| FACULTY OF ENGINEERING | UNIVERSITY OF ALBERTA |
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Journal ArticlesBarona, D., Shamsaddini, A., Aisenstat, M., Thalberg, K., Lechuga-Ballesteros, D., Dmadzadeh, B., Vehring, R.: Modulated Uniaxial Compression Analysis of Respirable Pharmaceutical Powders. KONA Powder and Particle Journal, doi.org/10.14356/kona.2021014, 2021. Liang, L., Carrigy, N.B., Kariuki, S., Muturi, P., Onsare, R., Nagel, T., Vehring, R., Connerton, P.L., Connerton, I.E.: Development of a Lyophilization Process for Campylobacter Bacteriophage Storage and Transport. Microorganisms 8, 282, doi: 10.3390/microorganisms8020282, 2020. Carrigy, N. B., Liang, L., Wang, H., Kariuki, S., Nagel, T. E., Connerton, I. F., Vehring, R. Trileucine and Pullulan Improve Anti-Campylobacter Bacteriophage Stability in Engineered Spray-Dried Microparticles. Annals of Biomedical Engineering. 2019. Accepted author version. Carrigy, N. B., Larsen, S. E., Reese, V., Pecor, T., Harrison, M., Kuehl, P. J., Hatfull, G. F., Sauvageau, D., Baldwin, S. L., Finlay, W. H., Coler, R. N., Vehring, R.: Prophylaxis of Mycobacterium tuberculosis H37Rv Infection in a Preclinical Mouse Model via Inhalation of Nebulized Bacteriophage D29. Antimicrobial Agents and Chemotherapy. Accepted. 2019. Author version. Carrigy, N. B., Liang, L., Wang, H., Kariuki, S., Nagel, T. E., Connerton, I. F., Vehring, R.: Spray-dried anti-Campylobacter bacteriophage CP30A powder suitable for global distribution without cold chain infrastructure. International Journal of Pharmaceutics 569(5): 118601, 2019. Accepted manuscript. Ordoubadi, M., Gregson, F.K.A., Melhem, O., Barona, D., Miles, R.E.H., D'Sa, D., Gracin, S., Lechuga-Ballesteros, D., Reid, J.P., Finlay, W.H., Vehring, R.: Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics. Pharmaceutical Research, 36, 100 (2019), doi: https://10.1007/s11095-019-2630-7. Accepted author version. Carrigy, N., Vehring, R.: Engineering Stable Spray Dried Biologic Powder for Inhalation, in Pharmaceutical Inhalation Aerosol Technology, eds. Hickey, A. J., da Rocha, S., Taylor & Francis, 2019, pp. 291 – 326. Carrigy, N. B., Ordoubadi, M., Liu, Y., Melhem, O., Barona, D., Wang, H., Milburn L., Ruzycki, C. A., Finlay, W. H., Vehring, R.: Amorphous Pullulan Trehalose Microparticle Platform for Respiratory Delivery. International Journal of Pharmaceutics, 563: 156-168, 2019. Accepted manuscript. Ly, A., Carrigy, N.B., Wang, H., Harrison, M., Sauvageau, D., Martin, A.R., Vehring, R., Finlay, W.H.: Atmospheric Spray Freeze Drying of Sugar Solution with Phage D29. Frontiers in Microbiology, 10, 1-11, 2019. Wang,
H., Nobes, D. S., Vehring, R.: Particle
Surface Roughness Improves Colloidal Stability of Pressurized
Pharmaceutical
Suspensions. Pharmaceutical Research, 36,
doi.org/10.1007/s11095-019-2572-0,
2019. Leung, S. S. Y., Carrigy, N. B., Vehring, R., Finlay, W. H., Morales, S., Carter, E. A., Britton, W. J., Kutter, E., Chan, H.-K.: Jet Nebulization of Bacteriophages with Different Tail Morphologies – Structural Effects. International Journal of Pharmaceutics, 554, 322-326, 2019. Wang,
H., Tan, P., Barona, D., Li,
G., Hoe, S., Lechuga-Ballesteros, D., Nobes, D. S., Vehring, R.: Characterization
of the Suspension Stability of Pharmaceuticals using a Shadowgraphic
Imaging
Method. International Journal of Pharmaceutics,
548 (1),
128-138, 2018.
