| Post Secondary Education and Academic Positions Held | |
| Honours and Awards | |
| Professional Affiliations Held | |
| Teaching | |
| Research Interests | |
| Clinical Trials | |
| Research Interactions |
Degrees: B.Sc. (Alberta), M.Sc. (Alberta), M.D. (Calgary), Ph.D. (McGill), FRCPC
Affiliation: Division of Neurology, Department of Medicine
530 Heritage Medical Research Building
University of Alberta
Edmonton, Alberta T6G 2B7
Tel: Office: (780) 407-7153
Lab: (780) 492-1669
Fax: (780) 407-3410
E-Mail: jack.jhamandas@ualberta.ca
Post Secondary Education and Academic Positions Held
| 1976-1979 | M.D. | Medicine | University of Calgary |
| 1979-1980 | Internship | Internal Medicine | Toronto Western Hospital |
| 1980-1981 | Resident | Internal Medicine | Toronto Western Hospital |
| 1981-1984 | Resident | Neurology | Montreal Neurological Institute |
| 1984 | FRCPC | Neurology | McGill University |
| 1984-1987 | Ph.D. MRC Centennial Fellow | Neurosciences | McGill University |
| 1987- | Member | Div. of Neuroscience | University of Alberta |
| 1987- | Member | AMFMR Rehab Neuroscience group | University of Alberta |
| 1987- | Active Medical Staff | Medicine | University of Alberta Hospitals |
| 1987-1992 | Assistant Professor | Medicine (Neurology) | University of Alberta |
| 1988-1993 | MRC Scholar | Medicine (Neurology) | University of Alberta |
| 1992-1997 | Associate Professor | Medicine (Neurology) | University of Alberta |
| 1997- | Professor | Medicine (Neurology) | University of Alberta |
| 1998-1999 | AHFMR Visiting Scientist | Neuroscience | McGill University, Netherlands Inst. Brain Res. |
| 2001- | Canada Research Chair - Tier 1 | Medicine (Neurology) | University of Alberta |
MRC Centennial Fellowship - 1984-1987
1986 Francis McNaughton Prize (awarded by the Canadian Neurological Society)
MRC Scholarship - 1988-1993
Medal in Medicine - 1989 - Royal college of Physicians and Surgeons of Canada
Elected Member - 1993 - American Neurological Assn. (Membership selected on basis of academic achievements)
Elected Member - 1995 - Alpha Omega Alpha Honor Medical Society
Killam Annual Professorship - 1994-95
Department of Medicine Research Achievement Award - 1998
AHFMR Visiting Scientist Award - 1998 - 1999
Professional Affiliations Held
| Royal College of Physicians and Surgeons of Canada | Fellow |
| College of Physicians and Surgeons of Alberta | Member |
| College of Physicians and Surgeons of Alberta | Member |
| American Academy of Neurology | Member |
| Canadian Neurological Society | Member |
| Canadian Association for Neuroscience | Member |
| Society for Neuroscience | Member |
| Canadian Physiological Society | Member |
| Canadian Medical Association | Member |
| Alberta Medical Association | Member |
| American Neurological Association | Member |
| Canadian Stroke Consortium | Member |
| Canadian Stroke Society | Member |
| Alpha Omega Alpha Honour Medical Society | Member |
Undergraduate Courses
| Physiology 261 | CNS & Autonomic Physiology for OT, Physio, Med Lab Science Students |
| Medicine 434 | Neurology for Dentistry students |
| Rehabilitation Medicine 354 | Clinical Neurology for Rehab. students |
| Pharmacology 412 | Drugs and the Nervous System |
| Pharmacology 371 | Neuroscience: Cells, membranes, molecules |
| Neuroscience 450/451 | Laboratory based project; selected readings |
| Neuroscience 472 | Autonomic Neuroscience |
Graduate and Medical Courses
| Physiology 411 | Medical Physiology (CNS clinical lectures) |
| Neuroscience Block DMED 524 | Clinical Neurology for Phase II Medical students |
| Pharmacology 421 | Clinical Pharmacology for Phase ll Medical students |
| Pharmacology 433 | Therapeutics and Problem Solving (Phase ll Medical Students) |
| Pharmacology 512 | Neurotransmitter function (graduate course) |
Clinical Teaching
Phase ll (medical students) bedside clinical neurology teaching sessions
Phase lll (medical students) bedside clinical neurology teaching sessions
Annual pre-Royal College neurology teaching session for residents in Internal Medicine
Out-patient neurology instruction for neurology residents
Clinical neurology instruction during ward and consultation service rounds
Participation in Grand Medical and Neurology Rounds, oral examinations, OSCE. evaluations
Teaching Innovations
Organize and conduct Basic Neuroscience teaching sessions for Neurology residents (equivalent of a full-year graduate course in Neurobiology). Textbook: Principles of Neural Science, Kandel, Schwartz & Jessel, 4th edition.
