.H.; Soshilov, A.A.; Denison, M.S.; Le, X.C.; Lars-Oliver Klotz, L.O.; El-Kadi, A.O.S.
Methylated pentavalent arsenic metabolites are bifunctional inducers as they induce Cytochrome P450 1A1 (CYP1A1) and NAD(P)H: quinone oxidoreducatase (NQO1) through AhR and Nrf2 dependent mechanisms. Free Radical Biology and Medicine, 67, 171-187 (2014). |
| 222. |
Normandin, L.; Ayotte, P.; Levallois, P.; Ibanez, Y.; Courteau, M.; Kennedy, G.; Chen, L.; Le, X.C.; Bouchard, M.
Biomarkers of arsenic exposure and effects in a Canadian rural population exposed through groundwater consumption. Journal of Exposure Science and Environmental Epidemiology, 24, 127-134 (2014). |
| 221. |
Pourrezaei, P.; Alpatova, A.; Chelme-Ayala, P.; Perez-Estrada, L.A.; Jensen-Fontaine, M.; Le, X.C.; Gamal El-Din, M.
Impact of petroleum coke characteristics on the adsorption of the organic fractions from oil sands process-affected water. International Journal of Environmental Science and Technology, 11, 2037-2050 (2014). |
| 220. |
Deng, B.; Lin, Y.; Wang, C.; Li, F.; Wang, Z.; Zhang, H.; Li, X.-F.; Le, X.C.
Aptamer binding assays for proteins: The thrombin example-A review. Analytica Chimica Acta, 837, 1-15 (2014). Open Access |
| 219. |
Li, F.; Aeran, R.; Pone, E. J.; Kang D.-K.; Liu L.; Le X.C.; Zhao W.
Probe and control of cell-cell interactions using bioengineered tools. In Karp, J.M.; Zhao, W. (Eds.) Miro- and Nanoengineering of the Cell Surface. Elsevier. Chapter 15, 349-370 (2014). ISBN: 978-1-4557-3146-6. |
| 218. |
Ali, M.M.; Li, F.; Zhang, Z.Q.; Zhang, K.X.; Kang, D.-K.; Le, X.C.; Zhao, W.
Rolling circle amplification: A versatile tool for chemical biology, materials science and medicine. Chemical Society Reviews, 43, 3324-3341 (2014). |
2013 | |
| 217. |
Zhang, H.; Li, F.; Dever, B.; Li, X.-F.; Le, X.C.
DNA-mediated homogeneous binding assays for nucleic acids and proteins. Chemical Reviews, 113(4), 2812-2841 (2013). |
| 216. |
Zhang, H.; Li, F.; Dever, B.; Wang, C.; Li, X.-F.; Le, X.C.
Assembling DNA through affinity binding to achieve ultrasensitive protein detection. Angewante Chemie International Edition, 52, 10698-10705 (2013). Open Access |
| 215. |
Li, F.; Zhang, H.; Wang, Z.; Li, X.; Li, X.-F.; Le, X. C.
Dynamic DNA assemblies mediated by binding-induced DNA strand displacement. Journal of the American Chemical Society, 135, 2443-2446 (2013). Open Access |
| 214. |
Li, F.; Lin, Y.; Le, X.C.
Binding-induced formation of DNA three-way junction and its application to protein detection and DNA strand displacement. Analytical Chemistry, 85(22), 10835-10841 (2013). |
| 213. |
Li, F.; Zhang, H.; Dever, B.; Li, X.-F.; Le, X. C.
Thermal stability of DNA functionalized gold nanoparticles. Bioconjugate Chemistry, 24(11), 1790-1797 (2013). Open Access |
| 212. |
Zhang, H.; Li, F.; Li, X.-F.; Le, X.C.
Yoctomole detection of proteins using solid phase binding-induced DNA assembly. Methods, 64(3), 322-330 (2013). Open Access |
| 211. |
Wu, M.; Zhang, H.; Wang, Z.; Shen, S.; Le, X.C.; Li, X.-F.
"One-pot'' fabrication of clickable monoliths for enzyme reactors. Chemical Communications, 49, 1407-1409 (2013). |
| 210. |
Le, X.C.; Hamula, C.L.A.; Li, X.F.
Selection of aptamers against S. pyogenes. United States Patent No. US8,507,203 B2, Issued on August 13, 2013. |
| 209. |
Calderon, R.L.; Hudgens, E.E.; Carty, C.; He, B.; Le, X.C.; Rogers, J.; Thomas, D.J.
Biological and behavioral factors modify biomarkers of arsenic exposure in a U.S. population. Environmental Research, 126, 134-144 (2013). Open Access |
| 208. |
Chen, B.; Lu, X.; Shen, S.; Arnold, L.L.; Cohen, S.M.; Le, X.C.
Arsenic speciation in the blood of arsenite-treated F344 rats. Chemical Research in Toxicology, 26(6), 952-962 (2013). |
| 207. |
Chen, B.; Cao, F.; Yuan, C.; Lu, X.; Shen, S.; Zhou, J.; Le, X.C.
Arsenic speciation in saliva of acute promyelocytic leukemia patients undergoing arsenic trioxide treatment. Analytical and Bioanalytical Chemistry, 405, 1903-1911 (2013). Open Access |
| 206. |
Naranmandura, H.; Rehman, K.; Le, X.C.; Thomas, D.J.
Formation of methylated oxyarsenicals and thioarsenicals in wild-type and arsenic (+3 oxidation state) methyltransferase knockout mice exposed to arsenate. Analytical and Bioanalytical Chemistry, 405, 1885-1891 (2013). |
| 205. |
Shen, S.; Wang, C.; Weinfeld, M.; Le, X.C.
Inhibition of nucleotide excision repair by arsenic. Chinese Science Bulletin, 58, 214-221 (2013). Open Access |
| 204. |
Xu, S.; Zhang, Y.F.; Carew, M.W.; Hao, W.H.; Loo, J.F.C.; Naranmandura, H.; Le, X.C.
Multidrug resistance protein 1 (ABCC1) confer resistance to arsenic compounds in human myeloid leukemic HL-60 cells. Archives of Toxicology, 87, 1013-1023 (2013). |
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Shen, S.; Li, X.-F.; Cullen, W.R.; Weinfeld, M.; Le, X.C.
