FACULTY OF ENGINEERING UNIVERSITY OF ALBERTA  
Department of Mechanical Engineering
Particle Engineering - Home Contact



    Upcoming Contributions



Because of conference cancellations due to the COVID-19 outbreak, the are no upcoming contributions at this time.

     Recent Publications and Conference Contributions



Nagel, T., Kariuki, S., Muturi, P., Nyambura, A., Nganga, G., Kariuki Ngumo, J., Connerton, I., Liang, L., Connerton, P., Vehring, R., Carrigy, N.: Development of a Campylobacter Phage Product to     Decontaminate Poultry Meat in Kenya. Phage Futures Congress, Washington, DC, February 5-6,         2020.

Carrigy, N. B., Liang, L., Wang, H., Kariuki, S., Nagel, T. E., Connerton, I. F., Vehring, R. Trileucine and Pullulan Improve Anti-Campylobacter Bacteriophage Stability in Engineered Spray-Dried Microparticles. Annals of Biomedical Engineering. 2019. Accepted author version.

Carrigy, N. B., Ordoubadi, M. Liu, Y., Melhem, O., Barona, D., Wang, H., Milburn, L., Ruzycki, C. A., Finlay, W. H., Vehring, R.: Amorphous pullulan trehalose microparticle platform for respiratory delivery. AAAR 37th Annual Conference, Portland, OR, 2019. Abstract. Presentation.

Carrigy, N. B., Larsen, S. E., Reese, V., Pecor, T., Harrison, M., Kuehl, P. J., Hatfull, G. F., Sauvageau, D., Baldwin, S. L., Finlay, W. H., Coler, R. N., Vehring, R.: Prophylaxis of Mycobacterium tuberculosis H37Rv Infection in a Preclinical Mouse Model via Inhalation of Nebulized Bacteriophage D29. Antimicrobial Agents and Chemotherapy. Accepted. 2019. Author version.

Carrigy, N. B., Liang, L., Wang, H., Kariuki, S., Nagel, T. E., Connerton, I. F., Vehring, R.: Spray-dried anti-Campylobacter bacteriophage CP30A powder suitable for global distribution without cold chain infrastructure. International Journal of Pharmaceutics 569(5): 118601, 2019. Accepted manuscript.

Carrigy, N. B., Larsen, S. E., Reese, V., Pecor, T., Harrison, M., Kuehl, P. J., Hatfull, G., Sauvageau, D., Finlay, W. H., Coler, R. N., Vehring, R.:  Investigating prophylactic respiratory delivery of active bacteriophage D29 to protect against inhaled Mycobacterium tuberculosis H37Rv in Mice. 5th International TB-meeting, Groningen, Netherlands, 2019. (Winner of the 2019 Anne de Boer Award.) Abstract. Presentation.

Gomez, M., Ordoubadi, M., Wang, H., Carrigy, N. B., Barona, D., Jar, C., Vehring, R., Archer, M., Press, C., McCollum, J., Kramer, R., Fox, C. Spray drying adjuvanted tuberculosis vaccine encapsulates nano-emulsions within a dry powder inhalable product. 5th International TB-meeting, Groningen, Netherlands, 2019. Abstract. Presentation

Vehring, R.: Physicalism or Imago Dei? An Exegesis of the Free Will Doctrine of Sirach 15: 11-20.  3rd Annual Conference of the Society of Catholic Scientists, Notre Dame, IN, 2019. Poster.

Carrigy, N. B.,  Larsen, S. E., Harrison, M., Kuehl, P. Hatfull, G., Sauvageau, D., Finlay, W. H., Coler, R. N., Vehring, R.: Exploring inhalation of nebulized bacteriophage D29 to provide prophylactic protection against Mycobacterium tuberculosis aerosol in a preclinical mouse model. 22nd World Congress of the International Society for Aerosols in Medicine, Montreux, Switzerland, 2019. Abstract. Poster.

Ly, A., Carrigy, N. B., Wang, H., Harrison, M., Sauvageau, D., Martin, A. R., Vehring, R., Finlay, W. H.: Atmospheric Spray Freeze Drying of Bacteriophage D29 with Sugars. 22nd World Congress of the International Society for Aerosols in Medicine, Montreux, Switzerland, 2019. Poster.