Principle Investigator for clinical trials in migraine (Glaxo Canada Inc), Stroke (Genentech Inc.) and (Leo Laboratories) -recruited Neurology residents as co-investigators and participants.
Central nervous system control of cardiovascular function: Neurophysiological analysis and anatomical characterization of central autonomic pathways. Neurotransmitter ‑ neuropeptide interactions.
Parkinson's disease: Quantification of motor function including tremor and rigidity in Parkinson's Disease.
Neurodegeneration: Mechanisms of excitotoxicity and neurotransmitter function in the basal forebrain. Amyloid β-protein and Alzheimer=s disease.
Grant Reviewer for Medical Research Council of Canada, Heart and Stroke Foundation of Canada, Canadian Diabetic Association, Alberta Heart and Stroke Foundation, Wellcome Trust (United Kingdom), National Science Association (USA), BC Healthcare Research Foundation.
Glaxo Canada Inc. - A double-blind, placebo-controlled parallel group study of a second 100mg oral dose of GR43275C (sumatriptan) in the treatment of acute migraine attack and of a further 100mg dose in treating headache recurrence. (Sponsor: Glaxo Inc.). Principal Investigator. 1990-91.
Quantification of rigidity in Parkinson's disease. (Supported through MRC grant to Dr. A. Prochazka). Co-investigator. 1993-1996.
Thromolytic therapy in acute stroke - Activase Alteplase (tissue plasminogen activator) A0276g Study. (Sponsor: Genentech Inc.). Principal investigator. 1996-1998
Double-blinded placebo controlled study of two dosages of Nadroparin Calcium (Fraxiparine) in the treatment of acute ischemic stroke. (Sponsor: Sanofi-Winthrop). Co-investigator. 1996-1997.
A multicentre, randomized, double-blind, placebo-controlled study to examine the safety and pharmacokinetics of a single loading dose + multiple maintenance dose infusion regimen of GV150526 in the treatment of patients with a clinical diagnosis of acute stroke. (Sponsor: Glaxo Wellcome). Co-Investigator. 1997.
Tinzaparin in ischemic stroke: Efficacy and safety of Tinzaparin 175 anti-XA IU/KG/Day or 100 Anti-XA IU/KG/Day versus acetylasalicylic acid 300mg/day in treatment of acute ischemic stroke. (Sponsor: Leo Laboratories). Principal Investigator. 1997-1999.
A multicentre, randomized, double-blind trial to compare the efficacy and safety of ZOMIG 2.5mg, Naramig 2.5mg and placebo in the acute treatment of migraine. (Sponsor: Zeneca Pharma Inc). Principal Investigator. 1998-1999.
Dr. Teresa Krukoff (Dept of Cell Biology) on central autonomic regulation.
Dr. Arthur Prochazka (Dept of Physiology) on "Quantification of rigidity in Parkinson's Disease." (Funded in part through MRC Program Project grant.)
Dr. W. Colmers (Dept of Pharmacology) on development of patch clamp recordings in human epileptic brain tissue using infrared video microscopy.
Drs. R.B. Stein (Dept of Physiology), J. Yang (Dept of Physical Therapy) and T. Gordon (Dept of Pharmacology) on motor unit recordings and quantification in spinal cord injured patients.
Dr. C.W. Bourque (Centre for Neuroscience Research, McGill University) on development of an in vitro brain explant preparation to study the effects of amyloid beta-protein on basal forebrain neurons. (Sabbatical leave, 1998-1999).
Dr. R.M. Buijs ( Netherlands Institute for Brain Research) and Dr. V. Goncharuk (Institute for Atherosclerosis, Moscow) on identification and distribution of Neuropeptide FF in the human brain. (Sabbatical leave, 1998-1999).
Dr. A.. Prochazka . Project on Efficacy of Topiramate on treatment of essential tremor.
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