Arsenic binding to proteins. Chemical Reviews, 113(10), 7769-7792 (2013). Open Access |
2012 | |
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A molecular translator that acts by binding-induced strand displacement for a homogenous protein assay. Angewandte Chemie International Edition, 51, 9317-9320 (2012). |
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Mesoporous materials in peptidome analysis. Angewandte Chemie International Edition, 51, 3518-3519 (2012) |
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Binding-induced DNA assembly and its application to yoctomole detection of proteins. Analytical Chemistry, 84, 877-884 (2012). |
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Binding-induced fluorescence turn-on assay using aptamer-functionalized silver nanocluster DNA probes. Analytical Chemistry, 84, 5170-5174 (2012). |
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Liu, Y.; Wang, C.; Li, F.; Shen, S.; Tyrrell, D.L.J.; Le, X.C.; Li, X-F.
DNase-mediated single-cycle selection of aptamers for proteins blotted on a membrane. Analytical Chemistry, 84, 7603-7606 (2012). |
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Applications of Aptamer Affinity Chromatography. Trends in Analytical Chemistry, 41, 46-57 (2012). |
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Wlodarczyk, B., Spiegelstein, O.; Hill, D.; Le, X.C.; Finnell, R.H.
Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate. Toxicology Letters, 215(3), 214-218 (2012). |
| 195. |
Suzuki, S,; Arnold, L.L.; Pennington, K.L.; Kakiuchi-Kiyota, S.; Chen, B.; Lu, X.; Le, X.; Cohen, S.M.
Effects of co-administration of dietary sodium arsenate and 2,3-dimercaptopropane-1-sulfonic acid (DMPS) on the rat bladder epithelium. Toxicology, 299, 155-159 (2012). |
| 194. |
Qi, H.Y.; Chen, B.W.; Le, X.C.; Rong, J.H.
Concomitant induction of heme oxygenase-1 attenuates the cytotoxicity of arsenic species from Lumbricus extract in human liver HepG2 cells. Chemistry and Biodiversity, 9, 739-754 (2012). |
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Li, X.F.; Liu, Y.; Le, X.C.
Apparatus and method for single cycle selection of aptamers. U.S. patent application No. 61/693,878, filed on August 28, 2012. |
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Binding-induced hairpin detection system. US patent application. Publication No. US 2012/0156678A1. Pub. Date: June 21, 2012. |
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Arsenic-protein binding: a quantitative overview. In Ng, J.C.; Noller, B.N.; Naidu, R.; Bundschuh J.; and Bhattacharya P. (Eds.) Understanding the Geological and Medical Interface of Arsenic. Proceedings of the International Arsenic Congress. Australia. July 22-29, 2012. CRC Press, Taylor & Francis Group, London, UK. pp 189-192. 2012. |
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Affinity capillary electrophoresis in the study of DNA damage, repair, and methylation. In Pawliszyn, J.; Le, X. C.; Li, X-F.; Lee, H. K. (Eds); Comprehensive Sampling and Sample Preparation. Elsevier, Academic Press: Oxford, UK. (ISBN: 9780123813732). Volume 3. Chapter 3.11, pp 231-260 (2012). |
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Enzyme digestion for speciation of arsenic. In Pawliszyn, J.; Le, X. C.; Li, X-F.; Lee, H. K. (Eds); Comprehensive Sampling and Sample Preparation. Elsevier, Academic Press: Oxford, UK. (ISBN: 9780123813732). Volume 3. Chapter 3.21, pp 421-434 (2012). |
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2011 | |
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Competitive protection of aptamer-functionalized gold nanoparticles by controlling the DNA assembly. Analytical Chemistry, 83, 6464-6467 (2011). |
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Aptamer capturing of enzymes on magnetic beads to enhance assay specificity and sensitivity. Analytical Chemistry, 83, 6464-6467 (2011). |
| 185. |
Hamula, C.L.A.; Le, X.C; Li, X.-F.
DNA aptamers binding to multiple prevalent M-types of Streptococcus pyogenes. Analytical Chemistry, 83, 3640-3647 (2011). |
| 184. |
Hamula, C.L.A.; Zhang, H.; Li, F.; Wang, Z.; Le, X.C.; Li, X.-F.
Selection and analytical applications of aptamers binding microbial pathogens. Trends in Analytical Chemistry, 30, 1587-1597 (2011). |
| 183. |
Naranmandura, H.; Carew, M.; Xu, S.; Leslie, E.; Lee, J.; Weinfeld, M.; Le, X.C.
Comparative toxicity of arsenic metabolites in human bladder cancer EJ-1 cells. Chemical Research in Toxicology, 24, 1586-1596 (2011). |
| 182. |
Chen, B.; Arnold, L.L.; Cohen, S.M.; Thomas, D.J.; Le, X.C.
Mouse arsenic (+3 oxidation state) methyltransferase genotype affects metabolism and tissue dosimetry of arsenicals after arsenite administration in drinking water. Toxicological Sciences, 124(2), 320-326 (2011). |
| 181. |
Carew, M.W.; Naranmandura, H.; Shukalek, C.B.; Le, X.C.; Leslie, E.M.
Monomethylarsenic diglutathione [MMAIII(GS)2] transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Drug Metabolism and Disposition, 39(12), 2298-2304 (2011). |
| 180. |
Wei, L.; Liu, J.; Le, X.C.; Han, Y.; Tong, Y.; Lau, A.S.Y.; Rong, J.
Pharmacological induction of leukotriene B4-12-hydroxydehydrogenase suppresses the oncogenic transformation of human hepatoma HepG2 cells. International Journal of Oncology, 39, 735-745 (2011). DOI: 10.3892/ijo.2011.1082 |
| 179. |
McKnight-Whitford, A.; Le, X.C.
Electrospray Mass Spectrometry for Arsenic Speciation Analysis. Encyclopedia of Analytical Chemistry, eds R.A. Meyers, John Wiley: Chichester. Published December 15, 2011. DOI: 9780470027318.a9234 |
2010 | |
| 178. |
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Detection of E. coli O157: H7 using gold nanoparticle labelling and inductively coupled plasma-mass spectrometry. Analytical Chemistry, 82, 3399-3403 (2010). |
| 177. |
Lew, K.; Acker, J.A.; Gabos, S.; Le, X.C.
