Unsworth Lab
Cardiovascular Biomaterials


larryatjapan

Larry D. Unsworth, Ph.D.

Assistant Professor     Dept. of Chemical and Materials Engineering

Principal Investigator   NRC (Canada), National Institute for Nanotechnology

Adjunct Professor      Faculty of Medicine, Biomedical Engineering Department

 

Review Editor: Frontiers in Neuroengineering



nint



Post-Doctoral Fellows



Dr. S. Abraham
Email: sinoj(at)ualberta.ca
 
Project Title:

Project Summary:

Selected Articles and Conference Abstracts:

Selected Awards:



Dr. Y. Yang
Email: 
 
Project Title:

Project Summary:

Selected Articles and Conference Abstracts:

Selected Awards:



Dr. I. Bushnak
Email: @ualberta.ca
 
Project Title:

Project Summary:

Selected Articles and Conference Abstracts:

Selected Awards:


Ph.D. Candidates



Markian Bahniuk
M BahniukEmail: mbahniuk(at)ualberta.ca
 
Project Title:

Project Summary:

Selected Articles and Conference Abstracts:

Selected Awards:







Mojtaba Binazadeh

MB 2010    Email: binazade(at)ualberta.ca

   Project Title:Intermolecular and surface interactions between polymer     brushes/coatings and protein for anti- biofouling, and development of         novel wet adhesives for engineering and biomedical applications.

   Project Summary: Protein adsorption occurs to some extent on all         implemented biomaterials and it can lead to unwanted host response.         Consequently, design of biomaterials with minimized nonspecific protein         adsorption is of crucial importance. Surface Force Apparatus (SFA) has         been used to experimentally measure the interaction between polymers     and proteins. Here we aim to take advantage of the accuracy of SFA to         understand the effect of surface modification of a biomaterial and                 minimize  the affinity of proteins toward the adsorption on such surfaces.

Selected Articles and Conference Abstracts:

1- “Fast biodegradation of long chain n-alkanes and crude oil at high concentrations with Rhodococcus sp. Moj-3449” Enzyme and Microbial Technology 2009- Vol. 45, P 195-202
2- “Characterization of two-phase flow and its impact on the performance of a Polymer Electrolyte Membrane fuel cell stack” International Journal of Alternative Propulsion 2008 - Vol. 2, No.1  P 26 - 38
3-“Optimization of Biodegradation of Long Chain n-Alkane by Rhodococcus sp. Moj-3449 Using Response Surface Methodology” ChemBiotech’08, Singapore 2008
4-” Characterization of Two-Phase Flow and its Impact on the Performance of a PEM Fuel Cell Stack” Cairo International Conference on Energy & Environment, 2006”
5- “Cooling Load Reduction of Buildings Using Water Pond on its Roof and Side Insulation” 5th Conference on Optimization of Fuel consumption in building, Tehran, Iran, 2006. 


Selected Awards:



Maryam Kabiri
MKEmail: kabiri (at) ualberta.ca
 
Project Title:  
Localized Drug Delivery: Using Tissue Resident Enzymes to Control the Release of Therapeutic Agents from Multi-Functional Hydrogels

Project Summary:
Peptide therapeutics are potently active and highly specific, however, delivering them locally is difficult due to their sensitive structure. This research is directed towards the development of peptide self-assembly, a platform that may allow the delivery of these therapeutics, and to investigate how their physicochemical properties affect innate immunity.

Selected Articles and Conference Abstracts:

1. M. Kabiri, M. Tahriri, M. Rafie nia, Sh. Hojjati Emami, "Preparation & characterization of absorbable hemostat EDC-crosslinked gelatin sponge for surgical applications", (submitted to Bull. Mater. Sci.).
2. M. Kabiri, Y. Dabiri, S. Najarian, "Application of  drug delivery systems in pain management and spasticity", (oral presentation) 11th Iranian congress of Physical Medicine Rehabilitation & Electrodiagnosis, Shiraz, Iran, Oct. 2008.
3. M. Kabiri, R. Imani, Sh. Bonakdar, M. Rafienia , "Synthesis & characterization of absorbable hemostat EDC-crosslinked gelatin sponge for use in surgery",  (oral presentation) 13th  Iranian Conference  of Biomedical engineering, Tehran, Iran, Feb. 2008.
4. R. Imani, M. Kabiri, M. Rafienia,"Synthesis & characterization of biodegradable hemostat gelatin sponge crosslinked with glutaraldehyde" , (oral presentation) 1th  International Biomaterial Conference, Tehran, Iran, Dec. 2006.

Selected Awards:

Provost Doctoral Award, University of Alberta

Aditi Saini
ASEmail: @ualberta.ca
 
Project Title:

Project Summary:

Selected Articles and Conference Abstracts:

Selected Awards
:



M.Sc. Candidates




USRAs

Megan Ross       - April to Dec 2010
Alan So             - April to Aug 2010
Jonathan Yang  - Sept to Dec  2010


Wisest Students

N/A

Graduates/Previous Students

Harsh Deep Singh, M.Sc.
HDSEmail:                        harshdee(at) ualberta.ca
Thesis Topic:           Enzymatic Degradation of Bovine Serum Albumin (BSA)  
                                     Nanoparticles (NPs) for the Purpose of Drug Delivery
Graduation Date:  Dec 2009

Selected Articles and Conference Abstracts:
H-D. Singh, H. Uludag, L.D. Unsworth,"Enzymatic 
Digestion of Coated BSA NPs Designed for Drug Delivery",
Alberta BME Conference-2009, Banff Centre.  (shortlisted for best presentation, top 8 of 50)

H-D. Singh, G. Wang, H. Uludag, L.D. Unsworth,"BSA nanoparticles for controlled drug release: Using MMP2 
cleavable peptides for particle stabilization", Canadian Biomaterials Society Conference-09, Laval University.

H-D. Singh, H. Uludag, L.D. Unsworth,"Bioresponsive Nanoparticles for Cancer Therapy: MMP2 controlled drug release from BSA Nanoparticles", Canadian Materials Science Conference-2008, University of Alberta

Current Placement: Research Associate for Unsworth Labs