Carrigy, N. B., Ly, A., Harrison, M., Sauvageau, D., Martin, A., Finlay, W. H., Vehring, R.: Comparison of spray drying and atmospheric spray freeze drying for the production of active anti-tuberculosis bacteriophage D29 dry powder for inhalation. Respiratory Drug Delivery Europe 2019, Lisbon, Portugal.  Abstract. Poster.

Wang, H., Nobes, D. S., Finlay, W. H., Vehring, R.: Agitation method affects colloidal stability of pharmaceutical suspensions. Respiratory Drug Delivery Europe 2019, Lisbon, Portugal. (Winner of the 2019 Peter R. Byron Award.) Abstract. Poster.

Wang, H., Nobes, D. S., Finlay, W. H., Vehring, R.: Increasing particle surface roughness as a promising strategy to improve colloidal stability of pharmaceutical suspensions. Respiratory Drug Delivery Europe 2019, Lisbon, Portugal. Vol 2. Abstract. Poster.

Carrigy, N., Vehring, R.: Engineering Stable Spray Dried Biologic Powder for Inhalation, in Pharmaceutical Inhalation Aerosol Technology, eds. Hickey, A. J., da Rocha, S., Taylor & Francis, 2019, pp. 291 – 326.

Carrigy, N. B., Ordoubadi, M., Liu, Y., Melhem, O., Barona, D., Wang, H., Milburn L., Ruzycki, C. A., Finlay, W. H., Vehring, R.: Amorphous Pullulan Trehalose Microparticle Platform for Respiratory Delivery. International Journal of Pharmaceutics, 563: 156-168, 2019. Accepted manuscript.

Ly, A., Carrigy, N.B., Wang, H., Harrison, M., Sauvageau, D., Martin, A.R., Vehring, R., Finlay, W.H.: Atmospheric Spray Freeze Drying of Sugar Solution with Phage D29. Frontiers in Microbiology, 10, 1-11, 2019.

Wang, H., Nobes, D. S., Vehring, R.: Particle Surface Roughness Improves Colloidal Stability of Pressurized Pharmaceutical Suspensions. Pharmaceutical Research, 36 (43): doi.org/10.1007/s11095-019-2572-0, 2019. Author version

Leung, S. S. Y., Carrigy, N. B., Vehring, R., Finlay, W. H., Morales, S., Carter, E. A., Britton, W. J., Kutter, E., Chan, H.-K.: Jet Nebulization of Bacteriophages with Different Tail Morphologies – Structural EffectsInternational Journal of Pharmaceutics, 554, 322-326, 2019. 

Vehring, R.: Mechanistic Understanding of Microparticle Formation in Respiratory Applications. Drug Delivery to the Lungs, Edinburgh (DDL Lecture presented Dec. 12, 2018). 

Wang, H., Tan, P., Barona, D., Li, G., Hoe, S., Lechuga-Ballesteros, D., Nobes, D. S., Vehring, R.: Characterization of the Suspension Stability of Pharmaceuticals using a Shadowgraphic Imaging Method. International Journal of Pharmaceutics, 548 (1), 128-138, 2018.     

Ivey, J.W., Bhambri, P., Church, T. K., Lewis, D. A., Vehring, R.: Experimental Investigations of Particle Formation from Propellant and Solvent Droplets Using a Monodisperse Spray DryerAerosol Science and Technology, 52 (6), 702-716, 2018. 

Leung, S.S.Y., Parumasivam, T., Nguyen, Gengenbach, T., Carter, E.A., Carrigy, N. B., Wang, H., Vehring, R., Finlay, W. H., Morales, S., Britton, J., Kutter, E., Chan, H.-K.: Effect of Storage Temperature on the Stability of Spray Dried Bacteriophage Powders. European Journal of Pharmaceutics and Biopharmaceutics, 127, 213-222, 2018. 

Gomez, M., Ordoubadi, M., McAllister, R. A., Melhem, O., Barona, D., Gracin, S., Ajmera, A., Lechuga-Ballesteros, D., Finlay, W. H., Vehring, R.: Monodisperse Droplet Chain Technique to Support Development of Co-solvent Based Inhalation Products. Respiratory Drug Delivery 2018, Tuscon, AZ. Vol. 2: 563-568. AbstractPoster

Ivey, J. W., Vehring, R.: An In-Silico Investigation of Formulation and Droplet Size Effects on the Aerodynamic Particle Size Distributions of Suspension Pressurized Metered Dose Inhalers. Respiratory Drug Delivery 2018, Tucson, AZ. Vol. 2: 551-556. AbstractPoster