Biomonitoring of arsenic in urine and saliva of children playing on playgrounds constructed from chromated copper arsenate-treated wood. Environmental Science and Technology, 44, 3986-3991 (2010). |
| 176. |
McKnight-Whitford, A.; Chen, B.; Naranmandura, H.; Zhu, C.; Le, X.C.
New method and detection of high concentrations of monomethylarsonous acid detected in contaminated groundwater. Environmental Science and Technology, 44, 5875-5880 (2010). |
| 175. | Anichina, J.; Zhao, Y.; Hrudey, S.E.; Le, X.C.; Li, X.F.
Electrospray ionization mass spectrometry characterization of interactions of newly identified water disinfection byproducts halobenzoquinones with oligodeoxynucleotides. Environmental Science and Technology, 44, 9557-9563 (2010). |
| 174. |
Suzuki, S.; Arnold, L.A.; Pennington, K.L.; Chen, B.; Naranmandura, H.; Le, X.C.; Cohen, S.M.
Dietary administration of sodium arsenite to rats: Relations between dose and urinary concentrations of methylated and thio-metabolites and effects on the rat urinary bladder epithelium. Toxicology and Applied Pharmacology, 244, 99-105 (2010). |
| 173. |
Liu, F.; Le, X.C.; McKnight-Whitford, A.; Xia, Y.; Wu, F.; Elswick, E.; Johnson, C.C.; Zhu, C.
Antimony speciation and contamination of waters in the Xikuangshan antimony mining and smelting area, China. Environmental Geochemistry and Health, 32, 401-413 (2010). |
| 172. |
Lu, M.; Li, X.-F.; Le, X.C.; Weinfeld, M.; Wang, H.
Identification and characterization of cysteinyl exposure in proteins by selective mercury labelling and nano-electrospray ionization quadrupole time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry, 24, 1523-1532 (2010). |
| 171. |
Chen, L.W.; Lu, X.; Le, X.C.
Complementary chromatography separation combined with hydride generation - inductively coupled plasma mass spectrometry for arsenic speciation in human urine. Analytica Chimica Acta, 675, 71-75 (2010). |
| 170. |
Wagner, M.K.; Li, F.; Li, J.; Li, X.-F.; Le, X.C.
Quantum dot based assays for cancer biomarkers. Analytical and Bioanalytical Chemistry, 397, 3213-3224 (2010). |
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Zhao, Q.; Le, X.C.
Most recent advances in chromatography. Chinese Journal of Chromatography, 28, 431-433 (2010). |
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McGuigan, C.F.; Hamula, C.L.A. ; Huang, S.; Gabos, S.; Le, X.C.
A review on arsenic concentrations in Canadian drinking water. Environmental Reviews, 18, 291-307 (2010). |
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Detection of binding factors with fluorescence polarization. US patent: 10/763,259. September 28, 2010. |
| 166. |
Murphy, T.; Sampson, M.; Le, X.C.; Irvine, K.; Gerads, R.; Smith, L.; Parr, T.
Arsenic bioaccumulation in an arsenic rich area of Cambodia. In K. Irvine, T. Murphy, V. Vanchan, S. Vermette (Eds). Water Resources and Development in Southeast Asia. Pearson Learning Solutions: Boston. 57-88 (2010). |
2009 | |
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Wang, H.; Lu, M.; Tang, M.-S.; Van Houten, B.; Ross, J.B.A; Weinfeld, M.; Le, X.C.
DNA Wrapping is required for DNA damage recognition in the E. coli DNA nucleotide excision repair pathway. Proceedings of the National Academy of Sciences USA, 106, 12849-12854 (2009). |
| 164. |
Qin, J.; Lehr, C.R.; Yuan, C.; Le, X.C.; McDermott, T.R.; Rosen, B.P.
Biotransformation of arsenic by a Yellowstone thermoacidophilic eukaryotic alga. Proceedings of the National Academy of Sciences USA, 106, 5213-5217 (2009). |
| 163. |
Yan, H.; Wang, N.; Weinfeld, M.; Cullen, W.R.; Le, X.C.
Identification of arsenic-binding proteins in human cells by affinity chromatography and mass spectrometry. Analytical Chemistry, 81, 4144-4152 (2009). |
| 162. |
Zhao, Q.; Lu, X.; Yuan, C.; Li, X.-F.; Le, X.C.
Aptamer-linked assay for thrombin using gold nanoparticle amplification and inductively coupled plasma mass spectrometry detection. Analytical Chemistry, 81, 7484-7489 (2009). |
| 161. |
Zhang, H.; Li, X.-F.; Le, X.C.
Differentiation and detection of PDGF isomers and their receptors by tunable aptamer capillary electrophoresis. Analytical Chemistry, 81, 7795-7800 (2009). |
| 160. |
Wang, Z.; Lu, M.; Wang, X.; Yin, R.; Song, Y.; Le, X.C. Wang, H.
Quantum dots enhanced ultrasensitive detection of DNA adducts. Analytical Chemistry, 81, 10285-10289 (2009) |
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Arsenite and its mono- and di-methylated trivalent metabolites enhance the formation of BPDE-DNA adducts in Xeroderma pigmentosum complementation group A cells. Chemical Research in Toxicology, 22, 382-390 (2009). |
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Drobna, Z.; Narenmandura, H.; Kubachka, K.M.; Edwards, B.C.; Herbin-Davis, K.; Styblo, M.; Le, X.C.; Creed, J.T.; Maeda, N.; Hughes, M.F.; Thomas, D.J.
Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate. Chemical Research in Toxicology, 22, 1713-1720 (2009). Cover feature. |
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Wang, C.; Feng, F.; Wang, Z.; Li, T.; Le, X.C.; Wang, H.
Synthesis and characterization of long DNA probes containing a single stereomer of anti-BPDE-N2-dG. Chemical Research in Toxicology, 22, 676-682 (2009). |
| 156. |
Naranmandura, H.; Ogra, Y.; Iwata, K.; Lee, J.; Suzuki, K.T.; Weinfeld, M.; Le, X.C.
Evidence for toxicity differences between inorganic arsenite and thioarsenicals in human bladder cancer. Toxicology and Applied Pharmacology, 238, 133-140 (2009). |
| 155. |
Naranmandura, H.; Suzuki, N.; Takano, J.; McKnight-Whitford, T.; Ogra, Y.; Suzuki, K.T.; Le, X.C.