Ivey,
J.W.,Bhambri, P., Church, T.K., Lewis, D.A., Vehring, R.: Experimental
Investigations of Particle Formation from Propellant and Solvent
Droplets Using
a Monodisperse Spray Dryer. Aerosol
Science and Technology, 52
(6), 702-716, 2018. Ruzycki,
C., Martin, A., Vehring,
R., Finlay, W.: An In
Vitro Examination of the Effects of Altitude on Dry
Powder Inhaler Performance. Journal of Aerosol Medicine and
Pulmonary Drug
Delivery
31 (4): 221-236, 2018. Carrigy,
N.B., Chang, R.Y.,
Leung, S.S.Y., Harrison, M., Petrova, Z., Pope, W.H., Hatfull, G.F.,
Britton,
W.J., Chan, H.-K., Sauvageau, D., Finlay, W.H., Vehring, R.: Anti-Tuberculosis Bacteriophage D29 delivery
with a Vibrating
Mesh Nebulizer, Jet Nebulizer, and Soft Mist Inhaler.
Pharmaceutical
Research, 34 (10): 2084-2096, 2017. Author version Wang,
H., Barona, D., Oladepo, S.,
Williams, L., Hoe, S., Lechuga-Ballesteros, D., Vehring, R.: Macro-Raman spectroscopy for bulk
composition and homogeneity
analysis of multi-component pharmaceutical powders. Journal
of
Pharmaceutical and Biomedical Analysis, 141 (2017):
180-191. Ivey,
J.W., Bhambri, P., Church,
T.K., Lewis, D.A., Elbayomy, S., McDermott, M.T., Finlay, W.H.,
Vehring, R.: Humidity affects the morphology of particles
emitted from
beclomethasone dipropionate pressurized metered dose inhalers. International Journal of
Pharmaceutics, 520 (1-2):
207-215, 2017. Author version. Ferraz-Albani,
L., Baldelli, A., Knapp, C. J., Jäger, W., Vehring, R., Nobes, D. S.,
Olfert,
J. S., Kostiuk, L. W.: Enhanced Evaporation of Micro-Scale Droplets
with an Infrared
Laser. Journal of Heat Transfer, 139 (1),
011503-1 – 011503-8, 2017.
Baldelli, A.
Vehring, R.: Control of the Radial Distribution of
Chemical Components in Spray
Dried Crystalline Microparticles. Aerosol Science and
Technology, 50
(10), 1130-1142, 2016. Baldelli,
A., Vehring, R.: Analysis of Cohesion Forces between
Monodisperse Microparticles
with Rough Surfaces. Colloids and Surfaces
A: Physicochemical and
Engineering Aspects, 506, 179-189, 2016. Baldelli,
A., Power, R., Miles, R., Reid, J. P., Vehring, R.: Effect of Crystallization Kinetics on the
Properties of Spray
Dried Microparticles. Aerosol Science and
Technology, 50 (7),
693-704, 2016. Leung, S.
Y., Parumasivam, T., Gao, F. G., Carrigy, N. B., Vehring, R., Finlay,
W. H.,
Morales, S., Britton, W. J., Kutter, E., Chan, H.-K.: Production of Inhalation Phage Powders Using
Spray Freeze
Drying and Spray Drying Techniques for Treatment of Respiratory
Infections,
Pharmaceutical Research, 33 (6), 1486-1496, 2016. Azhdarzadeh,
M., Shemirani, F. M., Ruzycki, C. A., Baldelli, A., Ivey, J., Barona,
D.,
Church, T., Lewis, D., Olfert, J. S., Finlay, W. H., Vehring, R.: An Atomizer to Generate Monodisperse
Droplets from High Vapor
Pressure Liquids. Atomization &
Sprays, 26 (2), 121-134,
2016. Ivey,
J.W., Vehring, R., Finlay,
W.H.: Understanding Pressurized Metered Dose
Inhaler Performance.
Expert Opinion on Drug Delivery, 12
(6): 901-916. 2015. Morin,
C.M.D., Ivey, J.W., Titosky, J.T.,
Suderman, J.D., Olfert, J.S., Vehring, R., Finlay, W.H.: Performance
of Pressurized Metered-Dose Inhalers at Extreme Temperature Conditions.
Journal of Pharmaceutical Sciences, 103 (11),
3553-3559, 2014. Azhdarzadeh,
M., Olfert, J.,
Vehring, R., Finlay, W. H.: Effect of Electrostatic Charge on Deposition
of Uniformly
Charged Monodisperse Particles in the Nasal-extrathoracic Airways of an
Infant.
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 28 (1): 30-34. 2014. Ruzycki,
C. A., Golshahi, L.,
Vehring, R., Finlay, W. H.: Comparison
of In Vitro
Deposition of Pharmaceutical Aerosols in an Idealized Child Throat
with In Vivo Deposition in the Upper Respiratory Tract of Children.
