Table 2-3. Antibody terminology based on serological behavior

complete antibody

an antibody that can agglutinate red cells in saline solution (usually IgM)
incomplete antibody

an antibody that in saline can only sensitize red cells, not cause cells to agglutinate (usually IgG)
cold agglutinin

an antibody that reacts best in the cold (4°C) and usually does not react at 37°C unless it has a high thermal range
warm agglutinin

an antibody that reacts best at 37°C
naturally occurring antibody
(non-red cell stimulated)

an antibody produced in response to an unknown foreign stimulus, presumably due to ingestion of substances present in nature (plants, animals, bacteria> that chemically resemble blood group antigens (usually IgM)
Immune antibody
(red cell stimulated)

an antibody produced in response to a response to a known foreign antigenic stimulus such as red cell antigens introduced into the curculation by transfusion or pregnancy (usually IgG)
regular antibody

an antibody present in the serum of all persons lacking the corresponding antigen; for the most part, only anti-A and anti-B in the ABO system fit this classification (synonyms = typical antibody, expected antibody)
irregular antibody

an antibody not usually present in the serum of persons lacking the corresponding antigen; most blood group antibodies found in humans are irregular antibodies (synonyms = atypical antibody, unexpected antibody)

Table 2-3