Systemic distribution and speciation of diphenylarsinic acid fed to rats. Toxicology and Applied Pharmacology, 237, 214-220 (2009). |
| 154. |
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Differential cytotoxic effects of arsenic compounds in human acute promyelocytic leukemia cells. Toxicology and Applied Pharmacology, 239, 64-70 (2009). |
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Suzuki, S.; Arnold, L.L.; Pennington, K.L.; Chen, B.; Le, X.C.; Cohen, S.M.
Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium. Toxicology Letters, 187, 124-129 (2009). |
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Enzymatic digestion and chromatographic analysis of arsenic species released from proteins. Journal of Chromatography A, 1216, 3985-3991 (2009). |
| 151. |
Goulko, A.A.; Feng Li, F.; Le, X.C.
Bioanalytical applications of aptamer and molecular beacon probes in fluorescence affinity assays. Trends in Analytical Chemistry, 28, 878-892 (2009). |
| 150. |
LeBlanc, A.; Shen, S.; Lew, K.; Weinfeld, M.; Le, X.C.
Detection of BPDE-DNA adducts in mononuclear white blood cells by capillary electrophoresis immunoassay and its application to studying the effect of glutathione depletion. Electrophoresis, 30, 1558-1563 (2009). |
| 149. |
Li, R.B.; Wu, R.A.; Wu, M.H.; Zou, H.F.; Ma, H.; Yang, L.; Le, X.C.
MEKC-LIF analysis of rhodamine123 delivered by carbon nanotubes in K562 cells. Electrophoresis, 30, 1906-1912 (2009). |
| 148. |
Zhao, Q.; Le, X.C.
Recent advances in aptamer affinity chromatography. Chinese Journal of Chromatography, 27(5), 556-565 (2009). |
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Liu, J.; Le, X.C.
Interaction of arsenic species with proteins. Journal of Analytical Science, 25(4), 465-472 (2009). |
| 146. |
Chen, B.; Narenmandula, H.; Lu, M.; Le, X.C.
Metabolism, toxicity, and biomonitoring of arsenic species. Progress in Chemistry, 21, 474-482 (2009). |
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Yuan, C.; Le, X.C.
Arsenic speciation analysis. Progress in Chemistry, 467-473 (2009). |
| 144. |
Wade, T.J.; Xia, Y.; Wu, K.; Li, Y.; Ning, Z.; Le, X.C.; Lu, X.; Feng, Y.; He, X.; Mumford, J.L.
Increased mortality associated with well-water arsenic exposure in Inner Mongolia, China. International Journal of Environmental Research and Public Health, 6(3), 1107-1123 (2009). |
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Xia, Y.; Wade, T.J.; Wu, K.; Li, Y.; Ning, Z.; Le, X.C.; He, X.; Chen, B.; Feng, Y.; Mumford, J.L.
Well water arsenic exposure, arsenic induced skin-lesions and self-reported morbidity in Inner Mongolia. International Journal of Environmental Research and Public Health, 6, 1010-1025 (2009). |
| 142. |
Lu, X.; Nguyen, N.; Gabos, S.; Le, X.C.
Arsenic speciation in cattail (Typha latifolia) using chromatography and mass spectrometry. Molecular Nutrition and Food Research, 53, 566-571 (2009). |
| 141. |
Guthrie, J.W.; Shao, Y.; Le, X.C.
Aptamers in affinity separations: Capillary electrophoresis. In Y-F. Li and Y. Lu (Ed). Functional Nucleic Acids for Sensing and Other Analytical Applications. Chapter 7, 255-270 (2009). |
2008 | |
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Zhang, H.; Li, X.-F.; Le, X.C.
Tunable aptamer capillary electrophoresis and its application to protein analysis. Journal of American Chemical Society, 130, 34-35 (2008). |
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Hamula, C.L.A.; Zhang, H.; Guan, L.L.; Li, X.-F.; Le, X.C.
Selection of aptamers against live bacterial cells. Analytical Chemistry, 80, 7812-7819 (2008). |
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Zhao, Q.; Li, X.-F.; Shao, Y.; Le, X.C.
Aptamer-based affinity chromatographic assays for thrombin. Analytical Chemistry, 80, 7586-7593 (2008). |
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Zhao, Q.; Li, X.-F.; Le, X.C.
Aptamer-modified monolithic capillary chromatography for protein separation and detection. Analytical Chemistry, 80, 3915-3920 (2008). |
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Shen, L.; Chen, Z.; Li, Y.; He, S.; Xie, S.; Xu, X.; Liang, Z.; Meng, X.; Li, Q.; Zhu, Z.; Li, M.; Le, X.C.; Shao, Y.
Electrochemical DNAzyme sensor for lead based on amplification of DNA-Au bio-bar codes. Analytical Chemistry, 80, 6323-6328 (2008). |
| 135. |
Lu, M.; Wang, H.; Li, X.-F.; Le, X.C.
Identification of reactive cysteines in a protein using arsenic labeling and collision-induced dissociation tandem mass spectrometry. Journal of Proteome Research, 7, 3080-3090 (2008). |
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Yuan, C.; Lu, X.; Qin, J.; Rosen, B.P.; Le, X.C.
Volatile Arsenic Species Released from Escherichia coli Expressing the AsIII S-adenosylmethionine Methyltransferase Gene. Environmental Science and Technology, 42, 3201-3206 (2008). |
| 133. |
Yuan, C.; Lu, X.; Orr, N.; Wang, Z.; Xia, Y.; Wade, T.; Mumford, J.; Le, X.C.
Arsenic speciation analysis in human saliva. Clinical Chemistry, 54, 163-171 (2008). |
| 132. |
Shen, S.; Lee, J.; Weinfeld, M.; Le, X.C.
Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis. Molecular Carcinogenesis, 47, 508-518 (2008). |
| 131. |
Lew, K.; Yuan, C.; Acker, J.A.; Le, X.C.
Salivary arsenic as a biomarker for arsenic exposure. Cell Biology and Toxicology, 24, 367-371 (2008). |
| 130. |
Nascimento, M.G.; Suzuki, S.; Wei, M.; Tiwari, A.; Arnold, L.L.; Lu, X.; Le, X.C.; Cohen, S.M.
Cytotoxicity of combinations of arsenicals on rat urinary bladder urothelial cells in vitro. Toxicology, 249, 69-74 (2008). |
| 129. |
Goulko, A.A.; Zhao, Q.; Guthrie, J.W.; Zou, H., Le, X.C.