Pharmaceutical Research, 31 (6), 1525-1535, 2014. Hoe,
S., Boraey, M. A., Ivey, J. W.,
Finlay, W. H., Vehring, R.: Manufacturing and Device Options for the
Delivery of
Biotherapeutics. Journal of Aerosol Medicine and Pulmonary Drug Delivery,
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 27
(5),
315-328, 2014. Titosky,
J. T. F., Morin, C. M. D.,
Suderman, J. D., Olfert, J. S., Finlay, W. H., Vehring, R.: The
Effect of Altitude on Inhaler Performance. Journal of
Pharmaceutical
Sciences, 103, 2116-2124, 2014. Wang,
H., Boraey, M. A., Williams,
L., Lechuga-Ballesteros, D., Vehring, R.: Low-frequency
Shift Dispersive Raman Spectroscopy for the Analysis of Respirable
Dosage Forms.
International Journal of Pharmaceutics, 469, 197-205,
2014. Borojeni,
A.A.T, Noga, M. L.,
Vehring, R., Finlay, W. H.: Measurements of Total Aerosol Deposition in
Intrathoracic
Conducting Airway Replicas of Children. Journal of Aerosol
Science, 73,
39 – 47, 2014. Azhdarzadeh,
M., Olfert, J.,
Vehring, R., Finlay, W. H.: Effect of Induced Charge on Deposition of
Uniformly Charged
Particles in a Pediatric Oral-extrathoracic Airway. Aerosol
Science and
Technology, 48, 508 – 514, 2014. Ivey,
J. W., Lewis, D., Church, T.,
Finlay, W. H., Vehring, R.: A Correlation Equation for the Mass Median
Aerodynamic Diameter
of the Aerosol Emitted by Solution Metered Dose Inhalers.
International
Journal of Pharmaceutics, 465, 18-24, 2014. Author version. Hoe,
S., Ivey, J. W., Boraey, M. A.,
Shamsaddini-Shahrbabak, A., Javaheri, E., Matinkhoo, S., Finlay, W. H.,
Vehring, R.: Use of a Fundamental Approach to
Spray-Drying Formulation
Design to Facilitate the Development of Multi-Component Dry Powder
Aerosols for
Respiratory Drug Delivery. Pharmaceutical Research, 31,
449-465,
2014. Azhdarzadeh,
M., Olfert, J.,
Vehring, R., Finlay, W. H.: Effect of Electrostatic Charge on
Oral-Extrathoracic Deposition
for Uniformly Charged Monodisperse Aerosols. Journal
of Aerosol
Science, 68, 38-45, 2014. Boraey,
M.A., Vehring, R.: Diffusion Controlled Formation of
Microparticles.
Journal of Aerosol Science, 67, 131-143, 2014. Hoe,
S., Semler, D. D., Goudie, A.
D., Lynch, K. H., Matinkhoo, S., Finlay, W. H., Dennis, J. J., Vehring,
R.: Respirable Bacteriophages for the Treatment
of Bacterial Lung
Infections. Journal of Aerosol Medicine and Pulmonary Drug
Delivery, 26,
317-335, 2013. Javaheri,
E., Shemirani, F. M.,
Pichelin, M., Katz, I. M, Caillibotte, G., Vehring, R., Finlay, W. H.: Deposition Modeling of Hygroscopic Saline
Aerosols in the Human
Respiratory Tract: Comparison between Air and Helium-Oxygen as Carrier
Gases.
Journal of Aerosol Science, 64, 81-93, 2013. Shemirani,
F. M., Hoe, S., Lewis,
D., Church, T., Vehring, R., Finlay, W. H.:
In-vitro
investigation of the effect of ambient humidity on
regional delivered dose with solution and suspension MDI.
Journal of
Aerosol Medicine and Pulmonary Drug Delivery, 26,
215-222, 2013. Golshahi,
L., Noga, M., Vehring, R.,
Finlay, W. H.: An In
vitro Study on the Deposition of Micrometer-sized
Particles in the Extrathoracic Airways of Adults during Tidal Oral
Breathing.
Annals of Biomedical Engineering, 41, 979-989,
2013. Boraey,
M. A., Hoe, S., Sharif, H.,
Miller, D. P., Lechuga-Ballesteros, D., Vehring, R.: Improvement of the Dispersibility of
Spray-dried Budesonide
Powders using Leucine in an Ethanol-water Cosolvent System.
