Enrichment Activity #3

ABO Exercise "B" 

E-mail answers to Pat. Questions #1-8 are based on the pedigree shown in Figure 4-5.

1. H genotype of #2

2. ABO genotype of #3

3. H genotype of #1

4. ABO genotype of #1

5. ABO genotype of #4

6. ABO phenotype of #6

7. ABO genotype of #6

8. H genotype of #5

9. Based on the genes inherited, which ABH substances (soluble antigens), if any, would be present in the saliva of the following?

   (a) AB HH sese

   (b) BB hh SeSe

   (c) AB HH Sese

   (d) AO Hh Sese

10. For this secretor test on a group AB patient, is the person (a) a secretor? (b) a non-secretor? or (c) results cannot be interpreted?

    saliva + anti-A + A cells --> negative test

    saliva + anti-B + B cells --> negative test

    saliva + anti-H + O cells --> positive test

11. Group H antigen specificity resides with which terminal sugar?

12. Persons of which blood group(s) produce D-fucosly transferase?

    Questions 13-15 are based on typing results in Table 4-5.

    Table 4-5. ABO typing results

    Patient #		anti-A	anti-B		A1 cells	B cells
    1		4+	--		1+	4+
    2		1+	--		--	4+
    3		4+	4+		--	--
    4		--	4+		4+	--

13. Which patient, if any, is likely

    (a) group A?

    (b) group A₂ with anti-A₁?

    (c) group AB?

    (d) group O?

    (e) group A₃?

    (f) group B?

14. Dolichos biflorus would be helpful in grouping which, if any, patient?

15. Which patient, if any, may show mixed-field agglutination?

EA #3: ABO Exercise "B"