Fluorescence Polarization: Recent Bioanalytical Applications, Pitfalls, and Future Trends. In U. Resch-Genger (Ed). Methods and Applications of Fluorescence. Springer Series Fluorescence, 5, 303-322 (2008). |
2007 | |
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Zhang, H.; Zhao, Q.; Li, X.-F.; Le, X.C.
Ultrasensitive assays for proteins Analyst, 132, 724-737 (2007). |
| 127. |
Lu, M.; Wang, H.; Li, X.-F.; Arnold, L.L; Cohen, S.M.; Le, X.C.
Binding of dimethylarsinous acid to cysteine 13 in the alpha chain of rat hemoglobin is responsible for retention of arsenic in rat blood. Chemical Research in Toxicology, 20, 27-37 (2007). |
| 126. |
Wang, Z.; Zhang, H.; Li, X.F.; Le, X.C.
Study of interactions between arsenicals and thioredoxins (human and E. coli) using mass spectrometry. Rapid Communication in Mass Spectrometry, 21, 3658-3666 (2007). |
| 125. |
Cohen, S.M.; Ohnishi, T.; Arnold, L.L.; Le, X.C.
Arsenic-induced bladder cancer in an animal model. Toxicology and Applied Pharmacology, 222, 258-263 (2007). |
| 124. |
Li, X.S.; Glasauer, S.; Le, X.C.
Speciation of vanadium in oilsand coke and bacterial culture by high performance liquid chromatography inductively coupled plasma mass spectrometry. Analytica Chimica Acta, 602, 17-22 (2007). |
| 123. |
Muangnoi, P.; Lee, J.; Thepouyporn, A.; Lu, M.; Le, X.C.; Weinfeld, M.; Changbumrung, S.
Cytotoxicity, apoptosis and DNA damage induced by Alpinia galanga rhizome extract. Planta Medica, 73, 748-54 (2007). |
| 122. |
Zhao, Q.; Le, X.C.
Environmental analysis of single cells. Analytical and Bioanalytical Chemistry, 387, 45-49 (2007). |
| 121. |
Xiao, H.; Yang, L.; Zou, H.; Yang, L.; Le, X.C.
Analysis of oxidized multi-walled carbon nanotubes in single K562 cells by capillary electrophoresis with laser-induced fluorescence. Analytical and Bioanalytical Chemistry, 387, 119-126 (2007). |
| 120. |
Guthrie, J.W.; Ryu, J.H.; Le, X.C.; WiebeLe, L.I.
Characterization of a cyclodextrin-oligonucleotide complex by capillary electrophoresis using laser-induced fluorescence. Journal of Pharmacy and Pharmaceutical Sciences, 10(2), 244-253 (2007). |
| 119. |
Zhang, H.; Zhao, Q.; Le, X.C.
Ultrasensitive protein detection- the use of aptamers as probes. Bioforum Europe, 11(1/2), 54-56 (2007). |
2006 | |
| 118. |
Shen, S.; Lee, J.; Sun, X.; Wang, H.; Weinfeld, M.; Le, X.C.
Elevation of cellular BPDE uptake by human cells: a possible factor contributing to co-carcinogenicity by arsenite. Environmental Health Perspectives, 114, 1832-1837 (2006). |
| 117. |
Zhang, H.; Wang, Z.; Li, X.F.; Le, X.C.
Ultrasensitive detection of proteins by amplification of affinity aptamers. Angewandte Chemie International Edition, 45, 1576-1580 (2006). A Press Release about this work is available. |
| 116. |
Hamula, C.A.; Wang, Z.; Zhang, H.; Kwon, E.; Gabos, S.; Li, X.F.; Le, X.C.
Chromium on the hands of children after playing in playgrounds built from chromated copper arsenate (CCA)-treated wood. Environmental Health Perspectives, 114, 460-465 (2006). |
| 115. |
Hamula, C.L.A.; Guthrie, J.W.; Zhang, H.; Li, X.-F.; Le, X.C.
Selection and analytical applications of aptamers. Trends in Analytical Chemistry, 25, 681-691 (2006). |
| 114. |
Fu, H.; Guthrie, J.; Le, X.C.
Study of binding stoichiometries of the human immunodeficiency virus type 1 reverse transcriptase by capillary electrophoresis and laser induced fluorescence polarization using aptamers as probes. Electrophoresis, 27, 433-441 (2006). |
| 113. |
Xiao, H.; Li, X.; Zou, H.; Yang, L.; Wang, Y.; Wang, H.; Le, X.C.
CE-LIF coupled with flow cytometry for high-throughput quantitation of fluorophores in single intake cells. Electrophoresis, 27, 3452-3459 (2006). |
| 112. |
Guthrie, J.W.; Hamula, C.L.A.; Zhang, H.; Le, X.C.
Assays for cytokines using aptamers. Methods, 38, 324-330 (2006). |
| 111. |
Mo J., Y. Xia, Y.; Wade, T.J.; Schmitt, M.; Le, X.C.; Dang, R.; Mumford, J.L.
Chronic Arsenic Exposure and Oxidative Stress: OGG1 Expression and Arsenic Exposure, Nail Selenium, and Skin Hyperkeratosis in Inner Mongolia. Environmental Health Perspectives, 114, 835-841 (2006). |
| 110. | Li, Y.; Xia, Y.; He, L.; Ning, Z.; Wu, K.; Zhao, B.; Le, X.C..; Kwok, R.; Schmitt, M.; Wade, T.; Mumford, J.; Otto, D.
Neurosensory effects of chronic exposure to arsenic via drinking water in Inner Mongolia: Signs, symptoms and pinprick testing." Journal of Water Health, 4, 29-37 (2006). |
| 109. |
Xiao, H.; Li, X.; Zou, H.; Yang, L.; Yang, Y.; Wang, Y.; Wang, H.; Le, X.C.
Immunoassay of P-glycoprotein on single cell by capillary electrophoresis with laser induced fluorescence detection. Analytica Chimica Acta, 556, 340-346 (2006). |
| 108. |
Gong, Z.; Lu, X.; Watt, C.; Wen, B.; He, B.; Mumford, J.; Ning, Z.; Xia, Y.; Le, X.C.
