Nikolai Malykhin MD, PhD

Nikolai Malykhin

MD Diploma, Minsk State Medical Institute, Belarus (1998)
Residency in Psychiatry, Republican Clinical Psychiatric Hospital, Minsk, Belarus (1999)
Ph.D. in Psychiatry, Belarusian Medical Academy of Post-Graduate Education, Minsk, Belarus (2003)
Postdoctoral Fellowship, Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada (2008)
780-248-1120
nikolai@ualberta.ca
Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, Research Transition Facility, Room 1069, Edmonton, Alberta, Canada, T6G 2V2

Publications

  1. Choi C, Ogilvie C, Malykhin NV, Ngo J, Hartfeil M, Coupland N (2005). Detection of the Myo-Inositol 4.06 ppm Resonance by Selective J Rewinding: Application to Human Prefrontal Cortex In Vivo.Magnetic Resonance in Medicine 54(6):1536-40.
  2. Choi C, Coupland NJ, Bhardwaj P, Malykhin NV, Gheorghiu D, Allen PS (2006). Measurement of Brain Glutamate and Glutamine by Spectrally-Selective Refocusing at 3 Tesla. Magnetic Resonance in Medicine 55(5):997-1005.
  3. Choi C, Coupland NJ, Kalra S, Bhardwaj P, Malykhin NV, Allen PS (2006). Proton Spectral Editing for Discrimination of Lactate and Threonine 1.31 ppm Resonances in Human Brain In Vivo. Magnetic Resonance in Medicine 56(3):660-5.
  4. Malykhin NV, Bouchard TP, Ogilvie CJ, Coupland NJ, Seres P, Camicioli R (2007). Three-dimensional volumetric analysis and reconstruction of amygdala and hippocampal head, body and tail. Psychiatry Research: Neuroimaging 155(2):155-165.
  5. Bouchard TP, Malykhin NV, Martin WR, Hanstock CC, Emery DJ, Fisher NJ, Camicioli RM (2008). Age and dementia-associated atrophy predominates in the hippocampal head in Parkinson’s disease. Neurobiology of Aging 29(7):1027-39.
  6. Malykhin NV, Concha L, Seres P, Beaulieu C, Coupland NJ (2008). DTI-tractography and reliability analysis for limbic and paralimbic white matter tracts. Psychiatry Research: Neuroimaging 164:132–142.
  7. Malykhin NV, Bouchard TP, Camicioli R, Coupland NJ (2008). Aging hippocampus and amygdala NeuroReport 19(5):543-547.
  8. Malykhin NV, Lebel RM, Coupland N, Wilman A, Carter R (2010). In-vivo quantification of hippocampal subfields using 4.7T Fast Spin Echo imaging. NeuroImage 49(2):1224-30.
  9. Michielse S, Coupland NJ, Camicioli R, Carter R, Seres P, Sabino J, Malykhin NV (2010). Selective effects of aging on brain white matter microstructure: a diffusion tensor imaging tractography study. NeuroImage 52: 1190-201.
  10. Malykhin NV, Carter R, Seres P, Coupland N (2010). Structural changes in the hippocampus in major depressive disorder: contributions of disease and treatment. Journal of Psychiatry and Neuroscience 35(5):337-43.
  11. Malykhin NV, Vahidy S, Michielse S, Coupland N, Camicioli R, Seres P, Carter R (2011). Structural organization of the prefrontal white matter pathways in the adult and aging brain measured by diffusion tensor imaging. Brain Structure and Function, 216 (4): 417-31.
  12. Malykhin NV, Carter R, Hegadoren K, Seres P, Coupland N (2011). Fronto-limbic volumetric changes in major depressive disorder. Journal of Affective Disorders, 136 (3):1104-13.
  13. Lindberg O, Walterfang M, Looi JCL, Malykhin NV, Östberg P, Zandbelt B, Styner M, Velakoulis D, Örndahl E, Cavallin L, Wahlund LO (2012). Shape analysis of the hippocampus in Alzheimer’s disease and subtypes of frontotemporal lobar degeneration. J Alzheimers Dis 30(2):355-65.
  14. Surdhar I, Gee M, Bouchard T, Coupland N, Malykhin NV, Camicioli R (2012). Intact limbic-prefrontal connections and reduced amygdala volumes in Parkinson's disease with mild depressive symptoms. Parkinsonism Relat Disord 8(7):809-13.
  15. Huang Y, Coupland NJ, Lebel RM, Carter R, Seres P, Wilman AH, Malykhin NV (2013). Structural Changes in Hippocampal Subfields in Major Depressive Disorder: A High-Field Magnetic Resonance Imaging Study. Biological Psychiatry. Feb 15. doi: S0006-3223(13)00045-0. 10.1016.
  16. Travis SG, Huang Y, Fujiwara E, Radomski A, Carter R, Seres P, Malykhin NV. (2014) High field structural MRI reveals specific episodic memory correlates in the subfields of the hippocampus. Neuropsychologia 53:233-245.
  17. Travis SG, Coupland N, Silverstone, Huang Y, Fujiwara E, Carter R, Malykhin NV. Dentate gyrus volume and memory performance in major depressive disorder. (2014) J Affect Disord.172C:159-164.
  18. Boccardi M, Bocchetta M, Apostolova LG, Barnes J, Bartzokis G, Corbetta G, DeCarli C, deToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duvernoy H, Duchesne S, Jack CR Jr, Frisoni GB; for the EADC-ADNI Working Group on the Harmonized Protocol for Manual Hippocampal Segmentation. (2014) Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance. Alzheimers Dement. 2014 Aug 14 doi: 10.1016/j.jalz.2014.02.009. [Epub ahead of print].
  19. Frisoni GB, Jack CR, Bocchetta M, Bauer C, Frederiksen KS, Liu Y, Preboske G, Swihart T, Blair M, Cavedo E, Grothe MJ, Lanfredi M, Martinez O, Nishikawa M, Portegies M, Stoub T, Ward C, Apostolova LG, Ganzola R, Wolf D, Barkhof F, Bartzokis G, DeCarli C, Csernansky JG, deToledo-Morrell L, Geerlings MI, Kaye J, Killiany RJ, Lehéricy S, Matsuda H, O'Brien J, Silbert LC, Scheltens P, Soininen H, Teipel S, Waldemar G, Fellgiebel A, Barnes J, Firbank M, Gerritsen L, Henneman W, Malykhin N, Pruessner JC, Wang L, Watson C, Wolf H, deLeon M, Pantel J, Ferrari C, Bosco P, Pasqualetti P, Duchesne S, Duvernoy H, Boccardi M; EADC -European Alzheimer's Disease Consortium and the ADNI - Alzheimer's Disease Neuroimaging Initiative. (2014) The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity. Alzheimers Dement. 2014 Sep 27. doi: 10.1016/j.jalz.2014.05.1756. [Epub ahead of print].
  20. Yushkevich P, Amaral P, Augustinack J, Bender A, Bernstein J, Boccardi M, Boscheta M, Carr V, Ekstrom A, Huand Y, Geerlings M, Kerchner G, Malykhin N, Mueller S, Raz N, Pruessner J, Stark C, Wagner A, Wisse L, Yassa M, Zeineh M. (2015) A quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal gyrus subregions in-vivo MRI: Is unified protocol fisible? Neuroimage (in press).