Powder
Technology, 236, 171-178, 2013. Golshahi,
L., Vehring, R., Noga, M.,
Finlay, W. H.: In
Vitro Deposition of Micrometer-sized Particles in the
Extrathoracic Airways of Children during Tidal Breathing.
Journal of
Aerosol Science, 57, 14-21, 2013. Vehring,
R., Lechuga-Ballasteros,
D., Joshi, V., Noga, B., Dwivedi, S.K.: Cosuspensions
of
Microcrystals and Engineered Microparticles for Uniform and Efficient
Delivery
of Respiratory Therapeutics from Pressurized Metered Dose Inhalers.
Langmuir 28 (42), 15015-15023,
2012. Shemirani,
F.M., Hoe, S., Lewis, D.,
Church, T., Vehring, R., Finlay, W.H. In
Vitro
Investigation of the Effect of Ambient Humidity on Regional Delivered
Dose with
Solution and Suspension MDIs. J Aerosol Med. Pulm. Drug
Deliv. 26,
1-8, 2012. Lechuga-Ballasteros,
D., Noga, B.,
Vehring, R., Cummings, R.H., Dwivedi, S.K.: Novel
Cosuspension
Metered-Dose Inhalers for the Combination Therapy of Chronnic
Obstructive
Pulmonary Disease and Asthma. Future Medicinal Chemistry 3,
1703-1718, 2011. Matinkhoo,
S., Lynch, K.H., Dennis,
J.J., Finlay, W.H., Vehring, R.: Spray
Dried Respirable Powders Containing Bacteriophages for
the Treatment of Pulmonary Infections. J. Pharm Sci., 100,
5197-5205, 2011. Feng,
A.L., Boraey, M.A., Gwin,
M.A., Finlay, P.R., Kuehl, P.J., Vehring, R.:Mechanistic
models facilitate efficient development of leucine containing
microparticles
for pulmonary drug delivery. Int. J. Pharmaceutics: 409,
156-163,
2011. Ivey,
J., Vehring, R.:The
use of modeling in spray drying of emulsions and suspensions
accelerates
formulation and process development. Computers &
Chemical Engineering: 34,
1036, 2010. Vehring, R., Foss, W. R., Lechuga-Ballesteros, D.: Particle Formation in Spray Drying . J. Aerosol Science 38:728, 2007. (#1 Article for J. Aerosol Science, Jul. to Sept. 2007) Vehring,
R.: Red-Excitation
Dispersive Raman Spectroscopy is a Suitable Technique for Solid State
Analysis
of Respirable Pharmaceutical Powders. Appl. Spectrosc., 59:
286,
2005. Chan,
H.-K., Clark, A. R., Feeley,
J. C., Kuo, M.-C., Lehrman, S. R., Pikal-Cleland, K., Miller, D. P.,
Vehring,
R., Lechuga-Ballesteros, D.: Physical Stability of Salmon Calcitonin
Spray-Dried Powders for
Inhalation. J. Pharm Sci., 93: 792, 2004.
Abstract Vehring,
R., Aardahl, C. L.,
Schweiger, G., and Davis, E. J.: The Characterization
of Fine Particles Originating from an Uncharged Aerosol: Size
Dependence and
Detection Limits for Raman Analysis. J. Aerosol Sci., 29:
1045,
1998. Abstract Vehring,
R., Aardahl, C.L., Davis,
E.J., Schweiger, G., Covert D.S.: Electrodynamic
Trapping and Manipulation of Particle Clouds.
Rev.Sci.Instrum., 68: 1, 1997. Abstract Aardahl,
C. L., Vehring, R., Davis,
E. J., Schweiger, G., Swanson, B. D.: Trapping
Two-Particle Arrays in a Double-Ring Electrodynamic Balance.
J. Aerosol
Sci., 28: 1491, 1997. Abstract Moritz,
H., Vehring, R., Schweiger,
G.: Investigation
of the Desorption of Acetylene from Acetone Microdroplets by Raman
Spectroscopy.
J. Aerosol Sci., 27:S517,1996. Vehring,
R., Moritz, H., Niekamp,
D., Heinrich, P., and Schweiger, G.: Linear Raman
Spectroscopy on Droplet Chains: A New Experimental Method for the
Analysis of
Fast Transport Processes and Reactions on Microparticles.
Appl. Spectrosc.,
49: 1215, 1995. Paper. Vehring,
R., Schweiger, G.: Optical Determination of the Temperature of
Transparent
Microparticles. Appl. Spectrosc., 46: 25,
1992. Abstract Conferences |
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