Speciation analysis of arsenic in groundwater from Inner Mongolia with an emphasis on acid-leachable particulate arsenic. Analytical Chimica Acta, 555, 181-187 (2006). |
2005 | |
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Wang, H.; Lu, M.; Le, X.C.
DNA-Driven focusing for protein-DNA binding assays using capillary electrophoresis. Analytical Chemistry, 77, 4985-4990 (2005). |
| 106. |
Le, X.C.; Pavski, V.; Wang, H.
Affinity recognition, capillary electrophoresis and laser induced fluorescence polarization for ultrasensitive bioanalysis. Canadian Journal of Chemistry, 83, 185-194 (2005). |
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Schmitt, M.T.; Schreinemachers, D.; Wu, K.; Ning, Z.; Zhao, B.; Le, X.C.; Mumford, J.L.
Nails as a biomarker of arsenic exposure from well water in an Inner Mongolian population: Comparing atomic fluorescence spectrometry and neutron activation analysis. Biomarkers, 10, 95-104 (2005). |
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Spiegelstein, O.; Gould, A.; Wlodarczyk, B.; Tsie, M.; Lu, X.; Le, X.C.;
Troen, A.; Selhub, J.; Piedrahita, J.A.; Salbaum, J.M.; Kappen, C.; Melnyk, S.; James, S.J.; Finnell, R.H
Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicology and Applied Pharmacology, 203, 18-26 (2005). |
| 103. | Spiegelstein, O.; Lu, X.; Le, X.C.;
Troen, A.; Selhub, J.; Melnyk, S.; James, S.J.; Finnell, R.H.
Effects of dietary folate intake and folate binding protein-2 (FOLBP2) on urinary speciation of sodium arsenate in mice. Environmental Toxicology and Pharmacology, 19, 1-7 (2005). |
| 102. | Watt, C; Le, X.C.
Arsenic compounds in water. In Water Quality and Resource Development; Lehr, J.H., Keeley, J., Lehr, J., Eds; Water Encyclopedia; Wiley: Hoboken, NJ. 5, 7-14 (2005). |
2004 | |
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Lu, M.; Wang, H.; Li, X.-F.; Lu, X.; Cullen, W.R.; Arnold, L.L; Cohen, S.M.; Le, X.C.
Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood. Chemical Research in Toxicology, 17, 1733-1742 (2004). |
| 100. |
Paproski, R.; Le, X.C.
Boric acid assisted ion exchange chromatography for separating arsenic species. Analytical Chimica Acta, 526, 69-76 (2004). |
| 99. |
Kwon, E.; Zhang, H.; Wang, Z.; Jhangri, G.S.; Fok, N.; Gabos, S.; Li, X.F.; Le, X.C.
Arsenic on the hands of children after playing in playgrounds. Environmental Health Perspectives, 112, 1375-1380 (2004). |
| 98. | Gong, Z.; Teixeira, C.; Xing, J.;
Yokota, J.; Kohno, T.; Gabos, S.; Le, X.C.; Li, X.F.
Electronic microarray technique for detection of nine base substitutions including single nucleotide polymorphisms in the human OGG1 gene. Clinical Chemistry, 50, 1441-1444 (2004). |
| 97. | Wang, Z.; Zhou, J.; Lu, X.; Gong, Z.; Le, X.C.
Arsenic speciation in urine from acute promyelocytic leukemia patients undergoing arsenic trioxide treatment. Chemical Research in Toxicology, 17, 95-103 (2004). |
| 96. | Le, X.C.; Lu, X.; Li, X.-F.
Arsenic speciation. Analytical Chemistry, 76, 26A-33A (2004). |
| 95. | Le, X.C.; Weinfeld, M.
Cellular Responses to Arsenic: DNA Damage and Defense Mechanisms. Awwa Research Foundation: Denver, CO. pp.1-147 (2004). |
2003 | |
| 94. | Lu, X.; Arnold, L.L.; Cohen, S.M.;
Cullen,W.R.; Le, X.C.
Speciation of dimethylarsinous acid and trimethylarsine oxide in urine from rats fed with dimethylarsinic acid and dimercaptopropane sulfonate. Analytical Chemistry, 75, 6463-6468 (2003). |
| 93. | Mei, N.; Lee, J.; Sun, X.; Xing,
J.Z.; Hanson, J.; Le, X.C.; Weinfeld, M.
Genetic predisposition to the cytotoxicity of arsenic: the role of DNA damage and ATM. FASEB Journal, 17, 2310-2312 (2003). |
| 92. | Jiang, G.; Gong, Z; Li, X-F.; Cullen, W.R.; Le, X.C.
Interaction of trivalent arsenicals with metallothionein. Chemical Research in Toxicology, 16, 873-880 (2003). |
| 91. | Wang, H.; Lu, M.; Mei, N.; Lee, J.; Weinfeld, M.; Le, X.C.
Immunoassays using capillary electrophoresis laser induced fluorescence detection for DNA adducts. Analytica Chimica Acta, 500, 13-20 (2003). |
| 90. | Lammon, C.A.; Le, X.C.; Hood, R.D.
Pretreatement with periodate-oxidized adenosine enhances the developmental toxicity of inorganic arsenic in mice. Birth Defects Research, Part B, Developmental and Reproductive Toxicology. 68, 335-343 (2003). |
| 89. | Pavski, V.; Le, X.C.
Ultrasensitive protein-DNA binding assays. Current Opinions in Biotechnology, 14, 65-73 (2003). |
| 88. | Wang, H.; Lu, M.; Weinfeld, M.; Le, X.C.
Enhancement of immunocomplex detection and application to assays for DNA adduct of benzo[a]pyrene. Analytical Chemistry, 75, 247-254 (2003). |
| 87. | Spiegelstein, O.; Lu, X.; Le,
X.C.; Troen, A.; Selhub, J.; Melnyk, S.; James, J.S.; Finnell, R.H.
Effect of dietary folate intake and folate binding protin-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicology Letters, 145, 167-174 (2003). |
| 86. | Jing, B.; Lu, X.; Le, X.C.; Yu, B.
Speciation analysis of arsenic in food samples with high performance liquid chromatography inductively coupled plasma mass spectrometry. Chinese Journal of Chromatography, 21, 545-548 (2003). |
| 85. | Jiang, G.; Lu, X.; Gong, Z.; Cullen,
W.R.; Le, X.C.