Ivey, J. W., Barona, D., Gomez, M., Kuan, L., McAllister, R., Oberhagemann, L., D’Sa, D., Lechuga-Ballesteros, D., Ajmera, A., Gracin, S., Vehring, R.: Isokinetic In-line Sampling Enables Rapid Characterization of Atomizers and Cyclones for Spray Drying process development. Respiratory Drug Delivery 2018, Tucson, AZ. Vol. 2: 557-562. (Winner of the 2018 Peter R. Byron AwardAbstractPoster

Ordoubadi, M., Gregson, F., Finlay, W. H., Vehring, R., Reid, J. P.: Interaction of Evaporating Multicomponent Microdroplets with Humid Environments. Respiratory Drug Delivery 2018, Tuscon, AZ. Vol. 2: 569-572. AbstractPoster

Wang, H., Tan, P., Barona, D., Li, G., Hoe, S., Lechuga-Ballesteros, D., Nobes, D., Vehring, R.: A New Shadowgraphic Imaging Method for the Suspension Stability Analysis of Pressurized Metered Dose Inhalers. Respiratory Drug Delivery 2018 Tucson, AZ. Vol. 2: 573-578. AbstractPoster.

Ruzycki, C., Martin, A., Vehring, R., Finlay, W.: An In Vitro Examination of the Effects of Altitude on Dry Powder Inhaler Performance. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 31 (4): 221-236. 2018. 

Haddrell, A. E., Lewis, D., Church, T., Vehring, R., Murnane, D., Reid, J. P.: Pulmonary Aerosol Delivery and the Importance of Growth Dynamics. Therapeutic Delivery, 8 (12), 1051-1061, 2017. 

Wang, H., Bhambri, P., Ivey, J., Vehring, R.: Design and Pharmaceutical Applications of a Low Flow Rate Single-Nozzle Impactor. International Journal of Pharmaceutics, 533, 14-25, 2017. 

Carrigy, N. B., Chang, R. Y., Leung, S. S.Y., Harrison, M., Petrova, Z., Pope, W. H., Hatfull, G. F., Britton, W. J., Chan, H.-K., Sauvageau, D., Finlay, W. H., Vehring R.: Anti-Tuberculosis Bacteriophage D29 delivery with a Vibrating Mesh Nebulizer, Jet Nebulizer, and Soft Mist Inhaler.  Pharmaceutical Research 34 (10), 2084-2096, 2017. Accepted author version 

Wang, H., Barona, D., Oladepo, S., Williams, L., Hoe, S., Lechuga-Ballesteros, D., Vehring, R.: Macro-Raman spectroscopy for bulk composition and homogeneity analysis of multi-component pharmaceutical powders. Journal of Pharmaceutical and Biomedical Analysis, 141, 180-191, 2017. 

Carrigy, N. B., Chang, R., Leung, S. S. Y., Harrison, M., Pope, W. H., Hatfull, G. F., Britton, W. J., Chan, H.-K., Sauvageau, D., Finlay, W. H., Vehring, R.,: Comparison of Three Aqueous Inhalation Devices for Delivering Anti-tuberculosis Bacteriophage D29. Respiratory Drug Delivery Europe 2017, Nice (Antibes), France. Vol. 2: 345-348.  Abstract. Poster. Presentation.

Leung, S. S. Y., Parumasivam, T., Gao, F. G., Carrigy, N. B., Vehring, R., Finlay, W. H., Morales, S., Britton, W. J., Kutter, E., Chan, H.-K.: Effects of Storage Conditions on the Stability of Spray Dried, Inhalable Bacteriophage PowdersInternational Journal of Pharmaceutics, 521 (1-2), 141-149, 2017. 

Ivey, J. W., Bhambri, P., Church, T. K., Lewis, D. A., McDermott, M. T., Elbayomy, S., Finlay, W. H., Vehring, R.:  Humidity affects the morphology of particles emitted from beclomethasone dipropionate pressurized metered dose inhalers. International Journal of Pharmaceutics, 520 (1-2), 207-215, 2017. Author version 

Ferraz-Albani, L., Baldelli, A., Knapp, C. J., Jäger, W., Vehring, R., Nobes, D. S., Olfert, J. S., Kostiuk, L. W.: Enhanced Evaporation of Micro-Scale Droplets with an Infrared Laser. Journal of Heat Transfer, 139(1), 011503-1 – 011503-8, 2017.

 

 

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