Trivalent arsenic species: analysis, stability, and interaction with a protein. In W.R. Chappell, C.O. Abernathy, R.L. Calderon and D.J. Thomas (Eds.), Arsenic Exposure and Health Effects, Elsevier, New York. 51-68 (2003). |
| 84. | Cohen, S.M.; Le, X.C.; Lu, X.; Cano, M.; Arnold, L.L.
Carcinogenicity of Dimethylarsinic Acid [DMA(V)]. In W.R. Chappell, C.O. Abernathy, R.L. Calderon and D.J. Thomas (Eds.), Arsenic Exposure and Health Effects, Elsevier, New York. 321-335 (2003). |
| 83. | Spiegelstein, O.; Lu, X.; Le, X.C.;
Finnell, R.H.
Urinary Speciation of Sodium Arsenate in Folate Receptor Knockout Mice. In W.R. Chappell, C.O. Abernathy, R.L. Calderon and D.J. Thomas (Eds.), Arsenic Exposure and Health Effects, Elsevier, New York. 337-344 (2003). |
2002 | |
| 82. | Lam, M.; Le, X.C.
Competitive immunoassay for vancomycin using capillary electrophoresis with laser-induced fluorescence detection. Analyst, 127, 1633-1637 (2002). |
| 81. | Wang, H.; Xing, J.; Tan, W.; Lam, M.; Carnelley, T.; Weinfeld, M.; Le, X.C.
Binding stoichiometry of DNA adducts with antibody studied by capillary electrophoresis and laser-induced fluorescence. Analytical Chemistry, 74, 3714-3719 (2002). |
| 80. | Gong, Z.; Jiang, G.; Cullen, W.R.; Aposhian, H.V.; Le, X.C.
Determination of arsenic metabolic complex excreted in human urine after administration of sodium 2,3-dimercapto-1-propane sulfonate. Chemical Research in Toxicology, 15, 1318-1323 (2002). |
| 79. | Cohen, S.M.; Arnold, L.L.; Uzvolgyi, E.; Cano, M.; St. John, M.; Yamamoto, S.; Lu, X.; Le, X.C.
Possible role of dimethylarsinous acid on dimethylarsinic acid-induced urothelial toxicity and regeneration in the rat. Chemical Research in Toxicology, 15, 1150-1157 (2002). |
| 78. | Takao, M.;, Kanno, S,; Shiromoto, T.; Hasegawa, R.; Ide, H.; Ikeda, S.; Sarker, A.H.; Seki, S.; Xing, J.Z.; Le, X.C.; Weinfeld, M.; Kobayashi, K.; Miyazaki, J.; Muijtjens, M.; Hoeijmakers, J.H.J.; van der Horst, G.; Yasui, A.
Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homologue for repair of thymine glycols. EMBO Journal, 21, 3486-3493 (2002). |
| 77. |
Le, X.C.; Wan, Q.H.; Lam, M.T.
Fluorescence polarization detection for affinity capillary electrophoresis. Electrophoresis, 23, 903-908 (2002). |
| 76. |
Gong, Z.; Lu, X.; Ma, M.; Watt, C.; Le, X.C.
Arsenic speciation analysis. Talanta, 58, 77-96 (2002). |
| 75. |
Lam, M.T.; Boulet, C.A.; Le, X.C.
Development of a tetramethylrhodamine-labeled probe for capillary electrophoresis-based competitive immunoassay of staphylococal enterotoxin B. Analytica Chimica Acta, 457, 21-28 (2002). |
| 74. | Xing, J.Z.; Lee, J.; Leadon, S.A.; Le,X.C.; Weinfeld, M.
Immunofluorescence detection of radiation-induced DNA base damage. Military Medicine, 167 (Suppl. 1), 2-4 (2002). |
| 73. | Karagas, M.R., Nelson, H.H.;
Kelsey, K.T.; Morris, S.; Blum, J.; Tosteson, T.D.; Carey, M.; Lu, X.; Le, X.C.
Urinary arsenic species in relation to drinking water, toenail arsenic concentrations and genetic polymorphisms in GSTM1 in New Hampshire. Progress in Nucleic Acid Research, Chapter 17, 251-261 (2002). |
| 72. | Watt, C.; Le, X.C.
Arsenic speciation in natural waters. In Cai, Y. (Ed). Biogeochemistry of Trace Elements. American Chemical Society Symposium Series, ACS, Washington, DC. 11-32 (2002). |
2001 | |
| 71. | Pavski, V.; Le, X.C.
Detection of human immunodeficiency virus type 1 reverse transcriptase using aptamers as probes in affinity capillary electrophoresis. Analytical Chemistry, 73, 6070-6076 (2001). |
| 70. | Gong, Z.; Lu, X.; Cullen, W.R.;
Le, X.C.
Unstable trivalent arsenic metabolites, monomethylarsonous acid and dimethylarsinous acid. Journal of Analytical Atomic Spectrometry, 16, 1409-1413 (2001). |
| 69. | Carnelley, T.J.; Barker, S.; Tan,
W.G.; Weinfeld, M.; Le, X.C.
Synthesis, characterization, and applications of a fluorescent DNA damage probe. Chemical Research in Toxicology, 14, 1513-1522 (2001). |
| 68. | Wlodarczyk, B.; Spiegelstein, O.;
Waes, J.G.; Vorce, R.L.; Lu, X.; Le, X.C.; Finnell, R.H.
Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 (Folbp2) knockout mice. Toxicology & Applied Pharmacology, 177, 238-246 (2001). |
| 67. | Tian, D.; Ma, H.; Feng, Z.; Xia,
Y.; Le, X.C.; Ni, Z.; Allen, J.; Collins, B.; Mumford, J.L.
Micronuclei analysis in human exfoliated epithelia from the residents chronically exposed to arsenic via drinking water in Inner Mongolia, China. Journal of Toxicololgy and Environmental Health Part A, 64, 473-84 (2001). |
| 66. |
Karagas, M.R.; Le, X.C.; Morris, S.; Blum, J.; Lu, X.; Spate, V.; Carey,
M.; Stannard, V.; Llaue, B.; Tosteson, T.D.
Markers of low level arsenic exposure for evaluating human cancer risks in a US population. Int. J. Occupat. Med. Environ. Health, 14, 171-175 (2001). |
| 65. |
Thomas, D.J.; Del Razo, L.M.; Schreinemachers, D.M.; Hudgens, E.D.; Le, X.C.; Calderon, R.L.
Dose-response relationships for the metabolism and urinary excretion of arsenicals in humans. In W.R. Chappell, C.O. Abernathy and R.L. Calderon (Eds.), Arsenic Exposure and Health Effects, Elsevier Science. pp. 353-366 (2001). |
| 64. | Aposhian, V.H.; Gurzau, E.S.; Le,
X.C.; Gurzau, A.; Zakharyan, R.A.; Cullen, W.R.; Healy, S.M.;
Gonzalez-Ramirez, D.; Morgan, D.L.; Sampayo-Reyes, A.; Wildfang, E.;
Radabaugh, T.R.; Petrick, J.S.; Mash, Jr. E.A.; Avala, R.B.; Aposhian, M.M.
The discovery, importance and significance of monomethylarsonous acid (MMAIII) in urine of humans exposed to inorganic arsenic. In W.R. Chappell, C.O. Abernathy and R.L. Calderon (Eds.), Arsenic Exposure and Health Effects, Elsevier Science. pp. 305-314 (2001). |
| 63. |
Lu, X.; Gong, Z.; Ma, M.; Cullen, W.R.; Aposhian, H.V.; Zheng, B.;
Gurzau, E.S.; Le, X.C.
Speciation of human urinary arsenic including the trivalent methylation metabolites. In W.R. Chappell, C.O. Abernathy and R.L. Calderon (Eds.), Arsenic Exposure and Health Effects, Elsevier Science. pp. 339-352 (2001). |
| 62. |
Le, X.C.
Speciation of arsenic in water and biological matrices. American Water Works Associaiton (AWWA) and AWWA Research Foundation, Denvor, CO. ISBN 1-58321-085-7. pp.1-145 (2001). |
| 61. |
Le, X.C.
Arsenic speciation in the environment and humans. In Frankenberger, Jr, W.T. (Ed), Environmental Chemistry of Arsenic. Marcel Dekker, Inc. New York, Chapter 4, pp.95-116 (2001). |
| 60. |
Tan, W.G.; Carnelley, T.J.; Murphy, P.; Wang, H.; Lee, J.; Barker, S.;
Weinfeld, M.; Le, X.C.
Detection of DNA adducts of benzo[a]pyrene using immuno-electrophoresis with laser-induced fluorescence: analysis of A549 cells. Journal of Chromatography A, 924, 377-386 (2001). |
| 59. |
Weinfeld, M.; Xing, J.Z.; Lee, J.; Leadon, S.A.; Cooper, P.K.; Le, X.C.
Factors influencing the removal of thymine glycol from DNA in gama-irradiated human cells. Progress in Nucleic Acid Research and Molecular Biology, 68, 139-149 (2001). |
| 58. | Xing, J.Z.; Carnelley, T.; Lee, J.; Watson,
W.; Weinfeld, M.; Le, X.C.
Assay for DNA damage using immunochemical recognition and capillary electrophoresis. Methods in Molecular Biology,162/163, 419-428 (2001). |
| 57. |
Yalcin, S.; Le, X.C.
Speciation of arsenic using solid phase extraction cartridges. Journal of Environmental Monitoring, 3, 81-85 (2001). |
2000 | |
| 56. |
Wan, Q.-H.; Le, X.C.
Studies of protein-DNA interactions by capillary electrophoresis laser-induced fluorescence polarization. Analytical Chemistry, 72, 5583-5589 (2000). |
| 55. |
Le, X.C.; Lu, X.; Ma, M.; Cullen, W.R.; Aposhian, V.; Zheng, B.
Speciation of key arsenic metabolic intermediates in human urine. Analytical Chemistry, 72, 5172-5177 (2000). |
| 54. |
Le, X.C.; Yalcin, S.; Ma, M.
Speciation of submicrogram per liter levels of arsenic in water: On-site species separation integrated with sample collection. Environmental Science & Technology, 34, 2342-2347 (2000). |
| 53. | Le, X.C.; Ma, M.; Lu, X.; Cullen, W.R.;
Aposhian, V.; Zheng, B.
Determination of monomethylarsonous acid, a key arsenic methylation intermediate, in human urine. Environmental Health Perspectives, 108, 1015-1018 (2000). |
| 52. | Le, X.C.; Weinfeld, M.; Xing, J.Z.
Methods or quantitating low level modifications of nucleotide sequences. United tates patent No. 6,132,968. October 17, 2000. |
| 51. | Xing, J.Z.; Lee, J.; Leadon, S.A.;
Weinfeld, M.; Le, X.C.
Measuring DNA damage using capillary electrophoresis with laser induced fluorescence detection. Methods, 22, 157-163 (2000). |
| 50. | Aposhian, V.H.; Gurzau, E.S.; Le, X.C.;
Gurzau, A.; Healy, S.M.; Lu, X.; Ma, M.; Yip, L.; Zakharyan, R.A.;
Maiorino, R.M.; Dart, R.C.; Gonzalez-Ramirez, D.; Morgan, D.; Avram, D.;
Aposhian, M.M.
Occurrence of monomethylarsonous acid in urine of humans exposed to inorganic arsenic. Chemical Research in Toxicology, 13, 693-697 (2000). |
| 49. | Aposhian, H.V.; Zheng, B.; Aposhian, M.M.;
Le, X.C.; Cebrian, M.E.; Cullen, W.R.; Zakharyan, R.A.; Ma, M.; Dart,
R.C.; Cheng, Z.; Andrews, P.; Yip, L.; O'Malley, G.F.; Maiorino, .M.; Van
Voorhies, W.; Healy, S.M.; Titcomb, A.
DMPS-Arsenic challenge test: Modulation of arsenic species, including monomethylarsonous acid, excreted in human urine. Toxicology & Applied Pharmacology, 165, 74-83 (2000). |
| 48. | Li, X.-F.; Ren, H.; Le, X.C.; Qi, M.;
Ireland, I.; Dovichi, N.J.
Migration time correction for analysis of derivatized amino acids and oligosaccharides using micellar capillary electrochromatography. Journal of Chromatography A, 869, 375-384 (2000). |
| 47. | Ma, M.; Le, X.C.; Hu, B.; Jiang, Z.C.
High performance liquid chromatography with hydride generation atomic fluorescence detection for rapid urinary arsenic speciation. Journal of Analytical Science, 16, 89-96 (2000). |